ArticleCNS neuroscience & therapeutics2024
Safety and efficiency of deep brain stimulation in the elderly patients with Parkinson's disease.
Article in CNS neuroscience & therapeutics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
6 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Robotic systems in cranial surgery: a systematic review of accuracy, clinical outcomes, and adverse events.Neurosurgical review · 2026Pooled it
- Gradient boosting machine model predicts psychiatric complications after deep brain stimulation in Parkinson's disease.World journal of psychiatry · 2026Article
- Deep brain stimulation surgical timing, outcomes, and prognostic factors in patients with Parkinson's disease: A Chinese retrospective multicenter cohort study.PLoS medicine · 2025Article
- Deep Brain Stimulation in Parkinson's Disease Patients Over 75 Years of Age: A Single-Institution Retrospective Analysis.CNS neuroscience & therapeutics · 2025Article
- The combination ofQuantitative imaging in medicine and surgery · 2024Article
- Safety and efficiency of deep brain stimulation in the elderly patients with Parkinson's disease.CNS neuroscience & therapeutics · 2024Article
Corrections and comments
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Authors and funding
13 authors.
Funding
Abstract
aimsDeep brain stimulation (DBS) is not routinely performed in elderly patients (≥75 years old) to date because of concerns about complications and decreased benefit. This study aimed to evaluate the safety and efficacy of DBS in elderly patients with Parkinson's disease.
methodsA retrospective analysis was performed using data from 40 elderly patients from four centers who were treated with neurosurgical robot-assisted DBS between September 2016 and December 2021. These patients were followed up for a minimum period of 2 years, with a subgroup of nine patients followed up for 5-7 years. Patient demographic characteristics, surgical information, pre- and postoperative motor scores, non-motor scores, activities of daily living, and complications were retrospectively analyzed.
resultsThe mean surgical procedure duration was 1.65 ± 0.24 h, with a mean electrode implantation duration of 1.10 ± 0.23 h and a mean pulse generator implantation duration of 0.55 ± 0.07 h. The mean pneumocephalus volume, electrode fusion error, and Tao's DBS surgery scale were 16.23 ± 12.81 cm
conclusionRobot-assisted DBS surgery for the elderly patients with Parkinson's disease is accurate and safe. Motor symptoms and ADL significantly improve and patients can benefit from long-term neuromodulation, which may decrease the risk of death.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.