ArticleNature communications2024
Loss of cold tolerance is conferred by absence of the WRKY34 promoter fragment during tomato evolution.
Article in Nature communications, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 28 papers.
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Who cites it
28 citing papers in PubMed.
- A peach esterase/lipase mediates lipid remodeling as a protective mechanism against chilling injury.Plant physiology · 2026Article
- A cooperative regulatory module between TAGL2 and JMJC1 activates specific defense genes against root-knot nematodes in tomato.The New phytologist · 2026Article
- Dual Repression by IPA1 Fine-Tunes OsbZIP79-Mediated Salt Tolerance in Rice.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Fine mapping and candidate genes analysis for flesh thickness major locusHorticulture research · 2026Article
- Genome-Wide Analysis of theInternational journal of molecular sciences · 2026Article
- Single-Cell CRISPR: An Efficient Strategy for Decoding Plant Cis-Regulatory Complexity.Plant biotechnology journal · 2026Review
- Integrative analysis of transcriptome and chromatin accessibility reveals promoter-proximal regulation and identifies candidate ABC transporters associated with cold stress responses in maize.BMC plant biology · 2026Article
- Molecular mechanism of cold acclimation regulating freezing tolerance in Prunus mume.Plant physiology · 2026Article
- SlMYB17 Antagonises the SlCBF Pathway to Negatively Regulate Tomato Chilling Tolerance.Plant biotechnology journal · 2026Article
- WRKY27-RAP2.7 Regulatory Module Promotes Cold Tolerance via Modulation of Lignin Biosynthesis and Redox Homeostasis by Regulating Cinnamyl Alcohol Dehydrogenase 7 and Glutathione S-Transferase F6.Plant biotechnology journal · 2026Article
- Cloning ofGenes · 2026Article
- New insights into controlling horticultural crop quality deterioration caused by cold stress: epigenetic modification.Horticulture research · 2026Article
- A tomato telomere-to-telomere super-pangenome empowers stress resilience breeding.Nature genetics · 2026Article
- Transcriptome-based identification of the WRKY gene family in Polygala tenuifolia Willd. and their response to cold stress.BMC plant biology · 2026Article
- CmHY5-CmWRKY23/69-Horticulture research · 2026Article
- Chromatin accessibility dynamics and a hierarchical transcriptional regulatory network for shoot apex cold stress inForestry research · 2026Article
- Long Non-Coding RNAs in the Cold-Stress Response of Horticultural Plants: Molecular Mechanisms and Potential Applications.International journal of molecular sciences · 2025Review
- Genome-Wide Identification of the AP2/ERF Gene Family and Functional Analysis ofPlants (Basel, Switzerland) · 2025Article
- WRKYs as regulatory hubs of secondary metabolic networks: Diverse inducers and distinct responses.Plant communications · 2025Review
- Growth-Promoting Effects of Dark Septate Endophytes FungusJournal of fungi (Basel, Switzerland) · 2025Article
Corrections and comments
- Erratum issued
Authors and funding
9 authors.
Funding
Abstract
Natural evolution has resulted in reduced cold tolerance in cultivated tomato (Solanum lycopersicum). Herein, we perform a combined analysis of ATAC-Seq and RNA-Seq in cold-sensitive cultivated tomato and cold-tolerant wild tomato (S. habrochaites). We identify that WRKY34 has the most significant association with differential chromatin accessibility and expression patterns under cold stress. We find that a 60 bp InDel in the WRKY34 promoter causes differences in its transcription and cold tolerance among 376 tomato accessions. This 60 bp fragment contains a GATA cis-regulatory element that binds to SWIBs and GATA29, which synergistically suppress WRKY34 expression under cold stress. Moreover, WRKY34 interferes with the CBF cold response pathway through regulating transcription and protein levels. Our findings emphasize the importance of polymorphisms in cis-regulatory regions and their effects on chromatin structure and gene expression during crop evolution.
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