Evidence map›Paper›PMID 39109527›Full record

ArticleEpigenetics2024

GGNBP2 regulates histone ubiquitination and methylation in spermatogenesis.

Kaimin Guo, Yin Cao, Zhiyi Zhao, Jiantao Zhao, Lingyun Liu, Hongliang Wang

Abstract read
In one paragraph

Article in Epigenetics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. mJournal of assisted reproduction and genetics · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Kaimin GuoDepartment of Andrology, First hospital of Jilin University, Changchun, China.
Yin CaoDepartment of Andrology, First hospital of Jilin University, Changchun, China.
Zhiyi ZhaoDepartment of Andrology, First hospital of Jilin University, Changchun, China.
Jiantao ZhaoDepartment of Andrology, First hospital of Jilin University, Changchun, China.
Lingyun LiuDepartment of Andrology, First hospital of Jilin University, Changchun, China.
Hongliang WangDepartment of Andrology, First hospital of Jilin University, Changchun, China.ORCID 0000-0002-1941-3003

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Gametogenetin binding protein 2 (GGNBP2) was indispensable in normal spermatids for transformation into mature spermatozoa in mice, and when Gametogenetin binding protein 2 is bound to BRCC36 and RAD51, the complex participates in repairing DNA double-strand breaks (DSB) during the meiotic progression of spermatocytes. Ggnbp2 knockout resulted in the up-regulation of H2A

Indexed as

HistonesSpermatogenesisUbiquitinationAdaptor Proteins, Signal TransducingAnimalsCell LineMaleMethylationMiceMice, KnockoutRepressor ProteinsTumor Suppressor ProteinsUbiquitin ThiolesteraseAdaptor Proteins, Signal TransducingGGNBP2 protein, mouseHistonesRepressor ProteinsTumor Suppressor ProteinsUbiquitin ThiolesteraseDNA repairGGNBP2H2A ubiquitinationH2B ubiquitinationhistone modificationspermatogenesis

Identifiers

PMID39109527
PMCPMC11734887

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.