Evidence map›Paper›PMID 39108119›Full record

ReviewAnti-inflammatory & anti-allergy agents in medicinal chemistry2024

Ferulic Acid: A Review of Mechanisms of Action, Absorption, Toxicology, Application on Wound Healing.

Ana Flávia Lawall Werneck Cerqueira, Humberto de Mello Brandão, Guilherme Diniz Tavares, Mirian Pereira Rodarte

Abstract readReview
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In one paragraph

Review in Anti-inflammatory & anti-allergy agents in medicinal chemistry, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Ana Flávia Lawall Werneck CerqueiraDepartment of Pharmaceutical Sciences, Faculty of Pharmacy, Federal University of Juiz de Fora, Juiz de Fora, Brasil.
Humberto de Mello BrandãoEmpresa Brasileira de Pesquisa Agropecuária , EMBRAPA, Juiz de Fora, Brasil.
Guilherme Diniz TavaresDepartment of Pharmaceutical Sciences, Faculty of Pharmacy, Federal University of Juiz de Fora, Juiz de Fora, Brasil.
Mirian Pereira RodarteDepartment of Pharmaceutical Sciences, Faculty of Pharmacy, Federal University of Juiz de Fora, Juiz de Fora, Brasil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ferulic acid is a widely distributed phenolic substance with diverse bioactive properties, which has been widely used in the pharmaceutical, food, and cosmetic industries. Wounds are complex skin lesions to treat and their treatment is long and costly. This encourages the search for alternative treatments, especially in the area of bioactive substances of natural origin.

aimsThis work aims to make a bibliographic survey on studies of the use of ferulic acid in the treatment of wounds.

resultsThe studies found show that ferulic acid acts through different mechanisms of action such as antioxidant, anti-inflammatory, antimicrobial, collagen production, angiogenic, and reepithelialization effects. These properties act synergistically in different stages of healing, which differentiates it from conventional treatments. In addition, ferulic acid has dermal absorption, low skin metabolism, and low toxicity.

conclusionStudies in this area are recent and further research is needed to expand the possibilities and therapeutic efficiency of ferulic acid in wound healing.

Indexed as

AntioxidantsCoumaric AcidsWound HealingAnimalsAnti-Infective AgentsAnti-Inflammatory AgentsHumansSkinSkin AbsorptionAnti-Infective AgentsAnti-Inflammatory AgentsAntioxidantsCoumaric Acidsferulic acidanti-inflammatoryantimicrobialantioxidantferulic acid.natural productsPhenolic

Identifiers

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.