Evidence map›Paper›PMID 39112643›Full record

ArticleScientific reports2024

Photoacoustic imaging of a cyanine dye targeting bacterial infection.

Rowan Swann, Daniel Hernández-Valdés, Luis Rafael Silva, Yusra Mahmood Marfatia, Mohamed E El-Zaria, Afaf R Genady, Jacek M Kwiecien, John F Valliant, Saman Sadeghi

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Rowan SwannDepartment of Chemistry and Chemical Biology, McMaster University, Hamilton, ON, L8S 4L8, Canada.
Daniel Hernández-ValdésDepartment of Chemistry and Chemical Biology, McMaster University, Hamilton, ON, L8S 4L8, Canada.
Luis Rafael SilvaDepartment of Chemistry and Chemical Biology, McMaster University, Hamilton, ON, L8S 4L8, Canada.
Yusra Mahmood MarfatiaDepartment of Chemistry and Chemical Biology, McMaster University, Hamilton, ON, L8S 4L8, Canada.
Mohamed E El-ZariaDepartment of Chemistry and Chemical Biology, McMaster University, Hamilton, ON, L8S 4L8, Canada.
Afaf R GenadyDepartment of Chemistry and Chemical Biology, McMaster University, Hamilton, ON, L8S 4L8, Canada.
Jacek M KwiecienDepartment of Pathology and Molecular Medicine, McMaster University, Hamilton, ON, L8S 4L8, Canada.
John F ValliantDepartment of Chemistry and Chemical Biology, McMaster University, Hamilton, ON, L8S 4L8, Canada.
Saman SadeghiDepartment of Chemistry and Chemical Biology, McMaster University, Hamilton, ON, L8S 4L8, Canada. sadegs10@mcmaster.ca.

Funding

Canadian Foundation of Innovation JELF-35354Natural Sciences and Engineering Research Council of Canada RGPIN-2022-05201Ontario Institute for Cancer Research AO-FR-PET-3D-MAC-RA
6 · The paper itself

Abstract

The development of a non-invasive infection-specific diagnostic probe holds the potential to vastly improve early-stage detection of infection, enabling precise therapeutic intervention and potentially reducing the incidence of antibiotic resistance. Towards this goal, a commercially available bacteria-targeting Zinc(II)-dipicolylamine (ZnDPA)-derived fluorophore, PSVue794, was assessed as a photoacoustic (PA) imaging probe (PIP). A radiolabeled version of the dye, [

Indexed as

Bacterial InfectionsCarbocyaninesFluorescent DyesPhotoacoustic TechniquesAnimalsDisease Models, AnimalFemaleMicePicolinic AcidsTissue DistributionCarbocyaninesFluorescent DyesPicolinic Acids

Identifiers

PMID39112643
PMCPMC11306741

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.