Evidence map›Paper›PMID 39104902›Full record

ArticleMaterials today. Bio2024

Enhanced vascularization and osseointegration under osteoporotic conditions through functional peptide coating on implant surfaces.

Jiming Liu, Bingyang Zhao, Xinkun Shen, Dandan Lu, Wei He, Xingjie Zan, Lianxin Li, Yihuai Pan

Abstract read
In one paragraph

Article in Materials today. Bio, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
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  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Jiming LiuSchool & Hospital of Stomatology, Wenzhou Medical University, Wenzhou, 325000, China.
Bingyang ZhaoThe Department of Stomatology, The First Affiliated Hospital of Ningbo University, Ningbo, 315010, China.
Xinkun ShenDepartment of Orthopaedics, The Third Affiliated Hospital of Wenzhou Medical University (Ruian People's Hospital), Wenzhou, 325016, China.
Dandan LuSchool & Hospital of Stomatology, Wenzhou Medical University, Wenzhou, 325000, China.
Wei HeSchool & Hospital of Stomatology, Wenzhou Medical University, Wenzhou, 325000, China.
Xingjie ZanWenzhou Key Laboratory of Perioperative Medicine, Wenzhou Institute, University of Chinese Academy of Sciences, Wenzhou, 325000, China.
Lianxin LiDepartment of Orthopaedics Surgery, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan City, Shandong Province, 250021, China.
Yihuai PanSchool & Hospital of Stomatology, Wenzhou Medical University, Wenzhou, 325000, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Patients with osteoporosis face challenges such as decreased bone density, a sparse trabecular structure, weakened osteogenic ability, and impaired angiogenesis, leading to poor osseointegration and implant failure. Surface modification of implants with biologically active molecules possessing various functions is an effective strategy to improve osseointegration. In this study, we constructed a simple multifunctional coating interface that significantly improves osseointegration. In brief, a multifunctional coating interface was constructed by coupling the Rgd adhesive peptide, Ogp osteogenic peptide, and Ang angiogenic peptide to Lys

Indexed as

Bone regenerationMultifunctional coatingsOsseointegrationOsteoporotic bone defectsVascularization

Identifiers

PMID39104902
PMCPMC11298615

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.