ReviewCurrent topics in medicinal chemistry2025
Eco-friendly Approaches to Chromene Derivatives: A Comprehensive Review of Green Synthesis Strategies.
Review in Current topics in medicinal chemistry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
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Who cites it
4 citing papers in PubMed.
- Synthesis and crystal structure of 2-amino-4-(3-isobutyl-1-phenyl-1Acta crystallographica. Section E, Crystallographic communications · 2026Article
- Regioselective green synthesis of some novel indole-substituted 1RSC advances · 2026Article
- Visible-Light Photocatalysis for Sustainable Chromene Synthesis and Functionalization.Chemistry (Weinheim an der Bergstrasse, Germany) · 2025Review
- Halogenated 3-Nitro-2Antibiotics (Basel, Switzerland) · 2025Article
Corrections and comments
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Authors and funding
21 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Synthetic routes of chromene are an area of thrust research due to its wide application as pigments, agrochemicals, cosmetics, and an important nucleus scaffold for various pharmacologically active drugs. The chromene nucleus is an important moiety for the discovery of new drug candidates owing to its broad range of pharmacological actions like antitumor, antiinflammatory, antiviral, and many others. However, traditional synthesis techniques frequently use unsafe reagents and produce hazardous waste, presenting environmental issues. The ecofriendly production of chromene derivatives utilizes sustainable raw materials, non-toxic catalysts, and gentle reaction conditions to reduce ecological consequences. Innovative methods like microwave irradiation, ultrasound synthesis, the use of environmentally friendly solvents, a catalyst- based approach with minimal environmental impact, and mechanochemistry-mediated synthesis are implemented. These approaches provide benefits in scalability, cost-effectiveness, and ease of purification. This review compiles and presents various recently reported green synthetic strategies of chromene and its derivatives and gives the reader a clear idea of the detailed and critical aspects of various synthetic protocols described.
Indexed as
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.