Evidence map›Paper›PMID 39105934›Full record

Trial reportAging clinical and experimental research2024

A transitional care program in a technologically monitored in-hospital facility reduces the length of hospital stay and improves multidimensional frailty in older patients: a Randomized Clinical Trial.

Alberto Pilotto, Wanda Morganti, Marina Barbagelata, Emanuele Seminerio, Simona Morelli, Romina Custureri, Simone Dini, Barbara Senesi, Camilla Prete, Gianluca Puleo and 5 more

Registry-linked trialAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Aging clinical and experimental research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06227923 (Development and Validation of a Protected Discharge Model Using Technology in Multimorbidity and Poly-treated Older Subjects. The PRO-HOME Study), which is not on this map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06227923 nacompletednot on this map

Development and Validation of a Protected Discharge Model Using Technology in Multimorbidity and Poly-treated Older Subjects. The PRO-HOME Study

TypeinterventionalSponsorAlberto PilottoRan2021 to 2023Enrolled60ConditionsMultimorbid and Poly-treated Older PeopleArmsPRO-HOME intervention
3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. The sound of longevity: music and technology for healthy ageing.Aging clinical and experimental research · 2026
    Review
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Alberto PilottoDepartment of Geriatric Care, Neurology and Rehabilitation, E.O. Galliera Hospital, Mura delle Cappuccine 14, 16128, Genoa, Italy.
Wanda MorgantiDepartment of Geriatric Care, Neurology and Rehabilitation, E.O. Galliera Hospital, Mura delle Cappuccine 14, 16128, Genoa, Italy. wanda.morganti@galliera.it.
Marina BarbagelataDepartment of Geriatric Care, Neurology and Rehabilitation, E.O. Galliera Hospital, Mura delle Cappuccine 14, 16128, Genoa, Italy.
Emanuele SeminerioDepartment of Geriatric Care, Neurology and Rehabilitation, E.O. Galliera Hospital, Mura delle Cappuccine 14, 16128, Genoa, Italy.
Simona MorelliDepartment of Geriatric Care, Neurology and Rehabilitation, E.O. Galliera Hospital, Mura delle Cappuccine 14, 16128, Genoa, Italy.
Romina CustureriDepartment of Geriatric Care, Neurology and Rehabilitation, E.O. Galliera Hospital, Mura delle Cappuccine 14, 16128, Genoa, Italy.
Simone DiniDepartment of Geriatric Care, Neurology and Rehabilitation, E.O. Galliera Hospital, Mura delle Cappuccine 14, 16128, Genoa, Italy.
Barbara SenesiDepartment of Geriatric Care, Neurology and Rehabilitation, E.O. Galliera Hospital, Mura delle Cappuccine 14, 16128, Genoa, Italy.
Camilla PreteDepartment of Geriatric Care, Neurology and Rehabilitation, E.O. Galliera Hospital, Mura delle Cappuccine 14, 16128, Genoa, Italy.
Gianluca PuleoDepartment of Geriatric Care, Neurology and Rehabilitation, E.O. Galliera Hospital, Mura delle Cappuccine 14, 16128, Genoa, Italy.
Carlo Berutti BergottoInformatic and Technology Unit, E.O. Galliera Hospital, Genoa, Italy.
Francesco ValloneDepartment of Geriatric Care, Neurology and Rehabilitation, E.O. Galliera Hospital, Mura delle Cappuccine 14, 16128, Genoa, Italy.
Carlo CustoderoDepartment of Interdisciplinary Medicine, University of Bari "Aldo Moro", Bari, Italy.
Antonio CamurriCasa Paganini-InfoMus Research Center, Department of Informatics, Bioengineering, Robotics and Systems' Engineering (DIBRIS), , University of Genova, Genoa, Italy.
PRO‐HOME Project Investigators Group

Funding

Ministero della Salute NET-2016-02361805Regione Liguria NET-2016-02361805
6 · The paper itself

Abstract

backgroundLonger length of hospital stay (LOS) negatively affects the organizational efficiency of public health systems and both clinical and functional aspects of older patients. Data on the effects of transitional care programs based on multicomponent interventions to reduce LOS of older patients are scarce and controversial.

aimsThe PRO-HOME study aimed to assess the efficacy in reducing LOS of a transitional care program involving a multicomponent intervention inside a technologically monitored in-hospital discharge facility.

methodsThis is a Randomized Clinical Trial on 60 patients (≥65 years), deemed stable and dischargeable from the Acute Geriatrics Unit, equally assigned to the Control Group (CG) or Intervention Group (IG). The latter underwent a multicomponent intervention including lifestyle educational program, cognitive and physical training. At baseline, multidimensional frailty according to the Multidimensional Prognostic Index (MPI), and Health-Related Quality of Life (HRQOL) were assessed in both groups, along with physical capacities for the IG. Enrolled subjects were evaluated after 6 months of follow-up to assess multidimensional frailty, HRQOL, and re-hospitalization, institutionalization, and death rates.

resultsThe IG showed a significant 2-day reduction in LOS (median days IG = 2 (2-3) vs. CG = 4 (3-6); p < 0.001) and an improvement in multidimensional frailty at 6 months compared to CG (median score IG = 0.25(0.25-0.36) vs. CG = 0.38(0.31-0.45); p = 0.040). No differences were found between the two groups in HRQOL, and re-hospitalization, institutionalization, and death rates. DISCUSSION: Multidimensional frailty is a reversible condition that can be improved by reduced LOS.

conclusionsThe PRO-HOME transitional care program reduces LOS and multidimensional frailty in hospitalized older patients.

trial registrationClinicalTrials.gov n. NCT06227923 (retrospectively registered on 29/01/2024).

Indexed as

Frail ElderlyFrailtyLength of StayTransitional CareAgedAged, 80 and overFemaleGeriatric AssessmentHospitalizationHumansMalePatient DischargeQuality of LifeComprehensive Geriatric AssessmentMultidimensional frailtyMultidimensional Prognostic IndexTransitional care program

Identifiers

PMID39105934
PMCPMC11303417

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.