Evidence map›Paper›PMID 39108520›Full record

ArticlemedRxiv : the preprint server for health sciences2024

High-sensitivity detection of

Alaina M Olson, Rachel C Wood, Kris M Weigel, Alexander J Yan, Katherine A Lochner, Rane B Dragovich, Angelique K Luabeya, Paul Yager, Mark Hatherill, Gerard A Cangelosi

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in medRxiv : the preprint server for health sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors.

Alaina M OlsonDepartment of Environmental and Occupational Health Sciences, University of Washington, Seattle, Washington, United States of America.ORCID 0000-0003-2384-5025
Rachel C WoodDepartment of Environmental and Occupational Health Sciences, University of Washington, Seattle, Washington, United States of America.
Kris M WeigelDepartment of Environmental and Occupational Health Sciences, University of Washington, Seattle, Washington, United States of America.
Alexander J YanDepartment of Bioengineering, University of Washington, Seattle, Washington, United States of America.ORCID 0009-0005-4279-1036
Katherine A LochnerDepartment of Environmental and Occupational Health Sciences, University of Washington, Seattle, Washington, United States of America.
Rane B DragovichDepartment of Environmental and Occupational Health Sciences, University of Washington, Seattle, Washington, United States of America.
Angelique K LuabeyaSouth African Tuberculosis Vaccine Initiative, Institute of Infectious Disease & Molecular Medicine and Department of Pathology, Faculty of Health Sciences, University of Cape Town, South Africa.ORCID 0000-0003-2008-0450
Paul YagerDepartment of Bioengineering, University of Washington, Seattle, Washington, United States of America.ORCID 0000-0003-1271-4599
Mark HatherillSouth African Tuberculosis Vaccine Initiative, Institute of Infectious Disease & Molecular Medicine and Department of Pathology, Faculty of Health Sciences, University of Cape Town, South Africa.
Gerard A CangelosiDepartment of Environmental and Occupational Health Sciences, University of Washington, Seattle, Washington, United States of America.ORCID 0000-0003-0006-6520

Funding

The Center for Innovation in Point-of-Care Technologies for HIV/AIDS atNorthwestern University (C-THAN) Supplemental RequestU54EB027049 · NIBIB · NORTHWESTERN UNIVERSITY · PI Kara M Palamountain · 2018 to 2026
$24.0M
Non-invasive diagnosis of adult pulmonary tuberculosisR01AI139254 · NIAID · UNIVERSITY OF WASHINGTON · PI CANGELOSI, GERARD A · 2019 to 2022
$1.3M
High-sensitivity tongue swab testing for tuberculosisR21AI185407 · NIAID · UNIVERSITY OF WASHINGTON · PI CANGELOSI, GERARD A · 2024 to 2025
$428k
NIAID NIH HHS R01 AI139254NIAID NIH HHS R21 AI185407NIBIB NIH HHS U54 EB027049
6 · The paper itself

Abstract

Tongue swab (TS) sampling combined with qPCR to detect Importance: Improved testing for tuberculosis (TB) is needed. Using a more accessible sample type than sputum may enable the detection of more cases, but it is critical that alternative samples be tested appropriately. Here, we describe two new, highly accurate methods for testing tongue swabs for TB DNA.

Identifiers

PMID39108520
PMCPMC11302704

What OpenQuestion holds

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LicenceCC BY-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.