Evidence map›Paper›PMID 39110332›Full record

GuidelineWorld journal of pediatrics : WJP2024

Guidelines for the diagnosis and treatment of neurally mediated syncope in children and adolescents (revised 2024).

Cheng Wang, Ying Liao, Shuo Wang, Hong Tian, Min Huang, Xiang-Yu Dong, Lin Shi, Ya-Qi Li, Jing-Hui Sun, Jun-Bao Du and 2 more

Abstract readPractice GuidelineReview
In one paragraph

Guideline in World journal of pediatrics : WJP, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed.

  1. Article
  2. Volumetric analysis of thalamic nuclei in children with vasovagal syncope.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2026
    Article
  3. Article
  4. Difference in clinical characteristics between functional syncope and vasovagal syncope in children.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2026
    Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Co-segregation ofFrontiers in pediatrics · 2026
    Article
  10. Article
  11. [How I treat vasovagal syncope in children].Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2025
    Article
  12. Clinical evaluation and risk factors of head-up tilt test in children.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2025
    Review
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Review
  19. Malignant vasovagal syncope in children.World journal of pediatrics : WJP · 2025
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Cheng WangDepartment of Pediatric Cardiovasoloy, Children's Medical Center, The Second Xiangya Hospital, Central South University, Changsha, 410011, China.
Ying LiaoDepartment of Pediatrics, Peking University First Hospital, Beijing, 100034, China.
Shuo WangDepartment of Pediatrics, Xiangya Hospital, Central South University, Changsha, 410008, China.
Hong TianDepartment of Pediatric Cardiology, Children's Hospital of Fudan University, Shanghai, 201102, China.
Min HuangDepartment of Pediatric Cardiology, Shanghai Children's Hospital, Shanghai, 201102, China.
Xiang-Yu DongDepartment of Pediatrics, Lanzhou University Second Hospital, Lanzhou, 730020, China.
Lin ShiDepartment of Pediatric Cardiology, Capital Institute of Pediatrics, Beijing, 100020, China.
Ya-Qi LiDepartment of Pediatric Cardiology, Capital Institute of Pediatrics, Beijing, 100020, China.
Jing-Hui SunDepartment of Pediatrics, Jilin University First Hospital, Changchun, 130021, China.
Jun-Bao DuDepartment of Pediatrics, Peking University First Hospital, Beijing, 100034, China. junbaodu1@126.com.
Hong-Fang JinDepartment of Pediatrics, Peking University First Hospital, Beijing, 100034, China. jinhongfang51@126.com.
Chinese Pediatric Cardiology Society, Chinese Pediatric Society, Chinese Medical Association; Committee of Pediatric Syncope, College of Pediatricians, Chinese Medical Doctor Association; Pediatric Cardiology Society, Beijing Pediatric Society, Beijing Medical Association; Committee of Pediatric Cardiology, College of Cardiovascular Physicians, Chinese Medical Doctor Association

Funding

National High-Level Hospital Clinical Research Funding 2022CR59
6 · The paper itself

Abstract

backgroundSignificant progress has been made in the diagnosis and treatment of pediatric syncope since the publication of the "2018 Chinese Pediatric Cardiology Society (CPCS) guideline for diagnosis and treatment of syncope in children and adolescents" ("2018 Edition Guidelines"). Therefore, we have revised and updated it to assist pediatricians in effectively managing children with syncope. DATA SOURCES: According to the "2018 Edition Guidelines", the expert groups collected clinical evidence, evaluated preliminary recommendations, and then organized open-ended discussions to form the recommendations. This guideline was developed by reviewing the literature and studies in databases including PubMed, Cochrane, EMBASE, China Biomedical Database, and Chinese Journal Full-text Database up to April 2024. Search terms included "syncope", "children", "adolescents", "diagnosis", and "treatment."

resultsThe guidelines were based on the latest global research progress and were evidence-based. The classification of syncope etiology, diagnostic procedures, postural tests, such as the active standing test, head-up tilt test, and active sitting test, clinical diagnosis, and individualized treatment for neurally mediated syncope in pediatric population were included.

conclusionsThe guidelines were updated based on the latest literature. The concepts of sitting tachycardia syndrome and sitting hypertension were introduced and the comorbidities of neurally mediated syncope were emphasized. Some biomarkers used for individualized treatment were underlined. Specific suggestions were put forward for non-pharmacological therapies as well as the follow-up process. The new guidelines will provide comprehensive guidance and reference for the diagnosis and treatment of neurally mediated syncope in children and adolescents.

Indexed as

Syncope, VasovagalAdolescentChildHumansAdolescentsChildrenDiagnosisNeurally mediated syncopeTreatment

Identifiers

PMID39110332
PMCPMC11502568

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.