Evidence map›Paper›PMID 39108647›Full record

ArticleIranian journal of pharmaceutical research : IJPR

Untargeted LC/HRMS Metabolomics Analysis and Anticancer Activity Assay on MCF-7 and A549 Cells from

Kasta Gurning, Suratno Suratno, Endang Astuti, Winarto Haryadi

Abstract read
In one paragraph

Article in Iranian journal of pharmaceutical research : IJPR. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Kasta GurningDepartment of Chemistry, Faculty of Mathematics and Natural Sciences, Universitas Gadjah Mada, 55281, Yogyakarta, Indonesia.ORCID https://orcid.org/0000-0002-0676-0030
Suratno SuratnoDepartment of Chemistry, Faculty of Mathematics and Natural Sciences, Universitas Gadjah Mada, 55281, Yogyakarta, Indonesia.ORCID https://orcid.org/0000-0002-1033-8844
Endang AstutiDepartment of Chemistry, Faculty of Mathematics and Natural Sciences, Universitas Gadjah Mada, 55281, Yogyakarta, Indonesia.ORCID https://orcid.org/0000-0002-6401-2719
Winarto HaryadiDepartment of Chemistry, Faculty of Mathematics and Natural Sciences, Universitas Gadjah Mada, 55281, Yogyakarta, Indonesia.ORCID https://orcid.org/0000-0001-7970-1528

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Cancer remains the leading cause of death globally, with breast cancer being the foremost cause among women and lung cancer ranking second for both women and men. Objectives: This study aimed to identify the metabolomic content of Methods: The research methodology involved maceration using ethanol, followed by multistage partitioning with solvents n-hexane, chloroform, and ethyl acetate. Phytochemical screening was performed using standard reagents to detect the presence of alkaloids, phenolics, polyphenols, flavonoids, steroids/triterpenoids, and saponins. Metabolomic profiling was conducted using LC/HRMS, and the anticancer activities against lung cancer cells (A549) and breast cancer cells (MCF-7) were assessed using the MTT assay. Results: The results showed that the Conclusions: The diverse metabolomic profile of the

Indexed as

A549 CellsColeus amboinicusLC/HRMSMCF-7 CellsMetabolomics

Identifiers

PMID39108647
PMCPMC11302430

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.