Evidence map›Paper›PMID 39107585›Full record

ArticleInternational microbiology : the official journal of the Spanish Society for Microbiology2025

Characterization of susceptibility patterns and adaptability of the newly emerged Candida auris.

Matlou D Semenya, Adebowale E Aladejana, Sizwe I Ndlovu

Abstract read
In one paragraph

Article in International microbiology : the official journal of the Spanish Society for Microbiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Pharmacological advances inJournal of enzyme inhibition and medicinal chemistry · 2026
    Review
  2. Review
  3. Review
  4. Microbiology spectrum · 2026
    Article
  5. We Are Family: Comparative Study ofPathogens (Basel, Switzerland) · 2026
    Article
  6. Article
  7. First Report ofJournal of fungi (Basel, Switzerland) · 2025
    Article
  8. Article
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Matlou D SemenyaDepartment of Biotechnology and Food Technology, Faculty of Science, University of Johannesburg, Johannesburg, 2028, South Africa.
Adebowale E AladejanaDepartment of Biotechnology and Food Technology, Faculty of Science, University of Johannesburg, Johannesburg, 2028, South Africa.
Sizwe I NdlovuDepartment of Biotechnology and Food Technology, Faculty of Science, University of Johannesburg, Johannesburg, 2028, South Africa. msizwe@uj.ac.za.

Funding

National Research Foundation 129778
6 · The paper itself

Abstract

The emergence of Candida auris has caused a major concern in the public health worldwide. This novel fungus is characterized by its multidrug resistance profile, ability to thrive in harsh and stressful conditions, as well as high temperatures and salt concentrations, persistence on hospital surfaces, causing nosocomial infections and outbreaks, and unique fitness properties. Here, we study the antifungal susceptibility patterns, thermotolerance, and halotolerance of 15 putative C. auris clinical isolates from Inkosi Albert Academic Hospital, Durban, South Africa. Five of the C. auris isolates showed resistance to all three antifungals (fluconazole, amphotericin B, and micafungin) and were selected for characterization of their adaptability mechanisms. Four of the tested multidrug-resistant C. auris isolates (C. auris strain F25, C. auris strain F276, C. auris F283, and C. auris M153) showed good growth when exposed to high temperature (42 °C) and salinity (10% NaCl) conditions whereas one isolate (C. auris F65) showed moderate growth under these conditions. Candida parapsilosis showed poor growth whereas C. albicans no growth under these conditions. The five C. auris strains were positive for all the adaptive features.

Indexed as

Adaptation, PhysiologicalAntifungal AgentsCandidaCandida aurisCandidiasisAmphotericin BDrug Resistance, FungalDrug Resistance, Multiple, FungalFluconazoleHumansMicafunginMicrobial Sensitivity TestsSouth AfricaThermotoleranceAmphotericin BAntifungal AgentsFluconazoleMicafunginAdaptive featuresCandida aurisHalotoleranceResistanceThermotoleranceVirulence traits

Identifiers

PMID39107585
PMCPMC11906518

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.