Evidence map›Paper›PMID 39111771›Full record

ArticleACS applied materials & interfaces2024

MXene-Polydopamine-antiCEACAM1 Antibody Complex as a Strategy for Targeted Ablation of Melanoma.

Anastasia Konieva, Volodymyr Deineka, Kateryna Diedkova, Daniel Aguilar-Ferrer, Mykola Lyndin, Gunther Wennemuth, Viktoriia Korniienko, Sergiy Kyrylenko, Alexey Lihachev, Veronika Zahorodna and 8 more

Abstract read
In one paragraph

Article in ACS applied materials & interfaces, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Anastasia KonievaDepartment of Anatomy, University Hospital Essen, Hufelandstraße 55, 45147 Essen, Germany.
Volodymyr DeinekaBiomedical Research Center, Medical Institute, Sumy State University, 31 Sanatornaya Str., 40018 Sumy, Ukraine.ORCID 0000-0002-9492-8170
Kateryna DiedkovaBiomedical Research Center, Medical Institute, Sumy State University, 31 Sanatornaya Str., 40018 Sumy, Ukraine.
Daniel Aguilar-FerrerNanoBioMedical Centre, Adam Mickiewicz University, 3, Wszechnicy Piastowskiej Str., 61-614 Poznan, Poland.
Mykola LyndinDepartment of Anatomy, University Hospital Essen, Hufelandstraße 55, 45147 Essen, Germany.ORCID 0000-0003-4385-3903
Gunther WennemuthDepartment of Anatomy, University Hospital Essen, Hufelandstraße 55, 45147 Essen, Germany.
Viktoriia KorniienkoBiomedical Research Center, Medical Institute, Sumy State University, 31 Sanatornaya Str., 40018 Sumy, Ukraine.
Sergiy KyrylenkoBiomedical Research Center, Medical Institute, Sumy State University, 31 Sanatornaya Str., 40018 Sumy, Ukraine.ORCID 0000-0002-4343-0065
Alexey LihachevInsitute of Atomic Physics and Spectroscopy, University of Latvia, 3 Jelgavas Str., LV-1004 Riga, Latvia.
Veronika ZahorodnaMaterials Research Centre, 3 Krzhizhanovskogo Str., 03142 Kyiv, Ukraine.ORCID 0000-0002-8873-015X
Ivan BaginskiyBiomedical Research Center, Medical Institute, Sumy State University, 31 Sanatornaya Str., 40018 Sumy, Ukraine.ORCID 0000-0002-0092-9018
Emerson CoyNanoBioMedical Centre, Adam Mickiewicz University, 3, Wszechnicy Piastowskiej Str., 61-614 Poznan, Poland.ORCID 0000-0002-4149-9720
Oleksiy GogotsiBiomedical Research Center, Medical Institute, Sumy State University, 31 Sanatornaya Str., 40018 Sumy, Ukraine.
Agata Blacha-GrzechnikFaculty of Chemistry, Silesian University of Technology, 9 Strzody Str., 44-100 Gliwice, Poland.
Wojciech SimkaFaculty of Chemistry, Silesian University of Technology, 9 Strzody Str., 44-100 Gliwice, Poland.ORCID 0000-0002-2648-5523
Irina Kube-GolovinDepartment of Anatomy, University Hospital Essen, Hufelandstraße 55, 45147 Essen, Germany.
Igor IatsunskyiNanoBioMedical Centre, Adam Mickiewicz University, 3, Wszechnicy Piastowskiej Str., 61-614 Poznan, Poland.
Maksym PogorielovBiomedical Research Center, Medical Institute, Sumy State University, 31 Sanatornaya Str., 40018 Sumy, Ukraine.ORCID 0000-0001-9372-7791

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Photothermal therapy (PTT) is a method for eradicating tumor tissues through the use of photothermal materials and photosensitizing agents that absorb light energy from laser sources and convert it into heat, which selectively targets and destroys cancer cells while sparing healthy tissue. MXenes have been intensively investigated as photosensitizing agents for PTT. However, achieving the selectivity of MXenes to the tumor cells remains a challenge. Specific antibodies (Ab) against tumor antigens can achieve homing of the photosensitizing agents toward tumor cells, but their immobilization on MXene received little attention. Here, we offer a strategy for the selective ablation of melanoma cells using MXene-polydopamine-antiCEACAM1 Ab complexes. We coated Ti

Indexed as

IndolesMelanomaPolymersAnimalsCarcinoembryonic AntigenCell Line, TumorHumansMicePhotosensitizing AgentsPhotothermal TherapyTitaniumCarcinoembryonic AntigenIndolesPhotosensitizing AgentspolydopaminePolymersTitaniumtitanium carbideantibody immobilizationanticancer therapyCEACAM1MXenephotothermal ablationtargeted delivery

Identifiers

PMID39111771
PMCPMC11345726

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.