Evidence map›Paper›PMID 39110476›Full record

ArticleBriefings in bioinformatics2024

DeePhafier: a phage lifestyle classifier using a multilayer self-attention neural network combining protein information.

Yan Miao, Zhenyuan Sun, Chen Lin, Haoran Gu, Chenjing Ma, Yingjian Liang, Guohua Wang

Abstract read
In one paragraph

Article in Briefings in bioinformatics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Yan MiaoCollege of Computer and Control Engineering, Northeast Forestry University, No. 26 Hexing Road, Harbin, 150040, Heilongjiang, China.ORCID 0000-0001-7719-426X
Zhenyuan SunCollege of Computer and Control Engineering, Northeast Forestry University, No. 26 Hexing Road, Harbin, 150040, Heilongjiang, China.ORCID 0009-0004-7993-0194
Chen LinNational Institute for Data Science in Health and Medicine, Xiamen University, No. 4221 Xiangannan Road, Xiamen, 361102, Fujian, China.
Haoran GuCollege of Computer and Control Engineering, Northeast Forestry University, No. 26 Hexing Road, Harbin, 150040, Heilongjiang, China.
Chenjing MaCollege of Computer and Control Engineering, Northeast Forestry University, No. 26 Hexing Road, Harbin, 150040, Heilongjiang, China.
Yingjian LiangKey Laboratory of Hepatosplenic Surgery, Ministry of Education, Department of General Surgery, the First Affiliated Hospital of Harbin Medical University, No. 23 Postal Street, Harbin, 150007, Heilongjiang, China.
Guohua WangCollege of Computer and Control Engineering, Northeast Forestry University, No. 26 Hexing Road, Harbin, 150040, Heilongjiang, China.ORCID 0000-0001-7381-2374

Funding

Fundamental Research Funds for the Central Universities 62301139National Natural Science Foundation of China 62225109
6 · The paper itself

Abstract

Bacteriophages are the viruses that infect bacterial cells. They are the most diverse biological entities on earth and play important roles in microbiome. According to the phage lifestyle, phages can be divided into the virulent phages and the temperate phages. Classifying virulent and temperate phages is crucial for further understanding of the phage-host interactions. Although there are several methods designed for phage lifestyle classification, they merely either consider sequence features or gene features, leading to low accuracy. A new computational method, DeePhafier, is proposed to improve classification performance on phage lifestyle. Built by several multilayer self-attention neural networks, a global self-attention neural network, and being combined by protein features of the Position Specific Scoring Matrix matrix, DeePhafier improves the classification accuracy and outperforms two benchmark methods. The accuracy of DeePhafier on five-fold cross-validation is as high as 87.54% for sequences with length >2000bp.

Indexed as

BacteriophagesNeural Networks, ComputerAlgorithmsComputational BiologyViral ProteinsViral Proteinsmetagenomephage lifestyle classificationPSSM matrixself-attention network

Identifiers

PMID39110476
PMCPMC11304974

What OpenQuestion holds

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LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.