Evidence map›Paper›PMID 39111691›Full record

ArticleThe Journal of thoracic and cardiovascular surgery2025

American Association for Thoracic Surgery Quality Gateway: A surgeon case study of its application in adult cardiac surgery for quality assurance.

Lars G Svensson, Eugene H Blackstone, Linda DiPaola, Benjamin P Kramer, Hemant Ishwaran

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Article in The Journal of thoracic and cardiovascular surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

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2citing papers in PubMed
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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

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4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

5 authors.

Lars G SvenssonDepartment of Thoracic and Cardiovascular Surgery, Cleveland Clinic, Cleveland, Ohio.
Eugene H BlackstoneDepartment of Thoracic and Cardiovascular Surgery, Cleveland Clinic, Cleveland, Ohio; Department of Quantitative Health Sciences, Cleveland Clinic, Cleveland, Ohio. Electronic address: blackse@ccf.org.
Linda DiPaolaDepartment of Quantitative Health Sciences, Cleveland Clinic, Cleveland, Ohio.
Benjamin P KramerDepartment of Thoracic and Cardiovascular Surgery, Cleveland Clinic, Cleveland, Ohio.
Hemant IshwaranDivision of Biostatistics, University of Miami, Miami, Fla.

Funding

Real time risk prognostication via scalable hazard trees and forestsR01HL164405 · NHLBI · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI Hemant Ishwaran · 2023 to 2026
$2.3M
Super Greedy TreesR35GM139659 · NIGMS · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI ISHWARAN, HEMANT · 2021 to 2025
$2.1M
NHLBI NIH HHS R01 HL164405NIGMS NIH HHS R35 GM139659
6 · The paper itself

Abstract

objectiveTo demonstrate the application of American Association for Thoracic Surgery Quality Gateway (AQG) outcomes models to a Surgeon Case Study of quality assurance in adult cardiac surgery.

methodsThe case study includes 6989 cardiac and thoracic aorta operations performed in adults at Cleveland Clinic by a single surgeon between 2001 and 2023. AQG models were used to predict expected probabilities for operative mortality and major morbidity and to compare hospital outcomes, surgery type, risk profile, and individual risk factor levels using virtual (digital) twin causal inference. These models were based on postoperative procedural outcomes after 52,792 cardiac operations performed in 19 hospitals of 3 high-performing hospital systems with overall hospital mortality of 2.0%, analyzed by advanced machine learning for rare events.

resultsFor individual surgeons, their patients, hospitals, and hospital systems, the Surgeon Case Study demonstrated that AQG provides expected outcomes across the entire spectrum of cardiac surgery, from single-component primary operations to complex multicomponent reoperations. Actionable opportunities for quality improvement based on virtual twins are illustrated for patients, surgeons, hospitals, risk profile groups, operations, and risk factors vis-à-vis other hospitals.

conclusionsUsing minimal data collection and models developed using advanced machine learning, this case study shows that probabilities can be generated for operative mortality and major morbidity after virtually all adult cardiac operations. It demonstrates the utility of 21st century causal inference (virtual [digital] twin) tools for assessing quality for surgeons asking "how am I doing?," their patients asking "what are my chances?," and the profession asking "how can we get better?"

Indexed as

Cardiac Surgical ProceduresQuality Assurance, Health CareQuality Indicators, Health CareAdultAgedFemaleHospital MortalityHumansMaleMiddle AgedPostoperative ComplicationsQuality ImprovementRisk AssessmentRisk FactorsSocieties, MedicalSurgeonscausal inferencedigital twinsmachine learningmorbiditymortalityrisk modelsvirtual twins

Identifiers

PMID39111691
PMCPMC13589287

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.