ArticleApplied biochemistry and biotechnology2025
In Vitro and In Vivo Evaluation of Electrospun PVA Nanofiber Containing ZnO/Curcumin for Wound Healing Application.
Article in Applied biochemistry and biotechnology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed.
- Poly(Lactic Acid) Nanofiber Membrane Loaded with Tannins from Charred Sanguisorbae Radix with Antioxidant and Antibacterial Activities for Potential Wound Healing Applications.Applied biochemistry and biotechnology · 2026Article
- Chitosan/reduced graphene oxide/papain nanocomposite: a bioactive platform for skincare and biomedical applications.Scientific reports · 2026Article
- Chitosan-EDTA-cellulose functionalized with β-cyclodextrin as a pH-sensitive bio-based nanocarrier for curcumin drug delivery.Scientific reports · 2026Article
- Expanded Nanofibrous Polymeric Mats Incorporating Tetracycline-Loaded Silica Mesoporous Nanoparticles for Antimicrobial Applications.Pharmaceutics · 2025Article
- Zinc-integrated PLGA/chitosan nanofiber mesh: a platform for wound healing applications.RSC advances · 2025Article
- Formulation and Evaluation of Licorice-Extract-Enhanced Chitosan, PVA, and Gelatin-Derived Hydrogels for Wound Dressing.Bioengineering (Basel, Switzerland) · 2025Article
- Curcumin-Functionalized Electrospun Nanofibrous Membranes with Antimicrobial Activity for Wound Healing.Nanomaterials (Basel, Switzerland) · 2025Article
- Curcumin: a potential anti-photoaging agent.Frontiers in pharmacology · 2025Review
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The development of biocompatible wound dressings containing therapeutic agents to accelerate wound healing is an interesting field of study in biomedical sciences. Polyvinyl alcohol (PVA) nanofibers were loaded with zinc oxide nanoparticles (ZnO NPs) and curcumin (Cur) through electrospinning. The dressings were characterized by SEM and XRD and FTIR. The antioxidant, antibacterial, and cytotoxic activities Cur/ZnO/PVA nano dressing were evaluated using DPPH radical scavenging assay, disc diffusion method, and MTT assay, respectively. Cur/ZnO/PVA nano dressing showed sustained Cur release about 19.7% and 61.1% after 8h and 168h, respectively. Cur/ZnO NPs/PVA mixture had higher antioxidant potential than PVA, ZnO NPs, and Cur. The dressing showed a good antibacterial effect. The in vivo wound healing effect of different types of prepared dressings, including PVA, Cur/PVA, Cur/ZnO/PVA, and ZnO/ PVA nanofibers, was also investigated. PVA dressing containing Cur/ZnO NPs resulted in the highest increase of wound contraction in rats. The assembly of Cur and ZnO NPs on PVA nanofibers could propose as an effective delivery method to improve the wound healing process. The investigated wound dressing could be commercialized and used on a large scale after proper further studies, including clinical trials.
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