Evidence map›Paper›PMID 39105131›Full record

ArticlePulmonary circulation2024

Air travel in patients suffering from pulmonary hypertension-A prospective, multicentre study.

Athiththan Yogeswaran, Jan Grimminger, Khodr Tello, Lukas Becker, Werner Seeger, Friedrich Grimminger, Natascha Sommer, Hossein A Ghofrani, Tobias J Lange, Stefan Stadler and 17 more

Registry-linked trialAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Pulmonary circulation, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03051763 (PEGASUS - The Effects of Commercial Air Travel on Patients Suffering From Pulmonary Hypertension), which is not on this map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03051763 unknown statusnot on this map

PEGASUS - The Effects of Commercial Air Travel on Patients Suffering From Pulmonary Hypertension: A Prospective, Multicentric Analysis

TypeobservationalSponsorUniversity of GiessenRan2017 to 2022Enrolled1,000ConditionsPulmonary Hypertension, Pulmonary Arterial Hypertension
3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

27 authors.

Athiththan YogeswaranDepartment of Internal Medicine, Justus-Liebig-University Giessen Universities of Giessen and Marburg Lung Center (UGMLC), Member of the German Center for Lung Research (DZL) Giessen Germany.ORCID 0000-0001-9505-8608
Jan GrimmingerDepartment of Internal Medicine, Justus-Liebig-University Giessen Universities of Giessen and Marburg Lung Center (UGMLC), Member of the German Center for Lung Research (DZL) Giessen Germany.
Khodr TelloDepartment of Internal Medicine, Justus-Liebig-University Giessen Universities of Giessen and Marburg Lung Center (UGMLC), Member of the German Center for Lung Research (DZL) Giessen Germany.
Lukas BeckerDepartment of Internal Medicine, Justus-Liebig-University Giessen Universities of Giessen and Marburg Lung Center (UGMLC), Member of the German Center for Lung Research (DZL) Giessen Germany.
Werner SeegerDepartment of Internal Medicine, Universities of Giessen and Marburg Lung Center (UGMLC) Institute for Lung Health (ILH), Cardio-Pulmonary Institute (CPI), Member of the German Center for Lung Research (DZL) Giessen Germany.ORCID 0000-0003-1946-0894
Friedrich GrimmingerDepartment of Internal Medicine, Universities of Giessen and Marburg Lung Center (UGMLC) Institute for Lung Health (ILH), Cardio-Pulmonary Institute (CPI), Member of the German Center for Lung Research (DZL) Giessen Germany.
Natascha SommerDepartment of Internal Medicine, Justus-Liebig-University Giessen Universities of Giessen and Marburg Lung Center (UGMLC), Member of the German Center for Lung Research (DZL) Giessen Germany.
Hossein A GhofraniDepartment of Internal Medicine, Justus-Liebig-University Giessen Universities of Giessen and Marburg Lung Center (UGMLC), Member of the German Center for Lung Research (DZL) Giessen Germany.ORCID https://orcid.org/0000-0002-2029-4419
Tobias J LangeDepartment of Internal Medicine II, Pulmonology and Intensive Care Kreisklinik Bad Reichenhall Bad Reichenhall Germany.
Stefan StadlerDepartment of Internal Medicine II University Medical Center Regensburg Regensburg Germany.
Karen OlssonDepartment of Respiratory Medicine and Infectious Diseases Hannover Medical School Hannover Germany.
Jan C KampDepartment of Respiratory Medicine and Infectious Diseases Hannover Medical School Hannover Germany.ORCID https://orcid.org/0000-0002-5002-409X
Stephan RosenkranzKlinik III für Innere Medizin Herzzentrum der Universität zu Köln Cologne Germany.
Felix GerhardtKlinik III für Innere Medizin Herzzentrum der Universität zu Köln Cologne Germany.
Katrin MilgerDepartment of Medicine V, LMU University Hospital, LMU Munich, Comprehensive Pneumology Center Member of the German Center for Lung Research (DZL) Giessen Germany.
Michaela BarnikelDepartment of Medicine V, LMU University Hospital, LMU Munich, Comprehensive Pneumology Center Member of the German Center for Lung Research (DZL) Giessen Germany.
Silvia UlrichDepartment of Respiratory Medicine, Pulmonary Hypertension Unit University Hospital Zurich Zurich Switzerland.
Stéphanie SaxerDepartment of Respiratory Medicine, Pulmonary Hypertension Unit University Hospital Zurich Zurich Switzerland.
Ekkehard GrünigThoraxklinik-Heidelberg gGmbH German Center for Lung Research (DZL) Heidelberg Germany.
Satenik HarutynovaThoraxklinik-Heidelberg gGmbH German Center for Lung Research (DZL) Heidelberg Germany.
Christian OpitzDepartment of Cardiology DRK Kliniken Berlin Westend Berlin Germany.
Hans KloseDepartment of Respiratory Medicine Eppendorf University Hospital Hamburg Germany.
Heinrike WilkensKlinik fur Innere Medizin V, Pneumologie Universitätsklinikum des Saarlandes Homburg Germany.
Michael HalankInternal Medicine I-Department of Pneumology University Hospital Carl Gustav Carus of TU Dresden Germany.
Melanie HeberlingInternal Medicine I-Department of Pneumology University Hospital Carl Gustav Carus of TU Dresden Germany.ORCID 0009-0003-4731-5800
Henning GallDepartment of Internal Medicine, Justus-Liebig-University Giessen Universities of Giessen and Marburg Lung Center (UGMLC), Member of the German Center for Lung Research (DZL) Giessen Germany.ORCID 0000-0001-7016-7373
Manuel J RichterDepartment of Internal Medicine, Justus-Liebig-University Giessen Universities of Giessen and Marburg Lung Center (UGMLC), Member of the German Center for Lung Research (DZL) Giessen Germany.ORCID 0000-0003-0964-1931

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The PEGASUS study is the first multicentric and prospective assessment of the safety of air travel flying in pulmonary hypertension (PH) (NCT03051763). Data of air travel from 60 patients with PH was available. No severe adverse events occurred. Nine patients self-reported mild adverse events during flight (13%), while after landing, 12 patients reported events (20%). Solely one patient (2%) had an adverse event leading to medical consultation. In patients with PH and World Health Organization functional classes II and III, air travel was safe.

Indexed as

flightpatient behaviorpulmonary arterial hypertension

Identifiers

PMID39105131
PMCPMC11298895

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.