ArticleRadiology2024
Reliability of MR Enterography Features for Describing Fibrostenosing Crohn Disease.
Erratum issuedAbstract read
In one paragraph
Article in Radiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 18 papers, 1 of them a synthesis that pooled it.
0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed, 1 synthesis or guideline pooled it.
- ESR Essentials: diagnosis and assessment of treatment response in patients with luminal Crohn's disease-practice recommendations by the European Society of Gastrointestinal and Abdominal Radiology.European radiology · 2025Guideline
- Crohn's Disease Stricture Response to Treatment Assessed with Magnetic Resonance Imaging and Intestinal Ultrasound: STRIDENT Randomized Trial.Inflammatory bowel diseases · 2025Trial
- Visual theranostic oral nanozymes for IBD from principles to preclinical design.Bioactive materials · 2026Review
- Development of a Computed Tomography Enterography-Based Radiomics Model to Characterize Inflammation, Fibrosis, and Smooth Muscle Thickening in Stricturing Crohn's Disease.The American journal of gastroenterology · 2026Article
- Magnetic resonance imaging-based simplified MaRIA scores are associated with future surgery in Crohn's disease, but modest correlation with ileo-colonoscopic inflammation limits their utility in clinical trials: results from the PROFILE trial.Journal of Crohn's & colitis · 2026Article
- Missed strictures and penetrating complications on CT and MR enterography in Crohn's disease patients prior to anti-TNF therapy.Abdominal radiology (New York) · 2026Article
- Toward eliminating missed important findings in fibrostenosing Crohn's disease at CT and MR enterography.Abdominal radiology (New York) · 2026Review
- Magnetic resonance enterography to predict subsequent disabling Crohn's disease in newly diagnosed patients (METRIC-EF)-multivariable prediction model, multicentre diagnostic inception cohort.European radiology · 2025Article
- Crohn Disease Strictures: Multimodality Imaging to Identify Imaging Biomarkers.Radiographics : a review publication of the Radiological Society of North America, Inc · 2025Review
- Beyond Fixed Thresholds: Cluster-Derived MRI Boundaries Improve Assessment of Crohn's Disease Activity.Journal of clinical medicine · 2025Article
- Knowledge and acceptability of the Lémann Index as a tool to measure disease progression and bowel damage in Crohn's disease: results from an international survey.Intestinal research · 2025Article
- Artificial Intelligence-Enabled Clinical Trials in Inflammatory Bowel Disease: Automating and Enhancing Disease Assessment and Study Management.Gastroenterology · 2025Review
- A novel link driving immune cell-fibroblast interactions in intestinal fibrosis.Mucosal immunology · 2025Article
- Fibrosis: cross-organ biology and pathways to development of innovative drugs.Nature reviews. Drug discovery · 2025Review
- SAR Consensus Recommendations for Defining Small Bowel Crohn Disease Strictures at CT and MR Enterography.Radiology · 2025Review
- Artificial intelligence to revolutionize IBD clinical trials: a comprehensive review.Therapeutic advances in gastroenterology · 2025Review
- Article
- Anti-fibrotics in inflammatory bowel diseases: Challenges and successes.Advances in pharmacology (San Diego, Calif.) · 2024Review
Corrections and comments
- Erratum issued
Authors and funding
30 authors.
Florian RiederFrom the Department of Inflammation and Immunity, Lerner Research Institute (F.R., R.O., N.A.), Department of Gastroenterology, Hepatology and Nutrition, Digestive Diseases (F.R., M.T.S., V.C.S.), and Program for Global Translational Inflammatory Bowel Disease Research (F.R., R.O.), Cleveland Clinic Foundation, Cleveland, Ohio; Section of Abdominal Imaging, Imaging, Digestive Diseases and Surgery and Cancer Institutes (M.E.B.) and Department of Diagnostic Radiology (J.M.R.) Cleveland Clinic Foundation, Cleveland, Ohio; Division of Gastroenterology and Hepatology (D.H.B.), Biomedical Imaging Resource (D.R.H.), and Department of Radiology (J.L.F., E.C.E., S.P.S., J.P.H., D.R.H., Y.S.L., J.G.F.), Mayo Clinic, 200 First St, Rochester, MN 55905; Department of Radiology, Shiga University of Medical Science, Shiga, Japan (A.I.); Department of Radiology, University of Texas Medical Branch, Galveston, Tex (P.M.); Centre for Medical Imaging, University College London, London, United Kingdom (S.A.T.); Department of Radiology and Nuclear Medicine, Amsterdam University Medical Centre, University of Amsterdam, Amsterdam, the Netherlands (J.S.); Alimentiv, London, Ontario, Canada (G.Z., Z.W., J. Rémillard, C.M., C.E.P., V.J., B.G.F.); Department of Epidemiology and Biostatistics, Western University, London, Ontario, Canada (G.Z., V.J., B.G.F.); Department of Quantitative Health Sciences, Mayo Clinic, Jacksonville, Fla (R.E.C.); Division of Gastroenterology and Hepatology, University of Calgary, Calgary, Alberta, Canada (C.M.); Departments of Gastroenterology (J.P.) and Radiology (J. Rimola), Hospital Clínic de Barcelona, Barcelona, Spain; and Department of Medicine, Division of Gastroenterology, Western University, London, Ontario, Canada (V.J., B.G.F.).ORCID 0000-0002-9087-1568
Mark E BakerFrom the Department of Inflammation and Immunity, Lerner Research Institute (F.R., R.O., N.A.), Department of Gastroenterology, Hepatology and Nutrition, Digestive Diseases (F.R., M.T.S., V.C.S.), and Program for Global Translational Inflammatory Bowel Disease Research (F.R., R.O.), Cleveland Clinic Foundation, Cleveland, Ohio; Section of Abdominal Imaging, Imaging, Digestive Diseases and Surgery and Cancer Institutes (M.E.B.) and Department of Diagnostic Radiology (J.M.R.) Cleveland Clinic Foundation, Cleveland, Ohio; Division of Gastroenterology and Hepatology (D.H.B.), Biomedical Imaging Resource (D.R.H.), and Department of Radiology (J.L.F., E.C.E., S.P.S., J.P.H., D.R.H., Y.S.L., J.G.F.), Mayo Clinic, 200 First St, Rochester, MN 55905; Department of Radiology, Shiga University of Medical Science, Shiga, Japan (A.I.); Department of Radiology, University of Texas Medical Branch, Galveston, Tex (P.M.); Centre for Medical Imaging, University College London, London, United Kingdom (S.A.T.); Department of Radiology and Nuclear Medicine, Amsterdam University Medical Centre, University of Amsterdam, Amsterdam, the Netherlands (J.S.); Alimentiv, London, Ontario, Canada (G.Z., Z.W., J. Rémillard, C.M., C.E.P., V.J., B.G.F.); Department of Epidemiology and Biostatistics, Western University, London, Ontario, Canada (G.Z., V.J., B.G.F.); Department of Quantitative Health Sciences, Mayo Clinic, Jacksonville, Fla (R.E.C.); Division of Gastroenterology and Hepatology, University of Calgary, Calgary, Alberta, Canada (C.M.); Departments of Gastroenterology (J.P.) and Radiology (J. Rimola), Hospital Clínic de Barcelona, Barcelona, Spain; and Department of Medicine, Division of Gastroenterology, Western University, London, Ontario, Canada (V.J., B.G.F.).ORCID 0000-0001-5023-3361
David H BruiningFrom the Department of Inflammation and Immunity, Lerner Research Institute (F.R., R.O., N.A.), Department of Gastroenterology, Hepatology and Nutrition, Digestive Diseases (F.R., M.T.S., V.C.S.), and Program for Global Translational Inflammatory Bowel Disease Research (F.R., R.O.), Cleveland Clinic Foundation, Cleveland, Ohio; Section of Abdominal Imaging, Imaging, Digestive Diseases and Surgery and Cancer Institutes (M.E.B.) and Department of Diagnostic Radiology (J.M.R.) Cleveland Clinic Foundation, Cleveland, Ohio; Division of Gastroenterology and Hepatology (D.H.B.), Biomedical Imaging Resource (D.R.H.), and Department of Radiology (J.L.F., E.C.E., S.P.S., J.P.H., D.R.H., Y.S.L., J.G.F.), Mayo Clinic, 200 First St, Rochester, MN 55905; Department of Radiology, Shiga University of Medical Science, Shiga, Japan (A.I.); Department of Radiology, University of Texas Medical Branch, Galveston, Tex (P.M.); Centre for Medical Imaging, University College London, London, United Kingdom (S.A.T.); Department of Radiology and Nuclear Medicine, Amsterdam University Medical Centre, University of Amsterdam, Amsterdam, the Netherlands (J.S.); Alimentiv, London, Ontario, Canada (G.Z., Z.W., J. Rémillard, C.M., C.E.P., V.J., B.G.F.); Department of Epidemiology and Biostatistics, Western University, London, Ontario, Canada (G.Z., V.J., B.G.F.); Department of Quantitative Health Sciences, Mayo Clinic, Jacksonville, Fla (R.E.C.); Division of Gastroenterology and Hepatology, University of Calgary, Calgary, Alberta, Canada (C.M.); Departments of Gastroenterology (J.P.) and Radiology (J. Rimola), Hospital Clínic de Barcelona, Barcelona, Spain; and Department of Medicine, Division of Gastroenterology, Western University, London, Ontario, Canada (V.J., B.G.F.).ORCID 0000-0003-4320-8429
Jeff L FidlerFrom the Department of Inflammation and Immunity, Lerner Research Institute (F.R., R.O., N.A.), Department of Gastroenterology, Hepatology and Nutrition, Digestive Diseases (F.R., M.T.S., V.C.S.), and Program for Global Translational Inflammatory Bowel Disease Research (F.R., R.O.), Cleveland Clinic Foundation, Cleveland, Ohio; Section of Abdominal Imaging, Imaging, Digestive Diseases and Surgery and Cancer Institutes (M.E.B.) and Department of Diagnostic Radiology (J.M.R.) Cleveland Clinic Foundation, Cleveland, Ohio; Division of Gastroenterology and Hepatology (D.H.B.), Biomedical Imaging Resource (D.R.H.), and Department of Radiology (J.L.F., E.C.E., S.P.S., J.P.H., D.R.H., Y.S.L., J.G.F.), Mayo Clinic, 200 First St, Rochester, MN 55905; Department of Radiology, Shiga University of Medical Science, Shiga, Japan (A.I.); Department of Radiology, University of Texas Medical Branch, Galveston, Tex (P.M.); Centre for Medical Imaging, University College London, London, United Kingdom (S.A.T.); Department of Radiology and Nuclear Medicine, Amsterdam University Medical Centre, University of Amsterdam, Amsterdam, the Netherlands (J.S.); Alimentiv, London, Ontario, Canada (G.Z., Z.W., J. Rémillard, C.M., C.E.P., V.J., B.G.F.); Department of Epidemiology and Biostatistics, Western University, London, Ontario, Canada (G.Z., V.J., B.G.F.); Department of Quantitative Health Sciences, Mayo Clinic, Jacksonville, Fla (R.E.C.); Division of Gastroenterology and Hepatology, University of Calgary, Calgary, Alberta, Canada (C.M.); Departments of Gastroenterology (J.P.) and Radiology (J. Rimola), Hospital Clínic de Barcelona, Barcelona, Spain; and Department of Medicine, Division of Gastroenterology, Western University, London, Ontario, Canada (V.J., B.G.F.).ORCID 0000-0001-8275-126X
Eric C EhmanFrom the Department of Inflammation and Immunity, Lerner Research Institute (F.R., R.O., N.A.), Department of Gastroenterology, Hepatology and Nutrition, Digestive Diseases (F.R., M.T.S., V.C.S.), and Program for Global Translational Inflammatory Bowel Disease Research (F.R., R.O.), Cleveland Clinic Foundation, Cleveland, Ohio; Section of Abdominal Imaging, Imaging, Digestive Diseases and Surgery and Cancer Institutes (M.E.B.) and Department of Diagnostic Radiology (J.M.R.) Cleveland Clinic Foundation, Cleveland, Ohio; Division of Gastroenterology and Hepatology (D.H.B.), Biomedical Imaging Resource (D.R.H.), and Department of Radiology (J.L.F., E.C.E., S.P.S., J.P.H., D.R.H., Y.S.L., J.G.F.), Mayo Clinic, 200 First St, Rochester, MN 55905; Department of Radiology, Shiga University of Medical Science, Shiga, Japan (A.I.); Department of Radiology, University of Texas Medical Branch, Galveston, Tex (P.M.); Centre for Medical Imaging, University College London, London, United Kingdom (S.A.T.); Department of Radiology and Nuclear Medicine, Amsterdam University Medical Centre, University of Amsterdam, Amsterdam, the Netherlands (J.S.); Alimentiv, London, Ontario, Canada (G.Z., Z.W., J. Rémillard, C.M., C.E.P., V.J., B.G.F.); Department of Epidemiology and Biostatistics, Western University, London, Ontario, Canada (G.Z., V.J., B.G.F.); Department of Quantitative Health Sciences, Mayo Clinic, Jacksonville, Fla (R.E.C.); Division of Gastroenterology and Hepatology, University of Calgary, Calgary, Alberta, Canada (C.M.); Departments of Gastroenterology (J.P.) and Radiology (J. Rimola), Hospital Clínic de Barcelona, Barcelona, Spain; and Department of Medicine, Division of Gastroenterology, Western University, London, Ontario, Canada (V.J., B.G.F.).ORCID 0000-0003-4613-7101
Shannon P SheedyFrom the Department of Inflammation and Immunity, Lerner Research Institute (F.R., R.O., N.A.), Department of Gastroenterology, Hepatology and Nutrition, Digestive Diseases (F.R., M.T.S., V.C.S.), and Program for Global Translational Inflammatory Bowel Disease Research (F.R., R.O.), Cleveland Clinic Foundation, Cleveland, Ohio; Section of Abdominal Imaging, Imaging, Digestive Diseases and Surgery and Cancer Institutes (M.E.B.) and Department of Diagnostic Radiology (J.M.R.) Cleveland Clinic Foundation, Cleveland, Ohio; Division of Gastroenterology and Hepatology (D.H.B.), Biomedical Imaging Resource (D.R.H.), and Department of Radiology (J.L.F., E.C.E., S.P.S., J.P.H., D.R.H., Y.S.L., J.G.F.), Mayo Clinic, 200 First St, Rochester, MN 55905; Department of Radiology, Shiga University of Medical Science, Shiga, Japan (A.I.); Department of Radiology, University of Texas Medical Branch, Galveston, Tex (P.M.); Centre for Medical Imaging, University College London, London, United Kingdom (S.A.T.); Department of Radiology and Nuclear Medicine, Amsterdam University Medical Centre, University of Amsterdam, Amsterdam, the Netherlands (J.S.); Alimentiv, London, Ontario, Canada (G.Z., Z.W., J. Rémillard, C.M., C.E.P., V.J., B.G.F.); Department of Epidemiology and Biostatistics, Western University, London, Ontario, Canada (G.Z., V.J., B.G.F.); Department of Quantitative Health Sciences, Mayo Clinic, Jacksonville, Fla (R.E.C.); Division of Gastroenterology and Hepatology, University of Calgary, Calgary, Alberta, Canada (C.M.); Departments of Gastroenterology (J.P.) and Radiology (J. Rimola), Hospital Clínic de Barcelona, Barcelona, Spain; and Department of Medicine, Division of Gastroenterology, Western University, London, Ontario, Canada (V.J., B.G.F.).ORCID 0000-0002-7712-8278
Jay P HeikenFrom the Department of Inflammation and Immunity, Lerner Research Institute (F.R., R.O., N.A.), Department of Gastroenterology, Hepatology and Nutrition, Digestive Diseases (F.R., M.T.S., V.C.S.), and Program for Global Translational Inflammatory Bowel Disease Research (F.R., R.O.), Cleveland Clinic Foundation, Cleveland, Ohio; Section of Abdominal Imaging, Imaging, Digestive Diseases and Surgery and Cancer Institutes (M.E.B.) and Department of Diagnostic Radiology (J.M.R.) Cleveland Clinic Foundation, Cleveland, Ohio; Division of Gastroenterology and Hepatology (D.H.B.), Biomedical Imaging Resource (D.R.H.), and Department of Radiology (J.L.F., E.C.E., S.P.S., J.P.H., D.R.H., Y.S.L., J.G.F.), Mayo Clinic, 200 First St, Rochester, MN 55905; Department of Radiology, Shiga University of Medical Science, Shiga, Japan (A.I.); Department of Radiology, University of Texas Medical Branch, Galveston, Tex (P.M.); Centre for Medical Imaging, University College London, London, United Kingdom (S.A.T.); Department of Radiology and Nuclear Medicine, Amsterdam University Medical Centre, University of Amsterdam, Amsterdam, the Netherlands (J.S.); Alimentiv, London, Ontario, Canada (G.Z., Z.W., J. Rémillard, C.M., C.E.P., V.J., B.G.F.); Department of Epidemiology and Biostatistics, Western University, London, Ontario, Canada (G.Z., V.J., B.G.F.); Department of Quantitative Health Sciences, Mayo Clinic, Jacksonville, Fla (R.E.C.); Division of Gastroenterology and Hepatology, University of Calgary, Calgary, Alberta, Canada (C.M.); Departments of Gastroenterology (J.P.) and Radiology (J. Rimola), Hospital Clínic de Barcelona, Barcelona, Spain; and Department of Medicine, Division of Gastroenterology, Western University, London, Ontario, Canada (V.J., B.G.F.).ORCID 0000-0003-4488-2888
Justin M ReamFrom the Department of Inflammation and Immunity, Lerner Research Institute (F.R., R.O., N.A.), Department of Gastroenterology, Hepatology and Nutrition, Digestive Diseases (F.R., M.T.S., V.C.S.), and Program for Global Translational Inflammatory Bowel Disease Research (F.R., R.O.), Cleveland Clinic Foundation, Cleveland, Ohio; Section of Abdominal Imaging, Imaging, Digestive Diseases and Surgery and Cancer Institutes (M.E.B.) and Department of Diagnostic Radiology (J.M.R.) Cleveland Clinic Foundation, Cleveland, Ohio; Division of Gastroenterology and Hepatology (D.H.B.), Biomedical Imaging Resource (D.R.H.), and Department of Radiology (J.L.F., E.C.E., S.P.S., J.P.H., D.R.H., Y.S.L., J.G.F.), Mayo Clinic, 200 First St, Rochester, MN 55905; Department of Radiology, Shiga University of Medical Science, Shiga, Japan (A.I.); Department of Radiology, University of Texas Medical Branch, Galveston, Tex (P.M.); Centre for Medical Imaging, University College London, London, United Kingdom (S.A.T.); Department of Radiology and Nuclear Medicine, Amsterdam University Medical Centre, University of Amsterdam, Amsterdam, the Netherlands (J.S.); Alimentiv, London, Ontario, Canada (G.Z., Z.W., J. Rémillard, C.M., C.E.P., V.J., B.G.F.); Department of Epidemiology and Biostatistics, Western University, London, Ontario, Canada (G.Z., V.J., B.G.F.); Department of Quantitative Health Sciences, Mayo Clinic, Jacksonville, Fla (R.E.C.); Division of Gastroenterology and Hepatology, University of Calgary, Calgary, Alberta, Canada (C.M.); Departments of Gastroenterology (J.P.) and Radiology (J. Rimola), Hospital Clínic de Barcelona, Barcelona, Spain; and Department of Medicine, Division of Gastroenterology, Western University, London, Ontario, Canada (V.J., B.G.F.).ORCID 0000-0003-1223-9054
David R HolmesFrom the Department of Inflammation and Immunity, Lerner Research Institute (F.R., R.O., N.A.), Department of Gastroenterology, Hepatology and Nutrition, Digestive Diseases (F.R., M.T.S., V.C.S.), and Program for Global Translational Inflammatory Bowel Disease Research (F.R., R.O.), Cleveland Clinic Foundation, Cleveland, Ohio; Section of Abdominal Imaging, Imaging, Digestive Diseases and Surgery and Cancer Institutes (M.E.B.) and Department of Diagnostic Radiology (J.M.R.) Cleveland Clinic Foundation, Cleveland, Ohio; Division of Gastroenterology and Hepatology (D.H.B.), Biomedical Imaging Resource (D.R.H.), and Department of Radiology (J.L.F., E.C.E., S.P.S., J.P.H., D.R.H., Y.S.L., J.G.F.), Mayo Clinic, 200 First St, Rochester, MN 55905; Department of Radiology, Shiga University of Medical Science, Shiga, Japan (A.I.); Department of Radiology, University of Texas Medical Branch, Galveston, Tex (P.M.); Centre for Medical Imaging, University College London, London, United Kingdom (S.A.T.); Department of Radiology and Nuclear Medicine, Amsterdam University Medical Centre, University of Amsterdam, Amsterdam, the Netherlands (J.S.); Alimentiv, London, Ontario, Canada (G.Z., Z.W., J. Rémillard, C.M., C.E.P., V.J., B.G.F.); Department of Epidemiology and Biostatistics, Western University, London, Ontario, Canada (G.Z., V.J., B.G.F.); Department of Quantitative Health Sciences, Mayo Clinic, Jacksonville, Fla (R.E.C.); Division of Gastroenterology and Hepatology, University of Calgary, Calgary, Alberta, Canada (C.M.); Departments of Gastroenterology (J.P.) and Radiology (J. Rimola), Hospital Clínic de Barcelona, Barcelona, Spain; and Department of Medicine, Division of Gastroenterology, Western University, London, Ontario, Canada (V.J., B.G.F.).
Akitoshi InoueFrom the Department of Inflammation and Immunity, Lerner Research Institute (F.R., R.O., N.A.), Department of Gastroenterology, Hepatology and Nutrition, Digestive Diseases (F.R., M.T.S., V.C.S.), and Program for Global Translational Inflammatory Bowel Disease Research (F.R., R.O.), Cleveland Clinic Foundation, Cleveland, Ohio; Section of Abdominal Imaging, Imaging, Digestive Diseases and Surgery and Cancer Institutes (M.E.B.) and Department of Diagnostic Radiology (J.M.R.) Cleveland Clinic Foundation, Cleveland, Ohio; Division of Gastroenterology and Hepatology (D.H.B.), Biomedical Imaging Resource (D.R.H.), and Department of Radiology (J.L.F., E.C.E., S.P.S., J.P.H., D.R.H., Y.S.L., J.G.F.), Mayo Clinic, 200 First St, Rochester, MN 55905; Department of Radiology, Shiga University of Medical Science, Shiga, Japan (A.I.); Department of Radiology, University of Texas Medical Branch, Galveston, Tex (P.M.); Centre for Medical Imaging, University College London, London, United Kingdom (S.A.T.); Department of Radiology and Nuclear Medicine, Amsterdam University Medical Centre, University of Amsterdam, Amsterdam, the Netherlands (J.S.); Alimentiv, London, Ontario, Canada (G.Z., Z.W., J. Rémillard, C.M., C.E.P., V.J., B.G.F.); Department of Epidemiology and Biostatistics, Western University, London, Ontario, Canada (G.Z., V.J., B.G.F.); Department of Quantitative Health Sciences, Mayo Clinic, Jacksonville, Fla (R.E.C.); Division of Gastroenterology and Hepatology, University of Calgary, Calgary, Alberta, Canada (C.M.); Departments of Gastroenterology (J.P.) and Radiology (J. Rimola), Hospital Clínic de Barcelona, Barcelona, Spain; and Department of Medicine, Division of Gastroenterology, Western University, London, Ontario, Canada (V.J., B.G.F.).
Payam MohammadinejadFrom the Department of Inflammation and Immunity, Lerner Research Institute (F.R., R.O., N.A.), Department of Gastroenterology, Hepatology and Nutrition, Digestive Diseases (F.R., M.T.S., V.C.S.), and Program for Global Translational Inflammatory Bowel Disease Research (F.R., R.O.), Cleveland Clinic Foundation, Cleveland, Ohio; Section of Abdominal Imaging, Imaging, Digestive Diseases and Surgery and Cancer Institutes (M.E.B.) and Department of Diagnostic Radiology (J.M.R.) Cleveland Clinic Foundation, Cleveland, Ohio; Division of Gastroenterology and Hepatology (D.H.B.), Biomedical Imaging Resource (D.R.H.), and Department of Radiology (J.L.F., E.C.E., S.P.S., J.P.H., D.R.H., Y.S.L., J.G.F.), Mayo Clinic, 200 First St, Rochester, MN 55905; Department of Radiology, Shiga University of Medical Science, Shiga, Japan (A.I.); Department of Radiology, University of Texas Medical Branch, Galveston, Tex (P.M.); Centre for Medical Imaging, University College London, London, United Kingdom (S.A.T.); Department of Radiology and Nuclear Medicine, Amsterdam University Medical Centre, University of Amsterdam, Amsterdam, the Netherlands (J.S.); Alimentiv, London, Ontario, Canada (G.Z., Z.W., J. Rémillard, C.M., C.E.P., V.J., B.G.F.); Department of Epidemiology and Biostatistics, Western University, London, Ontario, Canada (G.Z., V.J., B.G.F.); Department of Quantitative Health Sciences, Mayo Clinic, Jacksonville, Fla (R.E.C.); Division of Gastroenterology and Hepatology, University of Calgary, Calgary, Alberta, Canada (C.M.); Departments of Gastroenterology (J.P.) and Radiology (J. Rimola), Hospital Clínic de Barcelona, Barcelona, Spain; and Department of Medicine, Division of Gastroenterology, Western University, London, Ontario, Canada (V.J., B.G.F.).
Yong S LeeFrom the Department of Inflammation and Immunity, Lerner Research Institute (F.R., R.O., N.A.), Department of Gastroenterology, Hepatology and Nutrition, Digestive Diseases (F.R., M.T.S., V.C.S.), and Program for Global Translational Inflammatory Bowel Disease Research (F.R., R.O.), Cleveland Clinic Foundation, Cleveland, Ohio; Section of Abdominal Imaging, Imaging, Digestive Diseases and Surgery and Cancer Institutes (M.E.B.) and Department of Diagnostic Radiology (J.M.R.) Cleveland Clinic Foundation, Cleveland, Ohio; Division of Gastroenterology and Hepatology (D.H.B.), Biomedical Imaging Resource (D.R.H.), and Department of Radiology (J.L.F., E.C.E., S.P.S., J.P.H., D.R.H., Y.S.L., J.G.F.), Mayo Clinic, 200 First St, Rochester, MN 55905; Department of Radiology, Shiga University of Medical Science, Shiga, Japan (A.I.); Department of Radiology, University of Texas Medical Branch, Galveston, Tex (P.M.); Centre for Medical Imaging, University College London, London, United Kingdom (S.A.T.); Department of Radiology and Nuclear Medicine, Amsterdam University Medical Centre, University of Amsterdam, Amsterdam, the Netherlands (J.S.); Alimentiv, London, Ontario, Canada (G.Z., Z.W., J. Rémillard, C.M., C.E.P., V.J., B.G.F.); Department of Epidemiology and Biostatistics, Western University, London, Ontario, Canada (G.Z., V.J., B.G.F.); Department of Quantitative Health Sciences, Mayo Clinic, Jacksonville, Fla (R.E.C.); Division of Gastroenterology and Hepatology, University of Calgary, Calgary, Alberta, Canada (C.M.); Departments of Gastroenterology (J.P.) and Radiology (J. Rimola), Hospital Clínic de Barcelona, Barcelona, Spain; and Department of Medicine, Division of Gastroenterology, Western University, London, Ontario, Canada (V.J., B.G.F.).ORCID 0009-0005-9707-144X
Stuart A TaylorFrom the Department of Inflammation and Immunity, Lerner Research Institute (F.R., R.O., N.A.), Department of Gastroenterology, Hepatology and Nutrition, Digestive Diseases (F.R., M.T.S., V.C.S.), and Program for Global Translational Inflammatory Bowel Disease Research (F.R., R.O.), Cleveland Clinic Foundation, Cleveland, Ohio; Section of Abdominal Imaging, Imaging, Digestive Diseases and Surgery and Cancer Institutes (M.E.B.) and Department of Diagnostic Radiology (J.M.R.) Cleveland Clinic Foundation, Cleveland, Ohio; Division of Gastroenterology and Hepatology (D.H.B.), Biomedical Imaging Resource (D.R.H.), and Department of Radiology (J.L.F., E.C.E., S.P.S., J.P.H., D.R.H., Y.S.L., J.G.F.), Mayo Clinic, 200 First St, Rochester, MN 55905; Department of Radiology, Shiga University of Medical Science, Shiga, Japan (A.I.); Department of Radiology, University of Texas Medical Branch, Galveston, Tex (P.M.); Centre for Medical Imaging, University College London, London, United Kingdom (S.A.T.); Department of Radiology and Nuclear Medicine, Amsterdam University Medical Centre, University of Amsterdam, Amsterdam, the Netherlands (J.S.); Alimentiv, London, Ontario, Canada (G.Z., Z.W., J. Rémillard, C.M., C.E.P., V.J., B.G.F.); Department of Epidemiology and Biostatistics, Western University, London, Ontario, Canada (G.Z., V.J., B.G.F.); Department of Quantitative Health Sciences, Mayo Clinic, Jacksonville, Fla (R.E.C.); Division of Gastroenterology and Hepatology, University of Calgary, Calgary, Alberta, Canada (C.M.); Departments of Gastroenterology (J.P.) and Radiology (J. Rimola), Hospital Clínic de Barcelona, Barcelona, Spain; and Department of Medicine, Division of Gastroenterology, Western University, London, Ontario, Canada (V.J., B.G.F.).
Jaap StokerFrom the Department of Inflammation and Immunity, Lerner Research Institute (F.R., R.O., N.A.), Department of Gastroenterology, Hepatology and Nutrition, Digestive Diseases (F.R., M.T.S., V.C.S.), and Program for Global Translational Inflammatory Bowel Disease Research (F.R., R.O.), Cleveland Clinic Foundation, Cleveland, Ohio; Section of Abdominal Imaging, Imaging, Digestive Diseases and Surgery and Cancer Institutes (M.E.B.) and Department of Diagnostic Radiology (J.M.R.) Cleveland Clinic Foundation, Cleveland, Ohio; Division of Gastroenterology and Hepatology (D.H.B.), Biomedical Imaging Resource (D.R.H.), and Department of Radiology (J.L.F., E.C.E., S.P.S., J.P.H., D.R.H., Y.S.L., J.G.F.), Mayo Clinic, 200 First St, Rochester, MN 55905; Department of Radiology, Shiga University of Medical Science, Shiga, Japan (A.I.); Department of Radiology, University of Texas Medical Branch, Galveston, Tex (P.M.); Centre for Medical Imaging, University College London, London, United Kingdom (S.A.T.); Department of Radiology and Nuclear Medicine, Amsterdam University Medical Centre, University of Amsterdam, Amsterdam, the Netherlands (J.S.); Alimentiv, London, Ontario, Canada (G.Z., Z.W., J. Rémillard, C.M., C.E.P., V.J., B.G.F.); Department of Epidemiology and Biostatistics, Western University, London, Ontario, Canada (G.Z., V.J., B.G.F.); Department of Quantitative Health Sciences, Mayo Clinic, Jacksonville, Fla (R.E.C.); Division of Gastroenterology and Hepatology, University of Calgary, Calgary, Alberta, Canada (C.M.); Departments of Gastroenterology (J.P.) and Radiology (J. Rimola), Hospital Clínic de Barcelona, Barcelona, Spain; and Department of Medicine, Division of Gastroenterology, Western University, London, Ontario, Canada (V.J., B.G.F.).ORCID 0000-0002-9822-3784
Guangyong ZouFrom the Department of Inflammation and Immunity, Lerner Research Institute (F.R., R.O., N.A.), Department of Gastroenterology, Hepatology and Nutrition, Digestive Diseases (F.R., M.T.S., V.C.S.), and Program for Global Translational Inflammatory Bowel Disease Research (F.R., R.O.), Cleveland Clinic Foundation, Cleveland, Ohio; Section of Abdominal Imaging, Imaging, Digestive Diseases and Surgery and Cancer Institutes (M.E.B.) and Department of Diagnostic Radiology (J.M.R.) Cleveland Clinic Foundation, Cleveland, Ohio; Division of Gastroenterology and Hepatology (D.H.B.), Biomedical Imaging Resource (D.R.H.), and Department of Radiology (J.L.F., E.C.E., S.P.S., J.P.H., D.R.H., Y.S.L., J.G.F.), Mayo Clinic, 200 First St, Rochester, MN 55905; Department of Radiology, Shiga University of Medical Science, Shiga, Japan (A.I.); Department of Radiology, University of Texas Medical Branch, Galveston, Tex (P.M.); Centre for Medical Imaging, University College London, London, United Kingdom (S.A.T.); Department of Radiology and Nuclear Medicine, Amsterdam University Medical Centre, University of Amsterdam, Amsterdam, the Netherlands (J.S.); Alimentiv, London, Ontario, Canada (G.Z., Z.W., J. Rémillard, C.M., C.E.P., V.J., B.G.F.); Department of Epidemiology and Biostatistics, Western University, London, Ontario, Canada (G.Z., V.J., B.G.F.); Department of Quantitative Health Sciences, Mayo Clinic, Jacksonville, Fla (R.E.C.); Division of Gastroenterology and Hepatology, University of Calgary, Calgary, Alberta, Canada (C.M.); Departments of Gastroenterology (J.P.) and Radiology (J. Rimola), Hospital Clínic de Barcelona, Barcelona, Spain; and Department of Medicine, Division of Gastroenterology, Western University, London, Ontario, Canada (V.J., B.G.F.).ORCID 0000-0001-5773-4185
Zhongya WangFrom the Department of Inflammation and Immunity, Lerner Research Institute (F.R., R.O., N.A.), Department of Gastroenterology, Hepatology and Nutrition, Digestive Diseases (F.R., M.T.S., V.C.S.), and Program for Global Translational Inflammatory Bowel Disease Research (F.R., R.O.), Cleveland Clinic Foundation, Cleveland, Ohio; Section of Abdominal Imaging, Imaging, Digestive Diseases and Surgery and Cancer Institutes (M.E.B.) and Department of Diagnostic Radiology (J.M.R.) Cleveland Clinic Foundation, Cleveland, Ohio; Division of Gastroenterology and Hepatology (D.H.B.), Biomedical Imaging Resource (D.R.H.), and Department of Radiology (J.L.F., E.C.E., S.P.S., J.P.H., D.R.H., Y.S.L., J.G.F.), Mayo Clinic, 200 First St, Rochester, MN 55905; Department of Radiology, Shiga University of Medical Science, Shiga, Japan (A.I.); Department of Radiology, University of Texas Medical Branch, Galveston, Tex (P.M.); Centre for Medical Imaging, University College London, London, United Kingdom (S.A.T.); Department of Radiology and Nuclear Medicine, Amsterdam University Medical Centre, University of Amsterdam, Amsterdam, the Netherlands (J.S.); Alimentiv, London, Ontario, Canada (G.Z., Z.W., J. Rémillard, C.M., C.E.P., V.J., B.G.F.); Department of Epidemiology and Biostatistics, Western University, London, Ontario, Canada (G.Z., V.J., B.G.F.); Department of Quantitative Health Sciences, Mayo Clinic, Jacksonville, Fla (R.E.C.); Division of Gastroenterology and Hepatology, University of Calgary, Calgary, Alberta, Canada (C.M.); Departments of Gastroenterology (J.P.) and Radiology (J. Rimola), Hospital Clínic de Barcelona, Barcelona, Spain; and Department of Medicine, Division of Gastroenterology, Western University, London, Ontario, Canada (V.J., B.G.F.).ORCID 0000-0002-3866-8052
Julie RémillardFrom the Department of Inflammation and Immunity, Lerner Research Institute (F.R., R.O., N.A.), Department of Gastroenterology, Hepatology and Nutrition, Digestive Diseases (F.R., M.T.S., V.C.S.), and Program for Global Translational Inflammatory Bowel Disease Research (F.R., R.O.), Cleveland Clinic Foundation, Cleveland, Ohio; Section of Abdominal Imaging, Imaging, Digestive Diseases and Surgery and Cancer Institutes (M.E.B.) and Department of Diagnostic Radiology (J.M.R.) Cleveland Clinic Foundation, Cleveland, Ohio; Division of Gastroenterology and Hepatology (D.H.B.), Biomedical Imaging Resource (D.R.H.), and Department of Radiology (J.L.F., E.C.E., S.P.S., J.P.H., D.R.H., Y.S.L., J.G.F.), Mayo Clinic, 200 First St, Rochester, MN 55905; Department of Radiology, Shiga University of Medical Science, Shiga, Japan (A.I.); Department of Radiology, University of Texas Medical Branch, Galveston, Tex (P.M.); Centre for Medical Imaging, University College London, London, United Kingdom (S.A.T.); Department of Radiology and Nuclear Medicine, Amsterdam University Medical Centre, University of Amsterdam, Amsterdam, the Netherlands (J.S.); Alimentiv, London, Ontario, Canada (G.Z., Z.W., J. Rémillard, C.M., C.E.P., V.J., B.G.F.); Department of Epidemiology and Biostatistics, Western University, London, Ontario, Canada (G.Z., V.J., B.G.F.); Department of Quantitative Health Sciences, Mayo Clinic, Jacksonville, Fla (R.E.C.); Division of Gastroenterology and Hepatology, University of Calgary, Calgary, Alberta, Canada (C.M.); Departments of Gastroenterology (J.P.) and Radiology (J. Rimola), Hospital Clínic de Barcelona, Barcelona, Spain; and Department of Medicine, Division of Gastroenterology, Western University, London, Ontario, Canada (V.J., B.G.F.).
Rickey E CarterFrom the Department of Inflammation and Immunity, Lerner Research Institute (F.R., R.O., N.A.), Department of Gastroenterology, Hepatology and Nutrition, Digestive Diseases (F.R., M.T.S., V.C.S.), and Program for Global Translational Inflammatory Bowel Disease Research (F.R., R.O.), Cleveland Clinic Foundation, Cleveland, Ohio; Section of Abdominal Imaging, Imaging, Digestive Diseases and Surgery and Cancer Institutes (M.E.B.) and Department of Diagnostic Radiology (J.M.R.) Cleveland Clinic Foundation, Cleveland, Ohio; Division of Gastroenterology and Hepatology (D.H.B.), Biomedical Imaging Resource (D.R.H.), and Department of Radiology (J.L.F., E.C.E., S.P.S., J.P.H., D.R.H., Y.S.L., J.G.F.), Mayo Clinic, 200 First St, Rochester, MN 55905; Department of Radiology, Shiga University of Medical Science, Shiga, Japan (A.I.); Department of Radiology, University of Texas Medical Branch, Galveston, Tex (P.M.); Centre for Medical Imaging, University College London, London, United Kingdom (S.A.T.); Department of Radiology and Nuclear Medicine, Amsterdam University Medical Centre, University of Amsterdam, Amsterdam, the Netherlands (J.S.); Alimentiv, London, Ontario, Canada (G.Z., Z.W., J. Rémillard, C.M., C.E.P., V.J., B.G.F.); Department of Epidemiology and Biostatistics, Western University, London, Ontario, Canada (G.Z., V.J., B.G.F.); Department of Quantitative Health Sciences, Mayo Clinic, Jacksonville, Fla (R.E.C.); Division of Gastroenterology and Hepatology, University of Calgary, Calgary, Alberta, Canada (C.M.); Departments of Gastroenterology (J.P.) and Radiology (J. Rimola), Hospital Clínic de Barcelona, Barcelona, Spain; and Department of Medicine, Division of Gastroenterology, Western University, London, Ontario, Canada (V.J., B.G.F.).ORCID 0000-0002-0818-273X
Ronald OttichiloFrom the Department of Inflammation and Immunity, Lerner Research Institute (F.R., R.O., N.A.), Department of Gastroenterology, Hepatology and Nutrition, Digestive Diseases (F.R., M.T.S., V.C.S.), and Program for Global Translational Inflammatory Bowel Disease Research (F.R., R.O.), Cleveland Clinic Foundation, Cleveland, Ohio; Section of Abdominal Imaging, Imaging, Digestive Diseases and Surgery and Cancer Institutes (M.E.B.) and Department of Diagnostic Radiology (J.M.R.) Cleveland Clinic Foundation, Cleveland, Ohio; Division of Gastroenterology and Hepatology (D.H.B.), Biomedical Imaging Resource (D.R.H.), and Department of Radiology (J.L.F., E.C.E., S.P.S., J.P.H., D.R.H., Y.S.L., J.G.F.), Mayo Clinic, 200 First St, Rochester, MN 55905; Department of Radiology, Shiga University of Medical Science, Shiga, Japan (A.I.); Department of Radiology, University of Texas Medical Branch, Galveston, Tex (P.M.); Centre for Medical Imaging, University College London, London, United Kingdom (S.A.T.); Department of Radiology and Nuclear Medicine, Amsterdam University Medical Centre, University of Amsterdam, Amsterdam, the Netherlands (J.S.); Alimentiv, London, Ontario, Canada (G.Z., Z.W., J. Rémillard, C.M., C.E.P., V.J., B.G.F.); Department of Epidemiology and Biostatistics, Western University, London, Ontario, Canada (G.Z., V.J., B.G.F.); Department of Quantitative Health Sciences, Mayo Clinic, Jacksonville, Fla (R.E.C.); Division of Gastroenterology and Hepatology, University of Calgary, Calgary, Alberta, Canada (C.M.); Departments of Gastroenterology (J.P.) and Radiology (J. Rimola), Hospital Clínic de Barcelona, Barcelona, Spain; and Department of Medicine, Division of Gastroenterology, Western University, London, Ontario, Canada (V.J., B.G.F.).
Norma AtkinsonFrom the Department of Inflammation and Immunity, Lerner Research Institute (F.R., R.O., N.A.), Department of Gastroenterology, Hepatology and Nutrition, Digestive Diseases (F.R., M.T.S., V.C.S.), and Program for Global Translational Inflammatory Bowel Disease Research (F.R., R.O.), Cleveland Clinic Foundation, Cleveland, Ohio; Section of Abdominal Imaging, Imaging, Digestive Diseases and Surgery and Cancer Institutes (M.E.B.) and Department of Diagnostic Radiology (J.M.R.) Cleveland Clinic Foundation, Cleveland, Ohio; Division of Gastroenterology and Hepatology (D.H.B.), Biomedical Imaging Resource (D.R.H.), and Department of Radiology (J.L.F., E.C.E., S.P.S., J.P.H., D.R.H., Y.S.L., J.G.F.), Mayo Clinic, 200 First St, Rochester, MN 55905; Department of Radiology, Shiga University of Medical Science, Shiga, Japan (A.I.); Department of Radiology, University of Texas Medical Branch, Galveston, Tex (P.M.); Centre for Medical Imaging, University College London, London, United Kingdom (S.A.T.); Department of Radiology and Nuclear Medicine, Amsterdam University Medical Centre, University of Amsterdam, Amsterdam, the Netherlands (J.S.); Alimentiv, London, Ontario, Canada (G.Z., Z.W., J. Rémillard, C.M., C.E.P., V.J., B.G.F.); Department of Epidemiology and Biostatistics, Western University, London, Ontario, Canada (G.Z., V.J., B.G.F.); Department of Quantitative Health Sciences, Mayo Clinic, Jacksonville, Fla (R.E.C.); Division of Gastroenterology and Hepatology, University of Calgary, Calgary, Alberta, Canada (C.M.); Departments of Gastroenterology (J.P.) and Radiology (J. Rimola), Hospital Clínic de Barcelona, Barcelona, Spain; and Department of Medicine, Division of Gastroenterology, Western University, London, Ontario, Canada (V.J., B.G.F.).ORCID 0009-0002-9679-8004
Mohamed Tausif SiddiquiFrom the Department of Inflammation and Immunity, Lerner Research Institute (F.R., R.O., N.A.), Department of Gastroenterology, Hepatology and Nutrition, Digestive Diseases (F.R., M.T.S., V.C.S.), and Program for Global Translational Inflammatory Bowel Disease Research (F.R., R.O.), Cleveland Clinic Foundation, Cleveland, Ohio; Section of Abdominal Imaging, Imaging, Digestive Diseases and Surgery and Cancer Institutes (M.E.B.) and Department of Diagnostic Radiology (J.M.R.) Cleveland Clinic Foundation, Cleveland, Ohio; Division of Gastroenterology and Hepatology (D.H.B.), Biomedical Imaging Resource (D.R.H.), and Department of Radiology (J.L.F., E.C.E., S.P.S., J.P.H., D.R.H., Y.S.L., J.G.F.), Mayo Clinic, 200 First St, Rochester, MN 55905; Department of Radiology, Shiga University of Medical Science, Shiga, Japan (A.I.); Department of Radiology, University of Texas Medical Branch, Galveston, Tex (P.M.); Centre for Medical Imaging, University College London, London, United Kingdom (S.A.T.); Department of Radiology and Nuclear Medicine, Amsterdam University Medical Centre, University of Amsterdam, Amsterdam, the Netherlands (J.S.); Alimentiv, London, Ontario, Canada (G.Z., Z.W., J. Rémillard, C.M., C.E.P., V.J., B.G.F.); Department of Epidemiology and Biostatistics, Western University, London, Ontario, Canada (G.Z., V.J., B.G.F.); Department of Quantitative Health Sciences, Mayo Clinic, Jacksonville, Fla (R.E.C.); Division of Gastroenterology and Hepatology, University of Calgary, Calgary, Alberta, Canada (C.M.); Departments of Gastroenterology (J.P.) and Radiology (J. Rimola), Hospital Clínic de Barcelona, Barcelona, Spain; and Department of Medicine, Division of Gastroenterology, Western University, London, Ontario, Canada (V.J., B.G.F.).ORCID 0000-0003-0778-2319
Venkata C SunkesulaFrom the Department of Inflammation and Immunity, Lerner Research Institute (F.R., R.O., N.A.), Department of Gastroenterology, Hepatology and Nutrition, Digestive Diseases (F.R., M.T.S., V.C.S.), and Program for Global Translational Inflammatory Bowel Disease Research (F.R., R.O.), Cleveland Clinic Foundation, Cleveland, Ohio; Section of Abdominal Imaging, Imaging, Digestive Diseases and Surgery and Cancer Institutes (M.E.B.) and Department of Diagnostic Radiology (J.M.R.) Cleveland Clinic Foundation, Cleveland, Ohio; Division of Gastroenterology and Hepatology (D.H.B.), Biomedical Imaging Resource (D.R.H.), and Department of Radiology (J.L.F., E.C.E., S.P.S., J.P.H., D.R.H., Y.S.L., J.G.F.), Mayo Clinic, 200 First St, Rochester, MN 55905; Department of Radiology, Shiga University of Medical Science, Shiga, Japan (A.I.); Department of Radiology, University of Texas Medical Branch, Galveston, Tex (P.M.); Centre for Medical Imaging, University College London, London, United Kingdom (S.A.T.); Department of Radiology and Nuclear Medicine, Amsterdam University Medical Centre, University of Amsterdam, Amsterdam, the Netherlands (J.S.); Alimentiv, London, Ontario, Canada (G.Z., Z.W., J. Rémillard, C.M., C.E.P., V.J., B.G.F.); Department of Epidemiology and Biostatistics, Western University, London, Ontario, Canada (G.Z., V.J., B.G.F.); Department of Quantitative Health Sciences, Mayo Clinic, Jacksonville, Fla (R.E.C.); Division of Gastroenterology and Hepatology, University of Calgary, Calgary, Alberta, Canada (C.M.); Departments of Gastroenterology (J.P.) and Radiology (J. Rimola), Hospital Clínic de Barcelona, Barcelona, Spain; and Department of Medicine, Division of Gastroenterology, Western University, London, Ontario, Canada (V.J., B.G.F.).
Christopher MaFrom the Department of Inflammation and Immunity, Lerner Research Institute (F.R., R.O., N.A.), Department of Gastroenterology, Hepatology and Nutrition, Digestive Diseases (F.R., M.T.S., V.C.S.), and Program for Global Translational Inflammatory Bowel Disease Research (F.R., R.O.), Cleveland Clinic Foundation, Cleveland, Ohio; Section of Abdominal Imaging, Imaging, Digestive Diseases and Surgery and Cancer Institutes (M.E.B.) and Department of Diagnostic Radiology (J.M.R.) Cleveland Clinic Foundation, Cleveland, Ohio; Division of Gastroenterology and Hepatology (D.H.B.), Biomedical Imaging Resource (D.R.H.), and Department of Radiology (J.L.F., E.C.E., S.P.S., J.P.H., D.R.H., Y.S.L., J.G.F.), Mayo Clinic, 200 First St, Rochester, MN 55905; Department of Radiology, Shiga University of Medical Science, Shiga, Japan (A.I.); Department of Radiology, University of Texas Medical Branch, Galveston, Tex (P.M.); Centre for Medical Imaging, University College London, London, United Kingdom (S.A.T.); Department of Radiology and Nuclear Medicine, Amsterdam University Medical Centre, University of Amsterdam, Amsterdam, the Netherlands (J.S.); Alimentiv, London, Ontario, Canada (G.Z., Z.W., J. Rémillard, C.M., C.E.P., V.J., B.G.F.); Department of Epidemiology and Biostatistics, Western University, London, Ontario, Canada (G.Z., V.J., B.G.F.); Department of Quantitative Health Sciences, Mayo Clinic, Jacksonville, Fla (R.E.C.); Division of Gastroenterology and Hepatology, University of Calgary, Calgary, Alberta, Canada (C.M.); Departments of Gastroenterology (J.P.) and Radiology (J. Rimola), Hospital Clínic de Barcelona, Barcelona, Spain; and Department of Medicine, Division of Gastroenterology, Western University, London, Ontario, Canada (V.J., B.G.F.).
Claire E ParkerFrom the Department of Inflammation and Immunity, Lerner Research Institute (F.R., R.O., N.A.), Department of Gastroenterology, Hepatology and Nutrition, Digestive Diseases (F.R., M.T.S., V.C.S.), and Program for Global Translational Inflammatory Bowel Disease Research (F.R., R.O.), Cleveland Clinic Foundation, Cleveland, Ohio; Section of Abdominal Imaging, Imaging, Digestive Diseases and Surgery and Cancer Institutes (M.E.B.) and Department of Diagnostic Radiology (J.M.R.) Cleveland Clinic Foundation, Cleveland, Ohio; Division of Gastroenterology and Hepatology (D.H.B.), Biomedical Imaging Resource (D.R.H.), and Department of Radiology (J.L.F., E.C.E., S.P.S., J.P.H., D.R.H., Y.S.L., J.G.F.), Mayo Clinic, 200 First St, Rochester, MN 55905; Department of Radiology, Shiga University of Medical Science, Shiga, Japan (A.I.); Department of Radiology, University of Texas Medical Branch, Galveston, Tex (P.M.); Centre for Medical Imaging, University College London, London, United Kingdom (S.A.T.); Department of Radiology and Nuclear Medicine, Amsterdam University Medical Centre, University of Amsterdam, Amsterdam, the Netherlands (J.S.); Alimentiv, London, Ontario, Canada (G.Z., Z.W., J. Rémillard, C.M., C.E.P., V.J., B.G.F.); Department of Epidemiology and Biostatistics, Western University, London, Ontario, Canada (G.Z., V.J., B.G.F.); Department of Quantitative Health Sciences, Mayo Clinic, Jacksonville, Fla (R.E.C.); Division of Gastroenterology and Hepatology, University of Calgary, Calgary, Alberta, Canada (C.M.); Departments of Gastroenterology (J.P.) and Radiology (J. Rimola), Hospital Clínic de Barcelona, Barcelona, Spain; and Department of Medicine, Division of Gastroenterology, Western University, London, Ontario, Canada (V.J., B.G.F.).ORCID 0000-0002-8587-5441
Julian PanésFrom the Department of Inflammation and Immunity, Lerner Research Institute (F.R., R.O., N.A.), Department of Gastroenterology, Hepatology and Nutrition, Digestive Diseases (F.R., M.T.S., V.C.S.), and Program for Global Translational Inflammatory Bowel Disease Research (F.R., R.O.), Cleveland Clinic Foundation, Cleveland, Ohio; Section of Abdominal Imaging, Imaging, Digestive Diseases and Surgery and Cancer Institutes (M.E.B.) and Department of Diagnostic Radiology (J.M.R.) Cleveland Clinic Foundation, Cleveland, Ohio; Division of Gastroenterology and Hepatology (D.H.B.), Biomedical Imaging Resource (D.R.H.), and Department of Radiology (J.L.F., E.C.E., S.P.S., J.P.H., D.R.H., Y.S.L., J.G.F.), Mayo Clinic, 200 First St, Rochester, MN 55905; Department of Radiology, Shiga University of Medical Science, Shiga, Japan (A.I.); Department of Radiology, University of Texas Medical Branch, Galveston, Tex (P.M.); Centre for Medical Imaging, University College London, London, United Kingdom (S.A.T.); Department of Radiology and Nuclear Medicine, Amsterdam University Medical Centre, University of Amsterdam, Amsterdam, the Netherlands (J.S.); Alimentiv, London, Ontario, Canada (G.Z., Z.W., J. Rémillard, C.M., C.E.P., V.J., B.G.F.); Department of Epidemiology and Biostatistics, Western University, London, Ontario, Canada (G.Z., V.J., B.G.F.); Department of Quantitative Health Sciences, Mayo Clinic, Jacksonville, Fla (R.E.C.); Division of Gastroenterology and Hepatology, University of Calgary, Calgary, Alberta, Canada (C.M.); Departments of Gastroenterology (J.P.) and Radiology (J. Rimola), Hospital Clínic de Barcelona, Barcelona, Spain; and Department of Medicine, Division of Gastroenterology, Western University, London, Ontario, Canada (V.J., B.G.F.).ORCID 0000-0002-4971-6902
Jordi RimolaFrom the Department of Inflammation and Immunity, Lerner Research Institute (F.R., R.O., N.A.), Department of Gastroenterology, Hepatology and Nutrition, Digestive Diseases (F.R., M.T.S., V.C.S.), and Program for Global Translational Inflammatory Bowel Disease Research (F.R., R.O.), Cleveland Clinic Foundation, Cleveland, Ohio; Section of Abdominal Imaging, Imaging, Digestive Diseases and Surgery and Cancer Institutes (M.E.B.) and Department of Diagnostic Radiology (J.M.R.) Cleveland Clinic Foundation, Cleveland, Ohio; Division of Gastroenterology and Hepatology (D.H.B.), Biomedical Imaging Resource (D.R.H.), and Department of Radiology (J.L.F., E.C.E., S.P.S., J.P.H., D.R.H., Y.S.L., J.G.F.), Mayo Clinic, 200 First St, Rochester, MN 55905; Department of Radiology, Shiga University of Medical Science, Shiga, Japan (A.I.); Department of Radiology, University of Texas Medical Branch, Galveston, Tex (P.M.); Centre for Medical Imaging, University College London, London, United Kingdom (S.A.T.); Department of Radiology and Nuclear Medicine, Amsterdam University Medical Centre, University of Amsterdam, Amsterdam, the Netherlands (J.S.); Alimentiv, London, Ontario, Canada (G.Z., Z.W., J. Rémillard, C.M., C.E.P., V.J., B.G.F.); Department of Epidemiology and Biostatistics, Western University, London, Ontario, Canada (G.Z., V.J., B.G.F.); Department of Quantitative Health Sciences, Mayo Clinic, Jacksonville, Fla (R.E.C.); Division of Gastroenterology and Hepatology, University of Calgary, Calgary, Alberta, Canada (C.M.); Departments of Gastroenterology (J.P.) and Radiology (J. Rimola), Hospital Clínic de Barcelona, Barcelona, Spain; and Department of Medicine, Division of Gastroenterology, Western University, London, Ontario, Canada (V.J., B.G.F.).ORCID 0000-0002-1814-4198
Vipul JairathFrom the Department of Inflammation and Immunity, Lerner Research Institute (F.R., R.O., N.A.), Department of Gastroenterology, Hepatology and Nutrition, Digestive Diseases (F.R., M.T.S., V.C.S.), and Program for Global Translational Inflammatory Bowel Disease Research (F.R., R.O.), Cleveland Clinic Foundation, Cleveland, Ohio; Section of Abdominal Imaging, Imaging, Digestive Diseases and Surgery and Cancer Institutes (M.E.B.) and Department of Diagnostic Radiology (J.M.R.) Cleveland Clinic Foundation, Cleveland, Ohio; Division of Gastroenterology and Hepatology (D.H.B.), Biomedical Imaging Resource (D.R.H.), and Department of Radiology (J.L.F., E.C.E., S.P.S., J.P.H., D.R.H., Y.S.L., J.G.F.), Mayo Clinic, 200 First St, Rochester, MN 55905; Department of Radiology, Shiga University of Medical Science, Shiga, Japan (A.I.); Department of Radiology, University of Texas Medical Branch, Galveston, Tex (P.M.); Centre for Medical Imaging, University College London, London, United Kingdom (S.A.T.); Department of Radiology and Nuclear Medicine, Amsterdam University Medical Centre, University of Amsterdam, Amsterdam, the Netherlands (J.S.); Alimentiv, London, Ontario, Canada (G.Z., Z.W., J. Rémillard, C.M., C.E.P., V.J., B.G.F.); Department of Epidemiology and Biostatistics, Western University, London, Ontario, Canada (G.Z., V.J., B.G.F.); Department of Quantitative Health Sciences, Mayo Clinic, Jacksonville, Fla (R.E.C.); Division of Gastroenterology and Hepatology, University of Calgary, Calgary, Alberta, Canada (C.M.); Departments of Gastroenterology (J.P.) and Radiology (J. Rimola), Hospital Clínic de Barcelona, Barcelona, Spain; and Department of Medicine, Division of Gastroenterology, Western University, London, Ontario, Canada (V.J., B.G.F.).
Brian G FeaganFrom the Department of Inflammation and Immunity, Lerner Research Institute (F.R., R.O., N.A.), Department of Gastroenterology, Hepatology and Nutrition, Digestive Diseases (F.R., M.T.S., V.C.S.), and Program for Global Translational Inflammatory Bowel Disease Research (F.R., R.O.), Cleveland Clinic Foundation, Cleveland, Ohio; Section of Abdominal Imaging, Imaging, Digestive Diseases and Surgery and Cancer Institutes (M.E.B.) and Department of Diagnostic Radiology (J.M.R.) Cleveland Clinic Foundation, Cleveland, Ohio; Division of Gastroenterology and Hepatology (D.H.B.), Biomedical Imaging Resource (D.R.H.), and Department of Radiology (J.L.F., E.C.E., S.P.S., J.P.H., D.R.H., Y.S.L., J.G.F.), Mayo Clinic, 200 First St, Rochester, MN 55905; Department of Radiology, Shiga University of Medical Science, Shiga, Japan (A.I.); Department of Radiology, University of Texas Medical Branch, Galveston, Tex (P.M.); Centre for Medical Imaging, University College London, London, United Kingdom (S.A.T.); Department of Radiology and Nuclear Medicine, Amsterdam University Medical Centre, University of Amsterdam, Amsterdam, the Netherlands (J.S.); Alimentiv, London, Ontario, Canada (G.Z., Z.W., J. Rémillard, C.M., C.E.P., V.J., B.G.F.); Department of Epidemiology and Biostatistics, Western University, London, Ontario, Canada (G.Z., V.J., B.G.F.); Department of Quantitative Health Sciences, Mayo Clinic, Jacksonville, Fla (R.E.C.); Division of Gastroenterology and Hepatology, University of Calgary, Calgary, Alberta, Canada (C.M.); Departments of Gastroenterology (J.P.) and Radiology (J. Rimola), Hospital Clínic de Barcelona, Barcelona, Spain; and Department of Medicine, Division of Gastroenterology, Western University, London, Ontario, Canada (V.J., B.G.F.).ORCID 0000-0002-6914-3822
Joel G FletcherFrom the Department of Inflammation and Immunity, Lerner Research Institute (F.R., R.O., N.A.), Department of Gastroenterology, Hepatology and Nutrition, Digestive Diseases (F.R., M.T.S., V.C.S.), and Program for Global Translational Inflammatory Bowel Disease Research (F.R., R.O.), Cleveland Clinic Foundation, Cleveland, Ohio; Section of Abdominal Imaging, Imaging, Digestive Diseases and Surgery and Cancer Institutes (M.E.B.) and Department of Diagnostic Radiology (J.M.R.) Cleveland Clinic Foundation, Cleveland, Ohio; Division of Gastroenterology and Hepatology (D.H.B.), Biomedical Imaging Resource (D.R.H.), and Department of Radiology (J.L.F., E.C.E., S.P.S., J.P.H., D.R.H., Y.S.L., J.G.F.), Mayo Clinic, 200 First St, Rochester, MN 55905; Department of Radiology, Shiga University of Medical Science, Shiga, Japan (A.I.); Department of Radiology, University of Texas Medical Branch, Galveston, Tex (P.M.); Centre for Medical Imaging, University College London, London, United Kingdom (S.A.T.); Department of Radiology and Nuclear Medicine, Amsterdam University Medical Centre, University of Amsterdam, Amsterdam, the Netherlands (J.S.); Alimentiv, London, Ontario, Canada (G.Z., Z.W., J. Rémillard, C.M., C.E.P., V.J., B.G.F.); Department of Epidemiology and Biostatistics, Western University, London, Ontario, Canada (G.Z., V.J., B.G.F.); Department of Quantitative Health Sciences, Mayo Clinic, Jacksonville, Fla (R.E.C.); Division of Gastroenterology and Hepatology, University of Calgary, Calgary, Alberta, Canada (C.M.); Departments of Gastroenterology (J.P.) and Radiology (J. Rimola), Hospital Clínic de Barcelona, Barcelona, Spain; and Department of Medicine, Division of Gastroenterology, Western University, London, Ontario, Canada (V.J., B.G.F.).ORCID 0000-0002-8941-5434
Stenosis Therapy and Anti-Fibrosis Research (STAR) ConsortiumFrom the Department of Inflammation and Immunity, Lerner Research Institute (F.R., R.O., N.A.), Department of Gastroenterology, Hepatology and Nutrition, Digestive Diseases (F.R., M.T.S., V.C.S.), and Program for Global Translational Inflammatory Bowel Disease Research (F.R., R.O.), Cleveland Clinic Foundation, Cleveland, Ohio; Section of Abdominal Imaging, Imaging, Digestive Diseases and Surgery and Cancer Institutes (M.E.B.) and Department of Diagnostic Radiology (J.M.R.) Cleveland Clinic Foundation, Cleveland, Ohio; Division of Gastroenterology and Hepatology (D.H.B.), Biomedical Imaging Resource (D.R.H.), and Department of Radiology (J.L.F., E.C.E., S.P.S., J.P.H., D.R.H., Y.S.L., J.G.F.), Mayo Clinic, 200 First St, Rochester, MN 55905; Department of Radiology, Shiga University of Medical Science, Shiga, Japan (A.I.); Department of Radiology, University of Texas Medical Branch, Galveston, Tex (P.M.); Centre for Medical Imaging, University College London, London, United Kingdom (S.A.T.); Department of Radiology and Nuclear Medicine, Amsterdam University Medical Centre, University of Amsterdam, Amsterdam, the Netherlands (J.S.); Alimentiv, London, Ontario, Canada (G.Z., Z.W., J. Rémillard, C.M., C.E.P., V.J., B.G.F.); Department of Epidemiology and Biostatistics, Western University, London, Ontario, Canada (G.Z., V.J., B.G.F.); Department of Quantitative Health Sciences, Mayo Clinic, Jacksonville, Fla (R.E.C.); Division of Gastroenterology and Hepatology, University of Calgary, Calgary, Alberta, Canada (C.M.); Departments of Gastroenterology (J.P.) and Radiology (J. Rimola), Hospital Clínic de Barcelona, Barcelona, Spain; and Department of Medicine, Division of Gastroenterology, Western University, London, Ontario, Canada (V.J., B.G.F.).
Funding
Creeping fat and Crohn's disease associated stricturesR01DK123233 · NIDDK · CLEVELAND CLINIC LERNER COM-CWRU · PI RIEDER, FLORIAN · 2020 to 2024
$1.9MNIDDK NIH HHS R01 DK123233
Abstract
Background Clinical decision making and drug development for fibrostenosing Crohn disease is constrained by a lack of imaging definitions, scoring conventions, and validated end points. Purpose To assess the reliability of MR enterography features to describe Crohn disease strictures and determine correlation with stricture severity. Materials and Methods A retrospective study of patients with symptomatic terminal ileal Crohn disease strictures who underwent MR enterography at tertiary care centers (Cleveland Clinic: September 2013 to November 2020; Mayo Clinic: February 2008 to March 2019) was conducted by using convenience sampling. In the development phase, blinded and trained radiologists independently evaluated 26 MR enterography features from baseline and follow-up examinations performed more than 6 months apart, with no bowel resection performed between examinations. Follow-up examinations closest to 12 months after baseline were selected. Reliability was assessed using the intraclass correlation coefficient (ICC). In the validation phase, after five features were redefined, reliability was re-estimated in an independent convenience sample using baseline examinations. Multivariable linear regression analysis identified features with at least moderate interrater reliability (ICC ≥0.41) that were independently associated with stricture severity. Results Ninety-nine (mean age, 40 years ± 14 [SD]; 50 male) patients were included in the development group and 51 (mean age, 45 years ± 16 [SD]; 35 female) patients were included in the validation group. In the development group, nine features had at least moderate interrater reliability. One additional feature demonstrated moderate reliability in the validation group. Stricture length (ICC = 0.85 [95% CI: 0.75, 0.91] and 0.91 [95% CI: 0.75, 0.96] in development and validation phase, respectively) and maximal associated small bowel dilation (ICC = 0.74 [95% CI: 0.63, 0.80] and 0.73 [95% CI: 0.58, 0.87] in development and validation group, respectively) had the highest interrater reliability. Stricture length, maximal stricture wall thickness, and maximal associated small bowel dilation were independently (regression coefficients, 0.09-3.97;
Indexed as
Crohn DiseaseMagnetic Resonance ImagingAdultConstriction, PathologicFemaleHumansMaleMiddle AgedReproducibility of ResultsRetrospective Studies
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