Evidence map›Paper›PMID 39111883›Full record

ArticleInternal medicine (Tokyo, Japan)2025

Neurosyphilis Presenting with Isolated Abducens Nerve Palsy.

Taiji Mukai, Keiichi Hokkoku, Takatoshi Kitazawa, Hiroshi Oba, Yuki Hatanaka, Masahiro Sonoo, Shunsuke Kobayashi

Abstract readCase Reports
In one paragraph

Article in Internal medicine (Tokyo, Japan), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Neurosyphilis presenting as ocular motor nerve palsy: two cases and a systematic literature review.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2026
    Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Taiji MukaiDepartment of Neurology, Teikyo University School of Medicine, Japan.
Keiichi HokkokuDepartment of Neurology, Teikyo University School of Medicine, Japan.
Takatoshi KitazawaDepartment of Neurology, Teikyo University School of Medicine, Japan.
Hiroshi ObaDepartment of Neurology, Teikyo University School of Medicine, Japan.
Yuki HatanakaDepartment of Neurology, Teikyo University School of Medicine, Japan.
Masahiro SonooDepartment of Neurology, Teikyo University School of Medicine, Japan.
Shunsuke KobayashiDepartment of Neurology, Teikyo University School of Medicine, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We herein report a case of neurosyphilis that presented with isolated bilateral abducens nerve palsy. A 39-year-old man was referred to our department with diplopia. He had a history of homosexual relationships and showed only bilateral abducens nerve palsy upon a neurological examination. Positive syphilis tests in the serum and cerebrospinal fluid and a contrasting effect on the abducens nerve on magnetic resonance imaging (MRI) confirmed the diagnosis of active neurosyphilis. When a patient manifests isolated abducens nerve palsy, neurosyphilis can be a differential diagnosis, although rare, and contrast-enhanced MRI may help diagnose the disease.

Indexed as

Abducens Nerve DiseasesNeurosyphilisAdultDiagnosis, DifferentialHumansMagnetic Resonance ImagingMalecranial nerve palsydiplopiaisolated abducens nerve palsymagnetic resonance imagingneurosyphilis

Identifiers

PMID39111883
PMCPMC11986314

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.