Evidence map›Paper›PMID 39107999›Full record

ArticleRenal failure2024

Unmasking the silent culprit: recurrent exercise-induced acute kidney injury in a Chinese adolescent with renal hypouricemia.

Yuan Gao, Lu Xu, Mingming Wei, Xiaohan Qu, Tongtong Pan, Xinjian Li

Abstract readCase Reports
In one paragraph

Article in Renal failure, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Yuan GaoJining Medical University, Jining, Shandong, China.ORCID 0009-0004-9399-6712
Lu XuDepartment of Hemopurification, Affiliated Hospital of Jining Medical College, Jining, Shandong, China.
Mingming WeiDepartment of Nephrology, Affiliated Hospital of Jining Medical College, Jining, Shandong, China.
Xiaohan QuDepartment of Nephrology, Affiliated Hospital of Jining Medical College, Jining, Shandong, China.
Tongtong PanJining Medical University, Jining, Shandong, China.
Xinjian LiDepartment of Nephrology, Affiliated Hospital of Jining Medical College, Jining, Shandong, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Primary renal hypouricemia (RHUC) is a rare autosomal recessive disorder with a mean duration of end-stage acute kidney injury (EIAKI) of 14 days. The pathogenesis of EIAKI in patients with RHUC remains unclear. Several hypotheses have been proposed, including those related to the renal vasoconvulsive effect and the elevating effect of xanthine oxidase (XO). The effect of xanthine oxidase (XO) is most often observed following strenuous anaerobic exercise, which is frequently accompanied by low back pain, nausea, and acute kidney injury (AKI). Consequently, we postulate that EIAKI could be prevented by avoiding strenuous exercise, thus preventing the onset and recurrence of EIAKI. In this paper, we present a case of recurrent EIAKI in a patient with RHUC and a mutation in the SLC2A9 gene.

Indexed as

Acute Kidney InjuryExerciseRenal Tubular Transport, Inborn ErrorsAdolescentChinaEast Asian PeopleGlucose Transport Proteins, FacilitativeHumansMaleMutationRecurrenceUrinary CalculiXanthine OxidaseGlucose Transport Proteins, FacilitativeSLC2A9 protein, humanXanthine Oxidaseautosomal recessive disorderbiopsyEIAKIKidneyRHUCSLC2A9 gene

Identifiers

PMID39107999
PMCPMC11308975

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.