Evidence map›Paper›PMID 39109734›Full record

ArticleArquivos brasileiros de oftalmologia2024

Night-time blood pressure dipping, but not 24-h blood pressure level, is linked to increased 24-h ocular volume slope.

Janusz Skrzypecki, F M Szymański, J Przybek-Skrzypecka, Justyna Izdebska, A Ryś-Czaporowska, K J Filipiak, Jacek P Szaflik

Abstract read
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Article in Arquivos brasileiros de oftalmologia, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Janusz SkrzypeckiDepartment of Experimental Physiology and Pathophysiology, Laboratory of Centre for Preclinical Research, Medical University of Warsaw, Warsaw, Poland.ORCID 0000-0002-6054-163X
F M SzymańskiDepartment of Civilization Diseases, Faculty of Medicine, Collegium Medicum, Stefan Cardinal Wyszynski University in Warsaw, Warszawa, Poland.
J Przybek-SkrzypeckaDepartment of Ophthalmology, SPKSO Ophthalmic Hospital, Medical University of Warsaw, Warsaw, Poland.
Justyna IzdebskaDepartment of Ophthalmology, SPKSO Ophthalmic Hospital, Medical University of Warsaw, Warsaw, Poland.
A Ryś-CzaporowskaDepartment of Civilization Diseases, Faculty of Medicine, Collegium Medicum, Stefan Cardinal Wyszynski University in Warsaw, Warszawa, Poland.
K J FilipiakInstitute of Clinical Sciences, Maria Sklodowska-Curie Medical Academy, Warszawa, Poland.
Jacek P SzaflikDepartment of Ophthalmology, SPKSO Ophthalmic Hospital, Medical University of Warsaw, Warsaw, Poland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThis study investigated the relationship between blood pressure and intraocular pressure in treatmentnaive, non-glaucoma patients with different blood pressure statuses, focusing on the 24-h ocular volume and nocturnal blood pressure decline.

methodsTreatment-naive, non-glaucoma patients undergoing hypertension evaluation were enrolled as study participants. Simultaneous 24-h ambulatory blood pressure measurement and 24-h ocular volume recording with a contact lens sensor. We also compared ocular volume curve parameters between normotensive and hypertensive patients, as well as between those with and without nocturnal blood pressure decline.

resultsA total of 21 patients, including 7 normotensive and 14 treatment-naive hypertensive individuals, were included in the study. of them, 11 were dippers and 10 were non-dippers. No significant difference in the 24-h ocular volume slope was observed between the hypertensive and normotensive patients (p=0.284). However, dippers had a significantly higher 24-h ocular volume slope (p=0.004) and nocturnal contact lens sensor output (p=0.041) than non-dippers.

conclusionNocturnal blood pressure decline, rather than the blood pressure level, is associated with the increased 24-h ocular volume slope and nocturnal ocular volume. Further studies are required to determine whether the acceleration of glaucoma progression in dippers is primarily due to low blood pressure, high intraocular pressure, or a combination of both.

Indexed as

Blood PressureBlood Pressure Monitoring, AmbulatoryCircadian RhythmHypertensionIntraocular PressureAdultCase-Control StudiesFemaleHumansMaleMiddle AgedReference ValuesTime FactorsTonometry, Ocular

Identifiers

PMID39109734
PMCPMC12585022

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