Evidence map›Paper›PMID 39109621›Full record

ArticleBrain tumor research and treatment2024

Malignant Transformation of Meningioma With

Yoontae Hong, Nayoung Han, Ho-Shin Gwak

Abstract readCase Reports
In one paragraph

Article in Brain tumor research and treatment, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Yoontae HongDepartment of Neurosurgery, Seoul National University College of Medicine, Seoul, Korea.ORCID https://orcid.org/0009-0006-8054-595X
Nayoung HanDepartment of Pathology, National Cancer Center, Goyang, Korea.
Ho-Shin GwakDepartment of Cancer Control, National Cancer Center, Graduate School of Cancer Science and Policy, Goyang, Korea. nsghs@ncc.re.kr.ORCID https://orcid.org/0000-0001-7175-4553

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

High-grade meningiomas make up a relatively minor proportion of meningiomas, which are one of the most common types of primary intracranial tumors in adults. Though rare, a considerable portion of high-grade meningiomas arise from malignant transformation of benign meningiomas. The 2021 World Health Organization (WHO) classification criteria introduced molecular markers in the diagnosis and grading of central nervous system (CNS) tumors and assigned certain genomic mutations to grade 3 meningiomas. We report a case of a 54-year-old male patient who underwent stepwise malignant transformation of meningioma from WHO grade 1 to grade 3 within 10 years, during the course of five surgeries followed by adjuvant stereotactic radiosurgery and radiotherapy. We performed next-generation sequencing (NGS) on the most recent grade 3 meningioma specimen and found that it carried a telomerase reverse transcriptase promoter (

Indexed as

GenomicsMeningiomaMutationRadiationRecurrenceTelomerase

Identifiers

PMID39109621
PMCPMC11306841

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.