Evidence map›Paper›PMID 39109500›Full record

ArticleKorean journal of radiology2024

Comparison of Chemoembolization Outcomes Using 70-150 µm and 100-300 µm Drug-Eluting Beads in Treating Small Hepatocellular Carcinoma: A Korean Multicenter Study.

Byung Chan Lee, Gyoung Min Kim, Juil Park, Jin Wook Chung, Jin Woo Choi, Ho Jong Chun, Jung Suk Oh, Dong Ho Hyun, Jung Ho Yang

Abstract readMulticenter StudyComparative Study
In one paragraph

Article in Korean journal of radiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Byung Chan LeeDepartment of Radiology, Chonnam National University Medical School, Chonnam National University Hwasun Hospital, Hwasun, Republic of Korea.ORCID 0000-0002-5940-9359
Gyoung Min KimDepartment of Radiology, Severance Hospital, Yonsei University College of Medicine, Seoul, Republic of Korea. kimgm@yonsei.ac.kr.ORCID 0000-0001-6768-4396
Juil ParkDepartment of Radiology, Severance Hospital, Yonsei University College of Medicine, Seoul, Republic of Korea.ORCID 0000-0002-5265-8723
Jin Wook ChungDepartment of Radiology, Seoul National University College of Medicine, Seoul National University Hospital, Seoul, Republic of Korea.ORCID 0000-0002-1090-6872
Jin Woo ChoiDepartment of Radiology, Seoul National University College of Medicine, Seoul National University Hospital, Seoul, Republic of Korea.ORCID 0000-0002-6639-8002
Ho Jong ChunDepartment of Radiology, Seoul St. Mary's Hospital, The Catholic University of Korea, Seoul, Republic of Korea.ORCID 0000-0003-4512-6152
Jung Suk OhDepartment of Radiology, Seoul St. Mary's Hospital, The Catholic University of Korea, Seoul, Republic of Korea.ORCID 0000-0001-6239-9457
Dong Ho HyunDepartment of Radiology, Samsung Medical Center, Sungkyunkwan University College of Medicine, Seoul, Republic of Korea.ORCID 0000-0002-2654-7202
Jung Ho YangDepartment of Preventive Medicine, Chonnam National University Medical School, Chonnam National University Hospital Cardio-Cerebrovascular Center, Gwangju, Republic of Korea.ORCID 0000-0002-1581-8425

Funding

Korean Society of Interventional Radiology
6 · The paper itself

Abstract

objectiveTo evaluate the outcomes of drug-eluting bead transarterial chemoembolization (DEB-TACE) according to the size of the beads for the treatment of small hepatocellular carcinoma (HCC). MATERIALS AND

methodsThis retrospective study included 212 patients with a single HCC ≤5 cm from five tertiary institutions. One hundred and nine patients were treated with 70-150-µm doxorubicin DEBs (group A), and 103 patients received 100-300-µm doxorubicin DEBs (group B). The initial tumor response (assessed between 3 weeks and 2 months after DEB-TACE), time to local tumor progression (TTLTP), restricted mean duration of complete response (RMDCR), rate of complications, incidence of post-embolization syndrome, and length of hospital stay were compared between the two groups. Logistic regression was used to analyze prognostic factors for initial tumor response.

resultsThe initial objective response rates were 91.7% (100/109) and 84.5% (87/103) for groups A and B, respectively (

conclusionDEB-TACE using 70-150-µm microspheres demonstrated a higher initial objective response rate in ≤3-cm HCCs and a longer RMDCR at 24 months in 3.1-5-cm HCCs compared to larger DEBs (100-300-µm).

Indexed as

Antibiotics, AntineoplasticCarcinoma, HepatocellularChemoembolization, TherapeuticDoxorubicinLiver NeoplasmsAdultAgedFemaleHumansMaleMicrospheresMiddle AgedRepublic of KoreaRetrospective StudiesTreatment OutcomeAntibiotics, AntineoplasticDoxorubicinChemoembolizationDrug-eluting beadHepatocellular carcinoma

Identifiers

PMID39109500
PMCPMC11306003

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.