Evidence map›Paper›PMID 39105738›Full record

ArticleACS infectious diseases2024

Synthesis of a Phosphoethanolamine Cellulose Mimetic and Evaluation of Its Unanticipated Biofilm Modulating Properties.

C Elizabeth Adams, Sabrina K Spicer, Jennifer A Gaddy, Steven D Townsend

Abstract read
In one paragraph

Article in ACS infectious diseases, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Mechanical Comparison ofACS biomaterials science & engineering · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

C Elizabeth AdamsDepartment of Chemistry, Vanderbilt University, Nashville, Tennessee 37235, United States.
Sabrina K SpicerDepartment of Chemistry, Vanderbilt University, Nashville, Tennessee 37235, United States.ORCID 0009-0008-3960-1221
Jennifer A GaddyDepartment of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee 37232, United States.ORCID 0000-0002-2192-4224
Steven D TownsendDepartment of Chemistry, Vanderbilt University, Nashville, Tennessee 37235, United States.ORCID 0000-0001-5362-7235

Funding

Tumor Immunology and Microenvironment Research ProgramP30CA068485 · NCI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI MATTHEW J TYSKA · 1995 to 2026
$172.8M
Translational Analysis CoreP30DK058404 · NIDDK · VANDERBILT UNIVERSITY MEDICAL CENTER · PI RICHARD M. PEEK · 2002 to 2026
$29.9M
Vanderbilt Diabetes Research CenterP30DK020593 · NIDDK · VANDERBILT UNIVERSITY MEDICAL CENTER · PI OWEN P MCGUINNESS · 2012 to 2026
$29.3M
Shop Module CoreP30EY008126 · NEI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI Kevin L Schey · 1989 to 2026
$19.6M
Vanderbilt Mouse Metabolic Physiology CenterU24DK059637 · NIDDK · VANDERBILT UNIVERSITY · PI WASSERMAN, DAVID H · 2001 to 2015
$14.9M
Bioorganic Approaches Toward Novel Antimicrobial Agents and ChemotherapeuticsR35GM133602 · NIGMS · VANDERBILT UNIVERSITY · PI Steven D. Townsend · 2019 to 2026
$3.0M
Determining the contribution of zinc deficiency to perinatal Group B Streptococcus infectionsR01HD090061 · NICHD · VANDERBILT UNIVERSITY MEDICAL CENTER · PI ARONOFF, DAVID M, GADDY, JENNIFER A · 2017 to 2021
$2.5M
The Role of macrophages in chorioamnionitis and group B streptococcal infectionsR01AI134036 · NIAID · VANDERBILT UNIVERSITY MEDICAL CENTER · PI ARONOFF, DAVID M · 2017 to 2021
$2.4M
Acquisition of a Focused Ion Beam Scanning Electron Microscope with cryo-stageS10OD028704 · OD · VANDERBILT UNIVERSITY · PI TYSKA, MATTHEW J · 2022 to 2022
$1.6M
Toxicant Exposure Impacts Host-pathogen interactions within the Reproductive TractI01BX005352 · VA · VETERANS HEALTH ADMINISTRATION · PI GADDY, JENNIFER A · 2021 to 2024
–
BLRD VA I01 BX005352NCI NIH HHS P30 CA068485NEI NIH HHS P30 EY008126NIAID NIH HHS R01 AI134036NICHD NIH HHS R01 HD090061NIDDK NIH HHS P30 DK020593NIDDK NIH HHS P30 DK058404NIDDK NIH HHS U24 DK059637NIGMS NIH HHS R35 GM133602NIH HHS S10 OD028704
6 · The paper itself

Abstract

When coordinating and adhering to a surface, microorganisms produce a biofilm matrix consisting of extracellular DNA, lipids, proteins, and polysaccharides that are intrinsic to the survival of bacterial communities. Indeed, bacteria produce a variety of structurally diverse polysaccharides that play integral roles in the emergence and maintenance of biofilms by providing structural rigidity, adhesion, and protection from environmental stressors. While the roles that polysaccharides play in biofilm dynamics have been described for several bacterial species, the difficulty in isolating homogeneous material has resulted in few structures being elucidated. Recently, Cegelski and co-workers discovered that uropathogenic

Indexed as

BiofilmsCelluloseEthanolaminesBacterial AdhesionUropathogenic Escherichia coliCelluloseEthanolaminesphosphorylethanolaminebiofilmsEscherichia coliglycopolymersphosphoethanolamine cellulose

Identifiers

PMID39105738
PMCPMC11406534

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.