ArticleIDCases2024
Primary amebic meningoencephalitis in children: A case report and literature review.
Article in IDCases, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed.
- Global Review onInfectious disease reports · 2026Review
- Immunological and inflammatory responses in the kidneys in experimental acanthamoebiasis.Microbiology spectrum · 2025Article
- A review of the mechanism, diagnosis, and treatment ofFrontiers in microbiology · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This article presents the diagnostic and therapeutic journey of a 14-year-old male patient diagnosed with Primary Amebic Meningoencephalitis (PAM), incorporates a review of pertinent literature and a discussion on recent advancements in the study of this condition. The patient presented with symptoms of fever and headache for three days, accompanied by seizures and a half-day episode of altered consciousness. Upon admission, clinical findings included a mild coma, respiratory distress, rigidity of limbs, and negative pathological reflexes. The patient's history showed in a local outdoor pond swimming in July and August of the same year. Metagenomic Next-Generation Sequencing (mNGS) of the cerebrospinal fluid identified the presence of Naegleria fowleri. Cranial CT and MRI scans indicated signs of brain edema and meningitis. The patient was confirmed with pediatric primary amebic meningoencephalitis. A 45-day comprehensive treatment regimen was administered, encompassing anti-amebic medications, anticonvulsant therapy, management of brain edema, and intracranial pressure reduction. This case represents the longest survival period recorded for such pediatric cases in China. The purpose of this report is to heighten clinical awareness of PAM, share diagnostic and therapeutic insights, expand upon existing treatment approaches, and ultimately contribute to improving the survival rates of PAM patients.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.