Evidence map›Paper›PMID 39105753›Full record

ReviewNanomedicine (London, England)2024

Nanomedicine for colon-targeted drug delivery: strategies focusing on inflammatory bowel disease and colon cancer.

Ankaj Kumar, Klaudi K Vaiphei, Naveen Singh, Sri Pada Datta Chigurupati, Shivani Rai Paliwal, Rishi Paliwal, Arvind Gulbake

Abstract readReview
In one paragraph

Review in Nanomedicine (London, England), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Review
  5. Review
  6. Article
  7. Review
  8. Review
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Ankaj KumarDepartment of Pharmaceutics, National Institute of Pharmaceutical Education & Research, Guwahati, Assam, 781101, India.
Klaudi K VaipheiDepartment of Pharmaceutics, National Institute of Pharmaceutical Education & Research, Guwahati, Assam, 781101, India.
Naveen SinghNanomedicine & Bioengineering Research Laboratory, Department of Pharmacy, Indira Gandhi National Tribal University, Amarkantak, Madhya Pradesh, 484887, India.
Sri Pada Datta ChigurupatiDepartment of Pharmaceutics, National Institute of Pharmaceutical Education & Research, Guwahati, Assam, 781101, India.
Shivani Rai PaliwalDepartment of Pharmacy, Guru Ghasidas Vishwavidhyalaya (A Central University), Koni Bilaspur, Chhattisgarh, 495009, India.ORCID 0000-0001-5766-9555
Rishi PaliwalNanomedicine & Bioengineering Research Laboratory, Department of Pharmacy, Indira Gandhi National Tribal University, Amarkantak, Madhya Pradesh, 484887, India.ORCID 0000-0002-7549-707X
Arvind GulbakeDepartment of Pharmaceutics, National Institute of Pharmaceutical Education & Research, Guwahati, Assam, 781101, India.ORCID 0000-0001-7425-8125

Funding

Anusandhan National Research Foundation (SERB) EEQ/2022/000950
6 · The paper itself

Abstract

The nanostructured drug-delivery systems for colon-targeted drug delivery are a promising field of research for localized diseases particularly influencing the colonic region, in other words, ulcerative colitis, Crohn's disease, and colorectal cancer. There are various drug-delivery approaches designed for effective colonic disease treatment, including stimulus-based formulations (enzyme-triggered systems, pH-sensitive systems) and magnetically driven drug-delivery systems. In addition, targeted drug delivery by means of overexpressed receptors also offers site specificity and reduces drug resistance. It also covers GI tract-triggered emulsifying systems, nontoxic plant-derived nanoformulations as advanced drug-delivery techniques as well as nanotechnology-based clinical trials toward colonic diseases. This review gives insight into advancements in colon-targeted drug delivery to meet site specificity or targeted drug-delivery requirements.

Indexed as

ColonColonic NeoplasmsDrug Delivery SystemsInflammatory Bowel DiseasesNanomedicineAnimalsHumanscolon-targeted drug deliverycolorectal cancerCrohn's diseaseinflammatory bowel diseasenanoparticleulcerative colitis

Identifiers

PMID39105753
PMCPMC11318742

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.