Evidence map›Paper›PMID 39105754›Full record

ReviewNanomedicine (London, England)2024

Mesoporous silica nanoparticles: a versatile carrier platform in lung cancer management.

Smriti Dhingra, Shuchi Goyal, Divya Thirumal, Preety Sharma, Gurpreet Kaur, Neeraj Mittal

Abstract readReview
In one paragraph

Review in Nanomedicine (London, England), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Review
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  5. Review
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Smriti DhingraChitkara College of Pharmacy, Chitkara University, Punjab, 140401, India.ORCID 0000-0002-1701-5626
Shuchi GoyalChitkara College of Pharmacy, Chitkara University, Punjab, 140401, India.ORCID 0000-0001-9096-3043
Divya ThirumalManipal College of Pharmaceutical Sciences, Manipal Academy of Higher Education, Manipal, 576104,India.ORCID 0000-0002-7927-6821
Preety SharmaChitkara College of Pharmacy, Chitkara University, Punjab, 140401, India.
Gurpreet KaurDepartment of Pharmaceutical Sciences & Drug Research, Punjabi University, Patiala, Punjab, 147002, India.ORCID 0000-0003-4282-3673
Neeraj MittalChitkara College of Pharmacy, Chitkara University, Punjab, 140401, India.ORCID 0000-0002-3334-1712

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mesoporous silica nanoparticles (MSNPs) are inorganic nanoparticles that have been comprehensively investigated and are intended to deliver therapeutic agents. MSNPs have revolutionized the therapy for various conditions, especially cancer and infectious diseases. In this article, the viability of MSNPs' administration for lung cancer therapy has been reviewed. However, certain challenges lay ahead in the successful translation such as toxicology, immunology, large-scale production, and regulatory matters have made it extremely difficult to translate such discoveries from the bench to the bedside. This review highlights recent developments, characteristics, mechanism of action and customization for targeted delivery. This review also covers the most recent data that sheds light on MSNPs' extraordinary therapeutic potential in fighting lung cancer as well as future hurdles.

Indexed as

Lung NeoplasmsNanoparticlesSilicon DioxideAnimalsAntineoplastic AgentsDrug CarriersDrug Delivery SystemsHumansPorosityAntineoplastic AgentsDrug CarriersSilicon Dioxidedrug deliveryinhibitory pathwayslung cancermesoporous silica nanoparticlesmolecular mechanism

Identifiers

PMID39105754
PMCPMC11318747

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.