ArticleUltrasonography (Seoul, Korea)2024
Application of a quality threshold to improve liver shear wave elastography measurements in free-breathing pediatric patients.
Article in Ultrasonography (Seoul, Korea), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThis study assessed the benefits of quality threshold (QT) implementation for liver shear wave elastography (SWE) in children during free breathing.
methodsThe QT, which adjusts the SWE map display based on shear wave quality, was set at 55%. Phantom measurements (PMs) were taken with a fixed probe using QT (termed PM-1); a moving probe without QT (PM-2); and a moving probe with QT (PM-3). Each measurement was subjected to random samplings of various sizes. Clinical measurements (CMs) were obtained from children with biliary atresia using following protocols: CM-1, manually defined regions of interest (ROIs); CM-2, default ROIs without QT; and CM-3, default ROIs with QT. Elasticity measurements were compared across fibrosis grades, and color patterns on the SWE maps were analyzed.
resultsIn the phantom experiments, the moving probe produced lower elasticity measurements; this difference decreased upon QT application. With the moving probe, random sampling indicated fewer interquartile range-to-median ratios exceeding 30% upon QT application (4% vs. 14% when five values were sampled, P=0.004). In clinical experiments, QT improved the differentiation of fibrosis grade in patients over 5 years old, with a significant difference between moderate and severe fibrosis (P=0.004). Elasticity variability was positively correlated with fibrosis grade (τ=0.376, P<0.001). Certain apparent errors, termed artificial stripe patterns, were not eliminated by QT.
conclusionApplying QT to exclude low-quality pixels can minimize measurement error and improve differentiation of liver fibrosis grades. The presence of an artificial stripe pattern on the SWE map may indicate images requiring exclusion.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.