ArticleERJ open research2024
Symptom burden and its associations with clinical characteristics in patients with COPD: a clustering approach.
Article in ERJ open research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed.
- Translation, cross-cultural adaptation and psychometric evaluation of the Portuguese version of the self-care in chronic obstructive pulmonary disease inventory.International journal of nursing studies advances · 2026Article
- Real-Time Symptom Ratings Using Ecological Momentary Assessment Versus Traditional Questionnaires in Patients With Chronic Obstructive Pulmonary Disease: Observational Study.JMIR medical informatics · 2026Observational
- A longitudinal study on the correlation between symptom clusters and disease-specific health status in older adults with chronic obstructive pulmonary disease during pulmonary rehabilitation.Frontiers in public health · 2026Article
- Chronic Obstructive Pulmonary Disease in Never-Smokers-A Distinct Entity Within the COPD Spectrum.Life (Basel, Switzerland) · 2025Review
- A survey and analysis of inhalation medication adherence among 977 COPD patients in a region of northern China.European journal of medical research · 2025Article
- Identifying the Core Symptoms in Chinese Patients of Chronic Obstructive Pulmonary Disease: A Contemporaneous Symptom Network Analysis.International journal of chronic obstructive pulmonary disease · 2025Article
- How People with COPD Perceive and Communicate Exacerbations: A Multicountry Survey Study.International journal of chronic obstructive pulmonary disease · 2025Article
- Peeping at COPD through the keyhole: time to broaden the view to the complexity of the disease by the heterogeneity of symptoms.ERJ open research · 2024Article
- Underutilization of palliative care in advanced COPD and heart failure: associations, disparities, and the role of specialists.Therapeutic advances in respiratory diseaseObservational
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Symptom burden in patients with COPD is often under-recognised. In this cross-sectional analysis, we aimed to study the severity of a variety of (non-)respiratory symptoms in patients with and without COPD and to explore the associations between clusters based on symptom severity and other clinical characteristics. Methods: Characteristics were assessed in 538 patients with COPD from primary, secondary and tertiary care and 116 non-COPD participants. The severity of 20 symptoms was measured using a visual analogue scale (VAS), ranging from 0 mm (no symptom) to 100 mm (maximum severity). K-means cluster analysis was applied to symptom severity in the patient sample only. Results: People with COPD were comparable with non-COPD participants in terms of gender (58% Conclusions: People with COPD report a high burden of respiratory as well as non-respiratory symptoms. Cluster analysis demonstrated a co-occurrence of different levels of symptom severity, highlighting the heterogeneity of symptoms experience. Identifying clusters of patients with shared symptom experiences will help us to understand the impact of the disease and define integrated, multidimensional treatment strategies.
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Registered trials
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