Evidence map›Paper›PMID 39110816›Full record

Observational studyRevista medica del Instituto Mexicano del Seguro Social2024

[Neutrophil-lymphocyte ratio as predictor of mortality in patients with necrotizing fasciitis].

Octavio Ávila-Mercado, Víctor Flores-Gamboa, José Manuel Reyes-Ruiz, Paola Campos-Hernández, Gustavo Martínez-Mier

Abstract readEnglish AbstractObservational Study
In one paragraph

Observational study in Revista medica del Instituto Mexicano del Seguro Social, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Octavio Ávila-MercadoInstituto Mexicano del Seguro Social, Centro Médico Nacional "Lic. Adolfo Ruiz Cortines", Hospital de Especialidades No. 14, Servicio de Cirugía General. Veracruz, Veracruz, México.ORCID 0000-0002-7187-4173
Víctor Flores-GamboaInstituto Mexicano del Seguro Social, Centro Médico Nacional "Lic. Adolfo Ruiz Cortines", Hospital de Especialidades No. 14, Servicio de Cirugía General. Veracruz, Veracruz, México.ORCID 0000-0001-5318-3021
José Manuel Reyes-RuizInstituto Mexicano del Seguro Social, Centro Médico Nacional "Lic. Adolfo Ruiz Cortines", Hospital de Especialidades No. 14, División de Investigación en Salud. Veracruz, Veracruz, México.ORCID 0000-0002-2379-8591
Paola Campos-HernándezInstituto Mexicano del Seguro Social, Centro Médico Nacional "Lic. Adolfo Ruiz Cortines", Hospital de Especialidades No. 14, Coordinación de Donación y Trasplante de Órganos. Veracruz, Veracruz, México.ORCID 0009-0009-9641-7276
Gustavo Martínez-MierInstituto Mexicano del Seguro Social, Centro Médico Nacional "Lic. Adolfo Ruiz Cortines", Hospital de Especialidades No. 14, División de Investigación en Salud. Veracruz, Veracruz, México.ORCID 0000-0002-2883-9188

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Necrotizing fasciitis (NF) can affect any soft tissue and skin of the body. Its progression is rapid and it is associated with a high mortality rate. Therefore, the search for easily accessible and low-cost biomarkers that could predict the prognosis of patients with NF is necessary. Objective: To evaluate the role of neutrophil-lymphocyte ratio (NLR) as a predictor of mortality in patients with NF. Material and methods: Observational, cross-sectional, retrospective and analytical study of patients admitted between April and October 2020 in a tertiary-care hospital. The statistical tests used for the comparison of variables between the study groups were chi-square, Fisher's exact, Student's t and Mann-Whitney U. A receiver operating characteristic (ROC) curve was performed to determine the accuracy of NLR in predicting mortality in patients with NF. Results: A total of 25 patients were included and stratified into non-survivors and survivors. The non-survivor group had an elevated NLR value compared to survivors (15.57 [13.75] vs. 7.91 [4.13]; p = 0.065). The NLR had an area under the curve (AUC) of 0.729 (95% confidence interval [95% CI] 0.516-0.886; p = 0.044), sensitivity of 77.78% (40-97.2), and specificity of 75% (47.6-92.7). The optimal cut-off point obtained for NLR was > 9.21. Conclusions: An NLR value > 9.21 could be a predictor of mortality in patients with NF.

Indexed as

Fasciitis, NecrotizingLymphocytesNeutrophilsAdultAgedBiomarkersCross-Sectional StudiesFemaleHumansLymphocyte CountMaleMiddle AgedPredictive Value of TestsPrognosisRetrospective StudiesROC CurveBiomarkersFasciitis, NecrotizingMortalityNeutrophil-Lymphocyte Ratio

Identifiers

PMID39110816
PMCPMC12101530

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.