ArticleNature communications2024
Risk of stroke in male and female patients with atrial fibrillation in a nationwide cohort.
Article in Nature communications, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed.
- Female sex-related stroke risk in patients with atrial flutter-comparison between CHA2DS2-VA and CHA2DS2-VASc scores.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2026Article
- Interpretable machine learning models for stroke risk prediction in patients with newly diagnosed atrial fibrillation.NPJ digital medicine · 2026Article
- Breakthrough Stroke in Women With Atrial Fibrillation: A Call for Sex-Specific Care and Better Outcomes.Journal of the American Heart Association · 2026Article
- Sex Differences in Outcomes After Breakthrough Ischemic Stroke on Oral Anticoagulants for Atrial Fibrillation: An ASPERA-R Inverse Probability Weighted Analysis.Journal of the American Heart Association · 2026Article
- Female Sex-Related Stroke Risk in Atrial Fibrillation: A Thing From the Past?Circulation. Arrhythmia and electrophysiology · 2026Article
- Changing patterns of the burden for atrial fibrillation/atrial flutter attributable to high systolic blood pressure in China from 1990 to 2021.Hypertension research : official journal of the Japanese Society of Hypertension · 2026Article
- Heart Failure and Atrial Fibrillation in Women: Pathophysiological Links, Clinical Challenges, and Therapeutic Perspectives.Medicina (Kaunas, Lithuania) · 2026Review
- Sex differences in the association of social determinants of health and adverse cardiovascular outcomes in patients with atrial fibrillation.Open heart · 2025Article
- Asia Pacific Heart Rhythm Society (APHRS) scientific statement on stroke prevention strategies in patients with device-detected atrial fibrillation: the 4S-DDAF approach.The Lancet regional health. Western Pacific · 2025Review
- Relation of the non-high-density lipoprotein cholesterol to high-density lipoprotein cholesterol ratio to residual risk in anticoagulated patients with atrial fibrillation: a report from the prospective Murcia AF Project III cohort.Cardiovascular diabetology · 2025Observational
- Stroke risk stratifications according to CHA2DS2-VASc vs. CHA2DS2-VA in patients with atrial fibrillation: insights from the GLORIA-AF registry.European heart journal. Cardiovascular pharmacotherapy · 2025Article
- Temporal trends in ischemic stroke and female sex as a risk modifier in atrial fibrillation: insights from non-anticoagulated Asian patients in a nationwide cohort study.The Lancet regional health. Western Pacific · 2025Article
- Evidence Gaps and Lessons in the Early Detection of Atrial Fibrillation: A Prospective Study in a Primary Care Setting (PREFATE Study).Biomedicines · 2025Article
- Long-Term Brain-Computer Interface Functional Electrical Stimulation Enhances Neuroplasticity and Functional Recovery in Elderly Stroke: A 4.5-Year Longitudinal Study Integrating Electroencephalography Biomarkers and Clinical Assessments.Research (Washington, D.C.) · 2025Article
- Sex differences in stroke risk have changed: should we reconsider risk stratification?The Lancet regional health. Europe · 2024Article
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Female sex has been suggested as a risk modifier for stroke in patients with atrial fibrillation (AF) with comorbid prevalent stroke risk factors. Management has evolved over time towards a holistic approach that may have diminished any sex difference in AF-related stroke. In a nationwide cohort of AF patients free from oral anticoagulant treatment, we examine the time trends in stroke risk overall and in relation to risk differences between male and female patients. Here we show that among 158,982 patients with AF (median age 78 years (IQR: 71 to 85); 52% female) the 1-year thromboembolic risk was highest between 1997-2000 with a risk of 5.6% and lowest between 2013-2016 with a risk of 3.8%, declining over the last two decades. The excess stroke risk for female vs male patients has also been declining, with risk-score adjusted relative risk estimates suggesting limited sex-difference in recent years.
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