ArticleWorld journal of clinical cases2024
Glucocorticoid therapy in pancreatic portal hypertension associated with autoimmune pancreatitis: A case report.
Article in World journal of clinical cases, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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Who cites it
2 citing papers in PubMed.
- Multifocal autoimmune pancreatitis complicated by pancreatic insufficiency and segmental portal hypertension: A case report and review of the literature.Radiology case reports · 2026Article
- The dual role of endoscopic ultrasonography in the diagnosis and treatment of autoimmune pancreatitis with gastric variceal bleeding: A case report and literature review.The Journal of international medical research · 2025Review
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6 authors.
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Abstract
backgroundAutoimmune pancreatitis (AIP) is a chronic form of pancreatitis characterized by diffused enlargement of the pancreas and irregular stenosis of the main pancreatic duct. Some studies have reported that AIP can cause hemorrhage of gastric varices (GV) related to portal hypertension (PH). However, such cases are rare. In addition, the association of PH with AIP is unclear. At the same time, the efficacy and duration of glucocorticoid therapy is also controversial. CASE SUMMARY: In this case, we reported a case of GV in pancreatic PH associated with AIP. Enhanced abdominal computed tomography (CT) suggested splenic vein (SV) and superior mesenteric vein (SMV) thromboses. The patient received a long-term glucocorticoid therapy, that the initial dose of 40 mg is reduced weekly by 5 mg, and then reduced to 5 mg for long-term maintenance. CT and gastroscopic examination after 8 mo of treatment indicated that SV and SMV were recanalized, pancreatic stiffness and swelling were ameliorated, and the GV almost completely disappeared.
conclusionLong-term glucocorticoid therapy can alleviate the development of GV in patients with AIP and has potential reversibility.
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