Evidence map›Paper›PMID 39106042›Full record

ArticleBiochemistry2024

Extracellular Domain of IL-10 Receptor Chain-2 (IL-10R2) and Its Arginine-Containing Peptides Are Susceptible Substrates for Human Prostate Kallikrein-2 (KLK2).

Juliana R Oliveira, José Thalles Lacerda, Tarciso A Sellani, Elaine G Rodrigues, Luiz R Travassos, Maria A Juliano, Luiz Juliano

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biochemistry, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Juliana R OliveiraDepartment of Biophysics, Escola Paulista de Medicina, Federal University of São Paulo, Rua Três de Maio 100, São Paulo 04044-20, Brazil.
José Thalles LacerdaDepartment of Biophysics, Escola Paulista de Medicina, Federal University of São Paulo, Rua Três de Maio 100, São Paulo 04044-20, Brazil.
Tarciso A SellaniDepartment of Microbiology, Immunology and Parasitology, Escola Paulista de Medicina, Federal University of São Paulo, Rua Botucatu 862, São Paulo 04023-901, Brazil.
Elaine G RodriguesDepartment of Microbiology, Immunology and Parasitology, Escola Paulista de Medicina, Federal University of São Paulo, Rua Botucatu 862, São Paulo 04023-901, Brazil.
Luiz R TravassosDepartment of Microbiology, Immunology and Parasitology, Escola Paulista de Medicina, Federal University of São Paulo, Rua Botucatu 862, São Paulo 04023-901, Brazil.
Maria A JulianoDepartment of Biophysics, Escola Paulista de Medicina, Federal University of São Paulo, Rua Três de Maio 100, São Paulo 04044-20, Brazil.
Luiz JulianoDepartment of Biophysics, Escola Paulista de Medicina, Federal University of São Paulo, Rua Três de Maio 100, São Paulo 04044-20, Brazil.ORCID 0000-0002-5589-2822

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The kallikrein-related peptidase KLK2 has restricted expression in the prostate luminal epithelium, and its protein target is unknown. The present work reports the hydrolytic activities of KLK2 on libraries of fluorescence resonance energy-transfer peptides from which the sequence SYRIF was the most susceptible substrate for KLK2. The sequence SYRIF is present at the extracellular

Indexed as

KallikreinsAnimalsArginineHumansInterleukin-10MacrophagesMaleMicePeptidesProstateProtein DomainsSubstrate SpecificityArginineInterleukin-10KallikreinsKLK2 protein, humanPeptides

Identifiers

PMID39106042
PMCPMC11339918

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.