Evidence map›Paper›PMID 39105319›Full record

ArticleThe Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association2025

Autogenous Bilateral Cleft Alveolar Bone Grafting with rhBMP-2 and Cellular Bone Matrix.

Lucas M Harrison, Rami R Hallac, James Seaward, Alex A Kane, Yong-Jong Park

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Lucas M HarrisonDepartment of Plastic Surgery, University of Texas Southwestern Medical Center, Dallas, TX, USA.ORCID 0000-0002-3168-1879
Rami R HallacDepartment of Plastic Surgery, University of Texas Southwestern Medical Center, Dallas, TX, USA.ORCID 0000-0001-9025-399X
James SeawardDepartment of Plastic Surgery, University of Texas Southwestern Medical Center, Dallas, TX, USA.
Alex A KaneDepartment of Plastic Surgery, University of Texas Southwestern Medical Center, Dallas, TX, USA.
Yong-Jong ParkDepartment of Orthodontics, Children's Medical Center, Dallas, TX, USA.ORCID 0000-0002-1933-9835

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Alveolar bone grafting (ABG) in bilateral cleft lip and palate (BCLP) patients provides a reconstructive challenge. We present a novel technique of combining autologous iliac crest bone graft (ICBG) with recombinant human bone morphogenic protein 2 (rhBMP-2) and cellular bone matrix (CBM) for ABG in BCLP patients. Complete bone fill occurred in 90% of patients, with 100% having bilateral canine eruption. No patients required repeat ABG, and no significant complications were reported. The alveolar cleft gap volume significantly decreased with an improvement of 75.87%. ABG with autologous ICBG with rhBMP-2 and CBM is an effective technique for patients with BCLP.

Indexed as

Alveolar Bone GraftingBone MatrixBone Morphogenetic Protein 2Bone TransplantationCleft LipCleft PalateTransforming Growth Factor betaChildFemaleHumansIliumMaleRecombinant ProteinsTransplantation, AutologousTreatment OutcomeBone Morphogenetic Protein 2recombinant human bone morphogenetic protein-2Recombinant ProteinsTransforming Growth Factor betaallographsbone graftingcleft lip and palatesurgical technique

Identifiers

PMID39105319
PMCPMC12405639

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.