ArticleCardiovascular and interventional radiology2024
Large-bore Aspiration Thrombectomy with the FlowTriever System for the Treatment of Pulmonary Embolism: A Large Single-Center Retrospective Analysis.
Article in Cardiovascular and interventional radiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed.
- Invasive Management for Acute-on-Chronic Thromboembolic Pulmonary Hypertension: Feasibility and Clinical Outcomes in a Single-Center Cohort.Pulmonary circulation · 2026Article
- Procedure-Related Mortality in Aspiration Thrombectomy for Pulmonary Embolism: A MAUDE Database Analysis of the Inari FlowTriever and Penumbra Indigo Systems.Journal of endovascular therapy : an official journal of the International Society of Endovascular Specialists · 2026Article
- Case report of percutaneous intervention for extensive thrombosis after the Fontan procedure in a 14-year-old.European heart journal. Case reports · 2026Article
- Complications of catheter-directed interventions in acute pulmonary embolism: a narrative expert review with guidance on management.Cardiovascular diagnosis and therapy · 2026Review
- Setting Realistic Expectations in Pulmonary Embolism Therapy with Aspiration Thrombectomy: Insights from Real-World Data.Cardiovascular and interventional radiology · 2025Article
- Large-bore aspiration thrombectomy for the treatment of pulmonary embolism in octogenarians.CVIR endovascular · 2025Article
- Importance of Pulmonary Embolism Anatomy in Ventilatory Distress and Haemodynamics.Interventional cardiology (London, England) · 2025Review
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Authors and funding
5 authors.
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Abstract
purposeEvaluate the outcomes of patients undergoing large-bore aspiration thrombectomy for the treatment of pulmonary embolism at a large university medical center. MATERIALS AND
methodsAll patients treated for pulmonary embolism with the FlowTriever System (Inari Medical, Irvine, CA) between September 2019 and January 2023 were retrospectively analyzed. The primary safety and effectiveness outcomes included 7- and 30-day all-cause mortality, major bleeding, procedure-associated clinical decompensation, pulmonary vascular or cardiac injury, and pulmonary artery pressure reduction. Additional outcomes included technical success (completing thrombectomy with the device as intended), changes in hemodynamics and supplemental oxygen requirements, and postprocedural intensive care unit stay.
resultsA total of 286 patients were identified. The mean age was 60.5 years, and 90.9% of patients presented with intermediate-risk pulmonary embolism. Technical success was achieved in 96.9% (n = 277) of cases. The average reduction in mean pulmonary arterial pressure was 6.8 mmHg, from 28.7 ± 9.0 to 21.9 ± 8.0 mmHg (p < 0.0001). Two major bleeds (0.7%), 2 pulmonary vascular injuries (0.7%), and 4 (1.4%) procedure-associated decompensations were reported, but no device-related deaths occurred. The mean post-procedure intensive care unit stay was 2.0 ± 4.1 days, and 49.3% of patients had no postprocedural intensive care unit admittance. The overall 7-day and 30-day all-cause mortality rates were 2.4% and 6.7%, respectively, with a 30-day pulmonary embolism-related mortality rate of 3.5%.
conclusionThis non-industry-sponsored single-center analysis of large-bore aspiration thrombectomy in a large population corroborates the findings of other studies and confirms that this approach is safe and effective for the treatment high- and intermediate-risk pulmonary embolism. LEVEL OF EVIDENCE IV: Retrospective observational study.
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