ArticleHigh blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension2024
Hyperuricemia in Cardiac Rehabilitation Patients: Prevalence and Association with Functional Improvement and Left Ventricular Ejection Fraction.
Article in High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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4 citing papers in PubMed.
- Outpatients' cardiac rehabilitation: the long-term experience of the Niguarda Hospital.International journal of cardiology. Cardiovascular risk and prevention · 2026Article
- Are clinical improvements in anxiety or depression associated with improvement in walking fitness following a cardiac rehabilitation programme?Open heart · 2026Observational
- Exercise effects on the link between inflammation, metabolic health and hyperuricemia: a prospective cohort study.Lipids in health and disease · 2025Article
- The prevalence and risk factors of hyperuricemia in patients with Newly-diagnosed coronary artery disease from 2017 to 2021.BMC cardiovascular disorders · 2025Article
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15 authors.
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Abstract
introductionThe role of uric acid (UA) and Hyper Uricemia (HU) in cardiac rehabilitation (CR) patients have been very little studied.
aimTo evaluate the prevalence of HU and if it is associated to the functional improvement obtained or the left ventricular Ejection Fraction (EF) in CR patients after Acute or Chronic Coronary Syndrome (ACS and CCS respectively).
methodsWe enrol 411 patients (62.4 ± 10.2 years; males 79.8%) enrolled in the CR program at Niguarda Hospital (Milan) from January 2012 to May 2023. HU was defined both as the classic cut-off (> 6 for females, > 7 mg/dL for males) and with the newly identified one by the URRAH study (> 5.1 for females, > 5.6 mg/dL for males). All patients performed a 6MWT and an echocardiography at the beginning and at the end of CR program.
resultsMean UA values were within the normal range (5.6 ± 1.4 mg/dL) with 19.5% (classic cut-off) HU patients with an increase to 47.4% with the newer one. Linear regression analysis showed no role for UA in determining functional improvement, while UA and hyperuricemia (classic cut-off) were associated to admission and discharge EF. The same was not with the URRAH cut-off.
conclusionsHU is as frequent in CR patients as in those with ACS and CCS. UA didn't correlate with functional recovery while it is associated with admission and discharge EF as also is for HU (classic cut-off). Whit the URRAH cut-off HU prevalence increases significantly, however, it doesn't show any significant association with EF.
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