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ArticleWorld journal of urology2024

Does concordance between preoperatively measured prostate volume and enucleated weight predict outcomes in endoscopic enucleation of the prostate? Results from the REAP database.

Khi Yung Fong, Vineet Gauhar, Daniele Castellani, Ee Jean Lim, Mario Sofer, Dmitry Enikeev, Fernando Gómez Sancha, Jeremy Teoh, Bhaskar Somani, Thomas Herrmann

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Article in World journal of urology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

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3citing papers in PubMed
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1 · What the graph read from it

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3 · Its place in the literature

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3 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

10 authors.

Khi Yung FongYong Loo Lin School of Medicine, National University of Singapore, 10 Medical Dr, 117597, Singapore. khiyung@gmail.com.ORCID http://orcid.org/0000-0001-8194-0800
Vineet GauharDepartment of Urology, Ng Teng Fong General Hospital, Jurong East, Singapore.
Daniele CastellaniUrology Unit, Azienda Ospedaliero-Universitaria delle Marche, Università Politecnica delle Marche, Ancona, Italy.
Ee Jean LimDepartment of Urology, Singapore General Hospital, Outram Road, Singapore.
Mario SoferDepartment of Urology, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel.
Dmitry EnikeevInstitute for Urology and Reproductive Health, Sechenov University, Moscow, Russian Federation.
Fernando Gómez SanchaDepartment of Urology and Robotic Surgery, ICUA-Clínica CEMTRO, Madrid, Spain.
Jeremy TeohS.H. Ho Urology Centre, Department of Surgery, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong, China.
Bhaskar SomaniDepartment of Urology, University Hospitals Southampton, NHS Trust, Southampton, UK.
Thomas HerrmannDepartment of Urology, Kantonspital Frauenfeld, Spital Thurgau AG, Frauenfeld, Switzerland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundWe aimed to determine if preoperative prostate volume-enucleated weight concordance predicts short-term anatomical endoscopic enucleation of the prostate (AEEP) outcomes using the REAP international database.

methods649 patients with data on both preoperative ultrasound-derived prostate volume and enucleated specimen weight were analyzed. Linear regression was used to investigate the effect of volume-weight concordance on postoperative outcomes. Model residuals were used to divide the cohort into 3 centiles: (1) less-than-expected enucleated specimen weight; (2) appropriate concordance between prostate volume and specimen weight; (3) more-than-expected specimen weight. Outcomes were also analyzed with only enucleated weight as a predictor (comparing ≤ 80 g and > 80 g).

resultsThere was a trend towards more-than-expected enucleated specimen weight with increased age (p = 0.006). There was an increasing trend of operation time (p = 0.012) and enucleation time (p = 0.015) as specimen weight increased, and a decreasing trend of postoperative acute urinary retention (p = 0.005). Laser type, enucleation method, and early apical release were similar. In correlation analysis, greater-than-expected prostate weight was associated with greater Qmax improvement at 3 months. Prostate weight alone did not appear to be a significant predictor of outcomes.

conclusionsIf enucleated specimen weight is more than expected according to preoperative ultrasound volume measurement, greater Qmax improvement and less postoperative acute urinary retention is expected. Although precision may be limited by ultrasound approximation and inexact specimen weight measurements, these shortcomings are similar in real-world clinical practice. Overall, preoperative prostate volume and actual enucleated specimen weight should be interpreted in the context of each other to predict clinical outcomes.

Indexed as

Databases, FactualEndoscopyProstateProstatic HyperplasiaAgedHumansMaleMiddle AgedOrgan SizePreoperative PeriodProstatectomyRetrospective StudiesTreatment Outcome

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.