Evidence map›Paper›PMID 39110364›Full record

ArticleAging clinical and experimental research2024

Predictors of the onset of low handgrip strength in Europe: a longitudinal study of 42,183 older adults from 15 countries.

Rizwan Qaisar, M Azhar Hussain, Fabio Franzese, Asima Karim, Firdos Ahmad, Atif Awad, Abeer A Al-Masri, Shaea A Alkahtani

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In one paragraph

Article in Aging clinical and experimental research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Rizwan QaisarBasic Medical Sciences, College of Medicine, University of Sharjah, 27272, Sharjah, United Arab Emirates.
M Azhar HussainDepartment of Finance and Economics, College of Business Administration, University of Sharjah, 27272, Sharjah, United Arab Emirates.
Fabio FranzeseSHARE Berlin Institute, Chausseestraße 111, 10115, Berlin, Germany.
Asima KarimBasic Medical Sciences, College of Medicine, University of Sharjah, 27272, Sharjah, United Arab Emirates.
Firdos AhmadBasic Medical Sciences, College of Medicine, University of Sharjah, 27272, Sharjah, United Arab Emirates.
Atif AwadDepartment of Finance and Economics, College of Business Administration, University of Sharjah, 27272, Sharjah, United Arab Emirates.
Abeer A Al-MasriDepartment of Physiology, College of Medicine, King Saud University, 11451, Riyadh, Saudi Arabia.
Shaea A AlkahtaniExercise Physiology Department, College of Sport Sciences and Physical Activity, King Saud University, 11451, Riyadh, Saudi Arabia. shalkahtani@ksu.edu.sa.

Funding

Enhancing the Comparability of SHARE with HRS and ELSAR01AG052527 · NIA · MAX PLANCK INST/SOCIAL LAW/SOCIAL POLICY · PI BOERSCH-SUPAN, AXEL H · 2016 to 2020
$2.1M
NIA NIH HHS HHSN271201300071CNIA NIH HHS R01 AG052527The Researchers Supporting Project, King Saud University, Riyadh, Saudi Arabia RSP2024R277
6 · The paper itself

Abstract

objectivesA low handgrip strength (HGS) is a significant risk factor for multiple diseases. However, most relevant studies investigate the complications of a low HGS, while the risk potential of causative factors of low HGS remain poorly characterized.

methodsWe investigated the potentials of quality of life, depression, dyslipidaemia, diabetes mellitus, cancer, Alzheimer's disease, stroke, frailty, and difficulties performing daily activities in predicting low HGS (≤ 27 kg for men, ≤ 16 kg for women) in European older adults aged 50 or above from 15 countries (n = 42,183). All data was collected from four successive waves of survey of health, ageing, and retirement in Europe (SHARE) conducted between 2013 and 2020. Logistic models are applied, and estimated effects are presented as odds ratios and probabilities.

resultsCollectively, 3016 participants (men; n = 1395; 7.38%, women; n = 1621, 6.97%) developed low HGS during the 6.5 years study period. After adjusting for covariables, we identified an advancing age (1.6-48.1% points higher risk of low HGS), male gender (1.0%-point higher risk of low HGS), lower quality of life (1.6%-point higher), and stroke (1.5%-points) as significant risk factors for low HGS. We also found a dose-dependent association of Euro-D depression scores with the risk of low HGS, as the higher scores were associated with between 0.6- and 2.3%-points higher risk of developing low HGS than participants without depression. Among physical performance indicators, difficulty climbing stairs (2.0%-points higher low HGS risk) or rising from a chair (0.7%-points) were significantly associated with developing low HGS. Lastly, frailty (0.9%-points higher risk of low HGS) and the fear of falling down (1.6%-points higher risk) also increased the risk of developing low HGS.

conclusionAltogether, we report several risk factors for developing low HGS. Our observations may help evaluating and monitoring high-risk population for developing low HGS in pre-clinical settings.

Indexed as

Hand StrengthQuality of LifeActivities of Daily LivingAgedAged, 80 and overAgingEuropeFemaleFrailtyHumansLongitudinal StudiesMaleMiddle AgedRisk FactorsHandgrip strengthQuality of lifeRisk factorsSHARE data

Identifiers

PMID39110364
PMCPMC11306649

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.