Evidence map›Paper›PMID 39110539›Full record

ArticleRheumatology (Oxford, England)2025

Tendon involvement and its association with pain and hand function in patients with osteoarthritis of the hand.

Irina Gessl, Anna Vinatzer, Gabriela Supp, Michael Zauner, Martina Durechova, Lisa Lechner, Valentin Ritschl, Josef Smolen, Tanja Stamm, Daniel Aletaha and 1 more

Abstract read
In one paragraph

Article in Rheumatology (Oxford, England), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Irina GesslDivision of Rheumatology, Department of Internal Medicine III, Medical University of Vienna, Vienna, Austria.ORCID 0000-0001-6477-0117
Anna VinatzerDivision of Rheumatology, Department of Internal Medicine III, Medical University of Vienna, Vienna, Austria.
Gabriela SuppDivision of Rheumatology, Department of Internal Medicine III, Medical University of Vienna, Vienna, Austria.
Michael ZaunerDivision of Rheumatology, Department of Internal Medicine III, Medical University of Vienna, Vienna, Austria.
Martina DurechovaDivision of Rheumatology, Department of Internal Medicine III, Medical University of Vienna, Vienna, Austria.
Lisa LechnerDivision of Rheumatology, Department of Internal Medicine III, Medical University of Vienna, Vienna, Austria.
Valentin RitschlInstitute of Outcomes Research, Center for Medical Data Science, Medical University of Vienna, Vienna, Austria.ORCID 0000-0001-8763-8215
Josef SmolenDivision of Rheumatology, Department of Internal Medicine III, Medical University of Vienna, Vienna, Austria.
Tanja StammInstitute of Outcomes Research, Center for Medical Data Science, Medical University of Vienna, Vienna, Austria.ORCID 0000-0003-3073-7284
Daniel AletahaDivision of Rheumatology, Department of Internal Medicine III, Medical University of Vienna, Vienna, Austria.
Peter MandlDivision of Rheumatology, Department of Internal Medicine III, Medical University of Vienna, Vienna, Austria.

Funding

AbbVieAstraZenecaMayor of the City of Vienna 15213Medical Scientific Fund
6 · The paper itself

Abstract

objectiveTo characterize the frequency and influence of tenosynovitis and tendon damage on pain and hand function using clinical examination and US in hand OA.

methodsWe included 86 patients with hand OA and 23 age- and sex-matched control subjects. Extensor and flexor tendons of both hands were assessed by clinical examination and US for tenosynovitis and tendon damage. Conventional radiographs were acquired. Hand function was evaluated by the function subtest of the M-SACRAH (modified Score for the Assessment and Quantification of Chronic Rheumatoid Affections of the Hands) questionnaire and the Moberg pick-up test. K-means cluster analyses was calculated to assess clusters based on radiographic features and sonographic tendon scores.

resultsUS identified the involvement of one or more tendon in 60/86 (69.8%) hand OA patients compared with 2/23 (8.7%) subjects (P < 0.01) in the control group. In the hand OA group, US detected tendon damage more often in flexor tendons compared with extensor tendons (2.1% vs 0.9%, P = 0.03), while tenosynovitis was observed more often in extensor tendons compared with flexor tendons (8% vs 0.6%, P < 0001). The sensitivity and specificity of clinical examination to detect tendon involvement was 81.4% and 34.6%, respectively, on the patient level and 14.5% and 83.8% on the tendon level. The cluster analyses revealed one cluster with more radiographic features of hand OA and more tendon damage while more tenosynovitis was found in cluster 2. M-SACRAH function did not correlate with tendon involvement on US.

conclusionThis study revealed a high frequency of tendon involvement in hand OA. Tendon involvement on US did not impact hand function or self-reported pain.

Indexed as

HandHand JointsOsteoarthritisPainTendonsTenosynovitisAgedCase-Control StudiesFemaleHumansMaleMiddle AgedPain MeasurementRadiographyUltrasonographyhand osteoarthritismusculoskeletal ultrasoundosteophytespaintendon damagetenosynovitis

Identifiers

PMID39110539
PMCPMC11962883

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.