Evidence map›Paper›PMID 39108752›Full record

ArticleFrontiers in pharmacology2024

Cystathionine γ-lyase inhibits mitochondrial oxidative stress by releasing H

Tingting Xiao, Shun Chen, Ge Yan, Junmin Zheng, Qingzhu Qiu, Shujia Lin, Yanfang Zong, Haishuang Chang, Alex Chia Yu Chang, Ying Wu and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in pharmacology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Cystathionine γ lyase deletion enhances corpus cavernosum contraction via thromboxane AAmerican journal of physiology. Regulatory, integrative and comparative physiology · 2025
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Tingting Xiao *Department of Cardiology, Shanghai Children's Hospital, School of Medicine, Shanghai Jiao Tong University, Pediatric Allergy and Immune Disease Laboratory, Kawasaki Disease Research Center, NHC Key Laboratory of Medical Embryogenesis and Developmental Molecular Biology, Shanghai Key Laboratory of Embryo and Reproduction Engineering, Shanghai, China.
Shun Chen *Department of Cardiology, Shanghai Children's Hospital, School of Medicine, Shanghai Jiao Tong University, Pediatric Allergy and Immune Disease Laboratory, Kawasaki Disease Research Center, NHC Key Laboratory of Medical Embryogenesis and Developmental Molecular Biology, Shanghai Key Laboratory of Embryo and Reproduction Engineering, Shanghai, China.
Ge YanDepartment of Cardiology, Shanghai Children's Hospital, School of Medicine, Shanghai Jiao Tong University, Pediatric Allergy and Immune Disease Laboratory, Kawasaki Disease Research Center, NHC Key Laboratory of Medical Embryogenesis and Developmental Molecular Biology, Shanghai Key Laboratory of Embryo and Reproduction Engineering, Shanghai, China.
Junmin ZhengDepartment of Cardiology, Shanghai Children's Hospital, School of Medicine, Shanghai Jiao Tong University, Pediatric Allergy and Immune Disease Laboratory, Kawasaki Disease Research Center, NHC Key Laboratory of Medical Embryogenesis and Developmental Molecular Biology, Shanghai Key Laboratory of Embryo and Reproduction Engineering, Shanghai, China.
Qingzhu QiuDepartment of Cardiology, Shanghai Children's Hospital, School of Medicine, Shanghai Jiao Tong University, Pediatric Allergy and Immune Disease Laboratory, Kawasaki Disease Research Center, NHC Key Laboratory of Medical Embryogenesis and Developmental Molecular Biology, Shanghai Key Laboratory of Embryo and Reproduction Engineering, Shanghai, China.
Shujia LinDepartment of Cardiology, Shanghai Children's Hospital, School of Medicine, Shanghai Jiao Tong University, Pediatric Allergy and Immune Disease Laboratory, Kawasaki Disease Research Center, NHC Key Laboratory of Medical Embryogenesis and Developmental Molecular Biology, Shanghai Key Laboratory of Embryo and Reproduction Engineering, Shanghai, China.
Yanfang ZongDepartment of Cardiology, Shanghai Children's Hospital, School of Medicine, Shanghai Jiao Tong University, Pediatric Allergy and Immune Disease Laboratory, Kawasaki Disease Research Center, NHC Key Laboratory of Medical Embryogenesis and Developmental Molecular Biology, Shanghai Key Laboratory of Embryo and Reproduction Engineering, Shanghai, China.
Haishuang ChangShanghai Institute Precision Medicine, Ninth People's Hospital, School of Medicine, Shanghai Jiao Tong University Shanghai, Shanghai, China.
Alex Chia Yu ChangShanghai Institute Precision Medicine, Ninth People's Hospital, School of Medicine, Shanghai Jiao Tong University Shanghai, Shanghai, China.
Ying WuDepartment of Pathology, Shanghai Children's Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China.
Cuilan HouDepartment of Cardiology, Shanghai Children's Hospital, School of Medicine, Shanghai Jiao Tong University, Pediatric Allergy and Immune Disease Laboratory, Kawasaki Disease Research Center, NHC Key Laboratory of Medical Embryogenesis and Developmental Molecular Biology, Shanghai Key Laboratory of Embryo and Reproduction Engineering, Shanghai, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cystathionine γ-lyase (CSE) is a major enzyme that produces hydrogen sulfide (H

Indexed as

accelerated agingcystathionine γ-lyasehydrogen sulfidemitochondriaPI3K-AKT pathway

Identifiers

PMID39108752
PMCPMC11300353

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.