Evidence map›Paper›PMID 39105944›Full record

SynthesisJournal of robotic surgery2024

Perioperative, functional and oncologic outcomes of percutaneous ablation versus minimally invasive partial nephrectomy for clinical T1 renal tumors: outcomes from a pooled analysis.

Kun-Peng Li, Shun Wan, Si-Yu Chen, Chen-Yang Wang, Shan-Hui Liu, Li Yang

Abstract readComparative StudyMeta-AnalysisSystematic Review
PubMed Publisher
In one paragraph

Synthesis in Journal of robotic surgery, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Kun-Peng Li *Department of Urology, The Second Hospital of Lanzhou University, Lanzhou, China.
Shun Wan *Department of Urology, The Second Hospital of Lanzhou University, Lanzhou, China.
Si-Yu Chen *Department of Urology, The Second Hospital of Lanzhou University, Lanzhou, China.
Chen-Yang WangDepartment of Urology, The Second Hospital of Lanzhou University, Lanzhou, China.
Shan-Hui LiuDepartment of Urology, The Second Hospital of Lanzhou University, Lanzhou, China. liushh2014@lzu.edu.cn.
Li YangDepartment of Urology, The Second Hospital of Lanzhou University, Lanzhou, China. ery_yangli@lzu.edu.cn.

Funding

Exploring the Accuracy and Mechanisms of Non-Invasive Urinary HTRA1 Molecular Detection in Bladder Cancer Diagnosis Grant numbers 23JRRA1006Investigation of the Effects and Mechanisms of HTRA1 on Bladder Tumors Through Combined Non-invasive Urinary Metabolomics Grant numbers 22YF7FA090Multimodal Urinary Analysis for the Identification of Bladder Tumor Biomarkers and Investigation into the Molecular Mechanisms of HTRA1 Grant numbers 2023-4-34the Cuiying Scientifc and Technological Innovation Program of Lanzhou University Second Hospital Grant numbers CY2022-MS-A09Traditional Chinese Medicine Scientific Research Project of Gansu Province, China GZKP-2023-36
6 · The paper itself

Abstract

The objective of this study was to perform a comprehensive pooled analysis aimed at comparing the efficacy and safety of percutaneous ablation (PCA) versus minimally invasive partial nephrectomy (MIPN), including robotic and laparoscopic approaches, in patients diagnosed with cT1 renal tumors. We conducted a comprehensive search across four major electronic databases: PubMed, Embase, Web of Science, and the Cochrane Library, targeting studies published in English up to April 2024. The primary outcomes evaluated in this analysis included perioperative outcomes, functional outcomes, and oncological outcomes. A total of 2449 patients across 17 studies were included in the analysis. PCA demonstrated superior outcomes compared to MIPN in terms of shorter hospital stays (WMD: - 2.13 days; 95% Confidence Interval [CI]: - 3.29, - 0.97; p = 0.0003), reduced operative times (WMD: - 109.99 min; 95% CI: - 141.40, - 78.59; p < 0.00001), and lower overall complication rates (OR: 0.54; 95% CI: 0.40, 0.74; p = 0.0001). However, PCA was associated with a higher rate of local recurrence when compared to MIPN (OR: 3.81; 95% CI: 2.45, 5.92; p < 0.00001). Additionally, no significant differences were observed in major complications, estimated glomerular filtration rate decline, creatinine variation, overall survival, recurrence-free survival, and disease-free survival between the two treatment modalities. PCA presents a notable disadvantage regarding local recurrence rates in comparison to MIPN. However, PCA offers several advantages over MIPN, including shorter durations of hospital stay, reduced operative times, and lower complication rates, while achieving similar outcomes in other oncologic metrics.

Indexed as

Kidney NeoplasmsMinimally Invasive Surgical ProceduresNephrectomyPostoperative ComplicationsHumansLaparoscopyLength of StayNeoplasm Recurrence, LocalNeoplasm StagingOperative TimeRobotic Surgical ProceduresTreatment OutcomeClinical T1Meta-analysisMinimally invasive partial nephrectomyPercutaneous ablationRenal tumors

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.