Evidence map›Paper›PMID 39112097›Full record

ArticleJournal of intellectual disability research : JIDR2024

Laboratory-based measures of executive function and daily living skills in young children with Down syndrome: informing future interventions.

K Van Deusen, M A Prince, M M Walsh, A J Esbensen, L R Patel, M E Pinks, A J Thurman, L Abbeduto, L A Daunhauer, D J Fidler

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of intellectual disability research : JIDR, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Cognitive Predictors of Adaptive Behaviour in Children With Down Syndrome: A Systematic Review.Journal of applied research in intellectual disabilities : JARID · 2026
    Pooled it
  2. Article
  3. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

K Van DeusenDepartment of Human Development and Family Studies, Colorado State University, Fort Collins, CO, USA.ORCID 0009-0008-2166-6166
M A PrinceDepartment of Human Development and Family Studies, Colorado State University, Fort Collins, CO, USA.
M M WalshDepartment of Human Development and Family Studies, Colorado State University, Fort Collins, CO, USA.
A J EsbensenDivision of Developmental and Behavioral Pediatrics, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.ORCID 0000-0003-2649-7791
L R PatelDepartment of Psychiatry, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.
M E PinksDepartment of Human Development and Family Studies, Colorado State University, Fort Collins, CO, USA.
A J ThurmanMIND Institute, University of California Davis, Sacramento, CA, USA.
L AbbedutoMIND Institute, University of California Davis, Sacramento, CA, USA.
L A DaunhauerDepartment of Human Development and Family Studies, Colorado State University, Fort Collins, CO, USA.
D J FidlerDepartment of Human Development and Family Studies, Colorado State University, Fort Collins, CO, USA.ORCID 0000-0001-6208-456X

Funding

Research Project: Pathologic Significance of Maternal AutoantibodiesP50HD103526 · NICHD · UNIVERSITY OF CALIFORNIA AT DAVIS · PI LEONARD J. ABBEDUTO, Melissa Dawn Bauman · 2020 to 2026
$9.7M
Executive Function Outcome Measures for Young Children with Down SyndromeR01HD099150 · NICHD · COLORADO STATE UNIVERSITY · PI DEBORAH J FIDLER · 2019 to 2026
$4.7M
Eunice Kennedy Shriver National Institute of Child Health and Human Development P50HD103526Eunice Kennedy Shriver National Institute of Child Health and Human Development R01HD099150NICHD NIH HHS P50 HD103526NICHD NIH HHS R01 HD099150
6 · The paper itself

Abstract

backgroundAdaptive behaviour refers to the practical skills necessary for independence and is considered a high-priority intervention target for children with neurogenetic conditions associated with intellectual disability, like Down syndrome (DS). Daily living skills (DLS) are a critical aspect of adaptive behaviour, but they have received little intervention attention, possibly because they involve a wide variety of skills across many settings. The present study aimed to advance DLS intervention science by examining the concurrent and longitudinal association between DLS performances and a cognitive skillset hypothesised to support DLS skill acquisition, executive function (EF).

methodsParticipants were 71 children with DS between the ages of 2.5 and 8.7 years (M = 5.23 years; standard deviation = 1.65) who completed a battery of adapted EF tasks and a primary caregiver who completed the Vineland Adaptive Behavior Scales 3rd Edition Parent/Caregiver Comprehensive Report Form. A subset of caregivers also provided 6- and 12-month follow-up adaptive behaviour information.

resultsResults demonstrated a positive association between EF task performance and DLS standard scores and v-scores both concurrently and longitudinally.

conclusionsThe findings have implications for potential future intervention approaches that aim to strengthen DLS performances by advancing EF skills in this population.

Indexed as

Activities of Daily LivingDown SyndromeExecutive FunctionAdaptation, PsychologicalChildChild, PreschoolFemaleHumansLongitudinal StudiesMaleadaptive behaviourclinical trialsDown syndromeexecutive functionsecondary endpoints

Identifiers

PMID39112097
PMCPMC11753510

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.