Evidence map›Paper›PMID 39112321›Full record

ArticleBrachytherapy

Commissioning considerations for the Bravos high-dose-rate afterloader: Towards improving treatment delivery accuracy.

Gil'ad N Cohen, Xiuxiu He, Michael Trager, Maria F Chan, Jeonghoon Park, Antonio L Damato, David Aramburu Nunez

Abstract read
In one paragraph

Article in Brachytherapy. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Gil'ad N CohenDepartment of Medical Physics, Memorial Sloan Kettering Cancer Center, New York, NY. Electronic address: gil'ad.cohen@nyulangone.org.
Xiuxiu HeDepartment of Medical Physics, Memorial Sloan Kettering Cancer Center, New York, NY.
Michael TragerDepartment of Medical Physics, Memorial Sloan Kettering Cancer Center, New York, NY.
Maria F ChanDepartment of Medical Physics, Memorial Sloan Kettering Cancer Center, Basking Ridge, NJ.
Jeonghoon ParkDepartment of Medical Physics, Memorial Sloan Kettering Cancer Center, Basking Ridge, NJ.
Antonio L DamatoDepartment of Medical Physics, Memorial Sloan Kettering Cancer Center, New York, NY.
David Aramburu NunezDepartment of Medical Physics, Memorial Sloan Kettering Cancer Center, New York, NY.

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Hongbiao Carl Lekaye · 1985 to 2026
$347.4M
NCI NIH HHS P30 CA008748
6 · The paper itself

Abstract

background and purposeThe upgrade of major equipment can be disruptive to clinical operations and introduce risk as policy and procedures need to adapt to new technical possibilities and constraints. We describe here the transition from GammaMedPlus-iX to Bravos in a busy brachytherapy clinic, involving four afterloaders across two sites. MATERIAL AND

methodsOur clinic employs three high-dose-rate remote afterloaders in four dedicated treatment vaults at the main site and a fourth afterloader at a regional location. Of more than 600 new HDR treatment plans performed annually, most are planned and treated intraoperatively. Most treatments are for prostate cancer, followed by GYN, intraoperative brachytherapy, GI, and other sites. Applicators used include vendor-provided applicators as well as third party applicators and in-house 3D-printed devices to provide interstitial, intracavitary, intraluminal, and surface treatments. All applicators were commissioned according to recommended guidelines. The choice of tolerances and the design of new procedures were informed by current guidelines and leveraged new HDR afterloader functionalities. A review of clinical operations in the 4 months postupgrade was conducted to evaluate the feasibility of new tolerances and the effectiveness of new procedures.

resultsThe procedures outlined improved and standardized afterloader QA and treatment protocols with clear actionable steps for staff to follow to ensure treatments are delivered as planned. Re-commissioning of applicators yielded results similar to those previously reported by other investigators. A review of initial treatment data revealed that in one case, due to the implementation of tight tolerances, obstruction near the tip of the channel was detected and corrected prior to treatment. It confirms that the implementation of the tolerances adopted is feasible and effective in flagging treatment deviations.

conclusionEnhanced procedures and QA processes were implemented successfully. We established clear actionable steps to follow by staff to ensure that treatments are delivered accurately.

Indexed as

BrachytherapyRadiotherapy DosageEquipment DesignFemaleHumansMaleProstatic NeoplasmsRadiotherapy Planning, Computer-AssistedEnhanced treatment verificationHigh dose rateQuality assurance

Identifiers

PMID39112321
PMCPMC12216218

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.