Linear morphea distributed along radial nerve with high incidence of neuromusculoskeletal disorders: A single-center case series.

Xiuyuan Wang, Xue Han, Feifei Hu, Xinzhi Xu, Junxia Huang, Ji Yang

Abstract readCase Reports

In one paragraph

Article in Heliyon, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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1citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

Combination of Oral Hydroxychloroquine and Topical Pimecrolimus 1% for Linear Morphea in Breastfeeding: A Rare Case with Favorable Outcome.International journal of women's health · 2025
Article

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5 · Who and what money

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6 authors.

Xiuyuan WangDepartment of Dermatology, Zhongshan Hospital, Fudan University, Shanghai, 200032, China.

Xue HanDepartment of Dermatology, Zhongshan Hospital, Fudan University, Shanghai, 200032, China.

Feifei HuDepartment of Dermatology, Zhongshan Hospital, Fudan University, Shanghai, 200032, China.

Xinzhi XuDepartment of Dermatology, Zhongshan Hospital, Fudan University, Shanghai, 200032, China.

Junxia HuangDepartment of Dermatology, Zhongshan Hospital, Fudan University, Shanghai, 200032, China.

Ji YangDepartment of Dermatology, Zhongshan Hospital, Fudan University, Shanghai, 200032, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Linear morphea is the most disabling subtype of morphea, which may cause a series of excutaneous manifestations and sequelae. To futher explore the clinical characteristics of linear morphea, we conducted a retrospective study of 22 patients diagnosed with linear morphea in our department during the past 2 years. Their baseline clinical information, skin manifestations, complications and therapeutic effect were analyzed. Here, we report six cases of a special linear morphea, usually occurring on the unilateral upper limbs of young women, spreading along the distribution of the radial nerve and frequently progressing across the joint, which increases the incidence of neuromusculoskeletal disorders. Instead of traditional topical drugs, a combination of systemic prednisone and methotrexate improved their skin lesions and complications. Recognition of this special type of linear morphea enables earlier diagnosis and active treatment plan, which contributes to ameliorate the symptoms and avoid functional sequelae.

Indexed as

Clinical manifestationsLinear morpheaMorpheaRadial nerveTherapy

Identifiers

PMID39108918

DOI10.1016/j.heliyon.2024.e34398

PMCPMC11301347

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