ArticleNature communications2024
Variation in a Poaceae-conserved fatty acid metabolic gene cluster controls rice yield by regulating male fertility.
Article in Nature communications, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
11 citing papers in PubMed.
- Sweet Potato Gene Clusters Control Anthocyanin Biosynthesis and Leaf Morphology.Plant biotechnology journal · 2026Article
- Integrated multi-omics analysis reveals a lipid-redox regulatory network underlying drought tolerance and yield stability in rice.BMC plant biology · 2026Article
- The ATP-Citrate Lyase Subunit ACLA, Coordinates Rice Pollen Development by Coupling Transcriptional Regulation with Metabolic Homeostasis.Rice (New York, N.Y.) · 2026Article
- Rice roots recruit Bacillus via the secretion of heptadecanoic acid.Nature plants · 2026Article
- Genetic Determinants and Breeding Strategies for Rice Cooking and Eating Quality: A Comprehensive Review.Plant biotechnology journal · 2026Review
- Integrating Metabolomics and Proteomics to Reveal the Regulatory Network Governing the Natural Variation in Rice Seed Germination Rate.Plants (Basel, Switzerland) · 2026Article
- Alternative polyadenylation and metabolic profiling in young panicle development of hybrid rice and its parents.Rice (New York, N.Y.) · 2025Article
- Article
- Molecular Basis of Lipid Metabolism inPlants (Basel, Switzerland) · 2024Review
- Compositional Analysis of Grape Berries: Mapping the Global Metabolism of Grapes.Foods (Basel, Switzerland) · 2024Article
- Unraveling the specialized metabolic pathways in medicinal plant genomes: a review.Frontiers in plant science · 2024Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
14 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A wide variety of metabolic gene clusters exist in eukaryotic genomes, but fatty acid metabolic gene clusters have not been discovered. Here, combining with metabolic and phenotypic genome-wide association studies, we identify a major locus containing a six-gene fatty acid metabolic gene cluster on chromosome 3 (FGC3) that controls the cutin monomer hydroxymonoacylglycerols (HMGs) contents and rice yield, possibly through variation in the transcription of FGC3 members. We show that HMGs are sequentially synthesized in the endoplasmic reticulum by OsFAR2, OsKCS11, OsGPAT6, OsCYP704B2 and subsequently transported to the apoplast by OsABCG22 and OsLTPL82. Mutation of FGC3 members reduces HMGs, leading to defective male reproductive development and a significant decrease in yield. OsMADS6 and OsMADS17 directly regulate FGC3 and thus influence male reproduction and yield. FGC3 is conserved in Poaceae and likely formed prior to the divergence of Pharus latifolius. The eukaryotic fatty acid and plant primary metabolic gene cluster we identified show a significant impact on the origin and evolution of Poaceae and has potential for application in hybrid crop breeding.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.