Evidence map›Paper›PMID 39105830›Full record

Observational studyLangenbeck's archives of surgery2024

Outcomes of patients admitted with malignant small bowel obstruction: a subgroup multicentre observational cohort analysis.

N B Hupfeld, J Burcharth, T K Jensen, I Lolle, L B J Nielsen, M A Tolver, A P Skovsen, H G Smith

Abstract readMulticenter StudyObservational Study
In one paragraph

Observational study in Langenbeck's archives of surgery, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

N B HupfeldDepartment of Surgery, Copenhagen University Hospital-North Zealand, Hilleroed, Denmark. nanna.baekvang.hupfeld@regionh.dk.ORCID https://orcid.org/0009-0007-6594-9769
J BurcharthDepartment of Gastrointestinal and Hepatic Diseases, Copenhagen University Hospital-Herlev and Gentofte, Herlev, Denmark.
T K JensenDepartment of Gastrointestinal and Hepatic Diseases, Copenhagen University Hospital-Herlev and Gentofte, Herlev, Denmark.
I LolleDepartment of Surgery, Copenhagen University Hospital-Amager and Hvidovre, Hvidovre, Denmark.
L B J NielsenDigestive Disease Center, Copenhagen University Hospital-Bispebjerg and Frederiksberg, Copenhagen, Denmark.
M A TolverDepartment of Surgery, Sjaelland University Hospital, Koege, Denmark.
A P SkovsenDepartment of Surgery, Copenhagen University Hospital-North Zealand, Hilleroed, Denmark.
H G SmithDigestive Disease Center, Copenhagen University Hospital-Bispebjerg and Frederiksberg, Copenhagen, Denmark.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introduction and purpose of the studySmall bowel obstruction (SBO) accounts for a substantial proportion of emergency surgical admissions. Malignancy is a common cause of obstruction, either due to a primary tumour or intra-abdominal metastases. However, little is known regarding the current treatment or outcomes of patients with malignant SBO. This study aimed to characterise the treatment of malignant SBO and identify areas for potential improvement and compare overall survival of patients with malignant SBO to patients with non-malignant SBO. MATERIALS AND

methodsThis was a subgroup analysis of a multicentre observational study of patients admitted with SBO. Details regarding these patients' diagnoses, treatments, and outcomes up to 1-year after admission were recorded. The primary outcome was overall survival in patients with malignant SBO.

resultsA total of 316 patients with small bowel obstruction were included, of whom 33 (10.4%) had malignant SBO. Out of the 33 patients with malignant SBO, 20 patients (60.6%) were treated with palliative intent although only 7 patients were seen by a palliative team during admission. Nutritional assessments were performed on 12 patients, and 11 of these patients received parenteral nutrition. 23 patients underwent surgery, with the most common surgical interventions being loop ileostomies (9 patients) and gastrointestinal bypasses (9 patients). 4 patients underwent right hemicolectomies, with a primary anastomosis formed and 1 patient had a right hemicolectomy with a terminal ileostomy. Median survival was 114 days, and no difference was seen in survival between patients treated with or without palliative intent.

conclusionMalignant SBO is associated with significant risks of short-term complications and a poor prognosis. Consideration should be given to the early involvement of senior decision-makers upon patient admission is essential for optimal management and setting expectation for a realistic outcome.

Indexed as

Intestinal ObstructionIntestine, SmallPalliative CareAdultAgedAged, 80 and overCohort StudiesFemaleHumansIntestinal NeoplasmsMaleMiddle AgedSurvival RateTreatment OutcomeMalignant small bowel obstructionOperative vs. non-operative managementOverall survivalPalliative care

Identifiers

PMID39105830
PMCPMC11303426

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.