Evidence map›Paper›PMID 39105120›Full record

ArticleJACC. Advances2024

30-Year Trends in the Incidence, Characteristics, and Outcome of Cardiac Sarcoidosis in a Nationwide Cohort.

Pauli Pöyhönen, Jukka Lehtonen, Diana Velikanova, Piia Simonen, Valtteri Uusitalo, Henriikka Mälkönen, Hanna-Kaisa Nordenswan, Tapani Vihinen, Kari Kaikkonen, Petri Haataja and 6 more

Abstract read
In one paragraph

Article in JACC. Advances, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Catheter ablation of atrial fibrillation in patients with cardiac amyloidosis and sarcoidosis: procedural findings and outcomes.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2025
    Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Pauli PöyhönenHeart and Lung Center, Helsinki University Hospital and University of Helsinki, Helsinki, Finland.
Jukka LehtonenHeart and Lung Center, Helsinki University Hospital and University of Helsinki, Helsinki, Finland.
Diana VelikanovaHeart and Lung Center, Helsinki University Hospital and University of Helsinki, Helsinki, Finland.
Piia SimonenHeart and Lung Center, Helsinki University Hospital and University of Helsinki, Helsinki, Finland.
Valtteri UusitaloRadiology, Helsinki University Hospital and University of Helsinki, Helsinki, Finland.
Henriikka MälkönenHeart and Lung Center, Helsinki University Hospital and University of Helsinki, Helsinki, Finland.
Hanna-Kaisa NordenswanHeart and Lung Center, Helsinki University Hospital and University of Helsinki, Helsinki, Finland.
Tapani VihinenHeart Center, Turku University Hospital, Turku, Finland.
Kari KaikkonenMedical Research Center Oulu, University and University Hospital of Oulu, Oulu, Finland.
Petri HaatajaHeart Hospital, Tampere University Hospital, Tampere, Finland.
Tuomas KerolaDepartment of Internal Medicine, Päijät-Häme Central Hospital, Lahti, Finland.
Tuomas T RissanenHeart Center, North Karelia Central Hospital, Joensuu, Finland.
Ville VepsäläinenHeart Centre, Kuopio University Hospital, Kuopio, Finland.
Aleksi AlataloSouth Ostrobothnia Central Hospital, Seinäjoki, Finland.
Päivi Pietilä-EffatiVaasa Central Hospital, Vaasa, Finland.
Markku KupariHeart and Lung Center, Helsinki University Hospital and University of Helsinki, Helsinki, Finland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Cardiac sarcoidosis (CS) is a rare but potentially fatal inflammatory cardiomyopathy. Objectives: The authors studied temporal changes in the incidence, characteristics, and outcome of CS. Methods: A retrospective analysis was made of a 30-year nationwide cohort of CS. Results: The cohort comprised 511 patients with a median age of 52 years and female preponderance (69%). Altogether 77, 166, and 268 cases of CS were diagnosed in years 1988 to 2009, 2010 to 2014, and 2015 to 2019, respectively; the 5-year count of 2015 to 2019 was 134-fold the count of 1990 to 1994 (268/2) and 18-fold the count of 2000 to 2004 (268/15). Prior to 2010, compared with the later periods, CS presented more often with ventricular tachycardia/fibrillation (prevalence 36% vs 19% in 2010-2014 and 11% in 2015-2019, Conclusions: Diagnoses of incident CS have increased exponentially in Finland. Concurrently, the phenotype has turned milder and prognosis better, suggesting detection of CS at an earlier stage of its course.

Indexed as

cardiac sarcoidosisdiagnostic imagingincidencephenotypeprognosis

Identifiers

PMID39105120
PMCPMC11298841

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.