Evidence map›Paper›PMID 39107430›Full record

ArticlePediatric cardiology2025

Update of How Pediatric Cardiologists Noninvasively Evaluate Patients with Hypoplastic Left Heart Syndrome: 2013 vs. 2023.

Angela C Onorato, Craig Fleishman, Holly Nadorlik, David Brown, Chance Alvarado, Sara Conroy, Corey Stiver, Clifford L Cua

Abstract read
PubMed Publisher
In one paragraph

Article in Pediatric cardiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Angela C OnoratoHeart Center, Nationwide Children's Hospital, Columbus, OH, 43205, USA. Angela.Onorato@nationwidechildrens.org.
Craig FleishmanHeart Center, Orlando Health Arnold Palmer Hospital for Children, Orlando, FL, USA.
Holly NadorlikDivision of Cardiology & Cardiovascular Medicine, Children's Institute Department of Heart, Vascular, & Thoracic, Cleveland Clinic Children's, Cleveland, OH, USA.
David BrownDepartment of Cardiology, Boston Children's Hospital, Boston, MA, USA.
Chance AlvaradoHeart Center, Nationwide Children's Hospital, Columbus, OH, 43205, USA.
Sara ConroyHeart Center, Nationwide Children's Hospital, Columbus, OH, 43205, USA.
Corey StiverHeart Center, Nationwide Children's Hospital, Columbus, OH, 43205, USA.
Clifford L CuaHeart Center, Nationwide Children's Hospital, Columbus, OH, 43205, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Noninvasive functional assessment of systemic right ventricles (RV) in hypoplastic left heart syndrome (HLHS) is challenging. This study aimed to compare pediatric cardiologists' current noninvasive imaging practices to those reported in 2013. A web-based survey was distributed to pediatric cardiologists via various listservs which queried timing of echocardiograms during HLHS palliative stages and measurements of RV function. Demographics of 156 participants who completed the 2023 survey were similar to survey participants in 2013 (n = 222). Respondents were mostly male (62%), echocardiographers (48%), in university-based practice (67%) in North America (95%). Echocardiograms were predominantly obtained monthly during interstage I (41%), every 6 months during interstage II (56%), and every year post-Fontan (68%), which is consistent from 2013. Routine cardiac magnetic resonance imaging (cMRI) significantly increased in interstage II (8.2%, 17%) and post-Fontan (24%, 56%) populations, respectively. Qualitative assessment (41%), ejection fraction (EF) by 3D (20%), fractional area change (16%), and RV strain/strain rate (13%) were preferred methods for systolic assessment, whereas a plurality of respondents (41%) did not believe RV diastolic measurements were valid. The largest gap between currently obtained and desired measurements existed for EF by 3D (46.5% points) and RV strain/strain rate (44.5% points). No differences existed between imagers compared to non-imagers. Variability in evaluating HLHS patients continues among pediatric cardiologists compared to 10 years ago. Qualitative assessment remains the primary RV systolic functional evaluation. Providers do not rely on quantitative RV diastolic function assessments in HLHS patients. Use of cMRI is increasing for RV functional analysis.

Indexed as

CardiologistsEchocardiographyHeart VentriclesHypoplastic Left Heart SyndromePractice Patterns, Physicians'ChildFemaleHumansMagnetic Resonance Imaging, CineMaleSurveys and QuestionnairesCardiac magnetic resonance imagingEchocardiogramHypoplastic left heart syndromeSurvey

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.