Evidence map›Paper›PMID 39104759›Full record

ArticleFrontiers in nutrition2024

The interaction between polyphenol intake and genes (MC4R, Cav-1, and Cry1) related to body homeostasis and cardiometabolic risk factors in overweight and obese women: a cross-sectional study.

Zahra Roumi, Atieh Mirzababaei, Faezeh Abaj, Soheila Davaneghi, Yasaman Aali, Khadijeh Mirzaei

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Article in Frontiers in nutrition, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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1citing papers in PubMed
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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Zahra RoumiDepartment of Nutrition, Science and Research Branch, Islamic Azad University, Tehran, Iran.
Atieh MirzababaeiDepartment of Nutrition, Science and Research Branch, Islamic Azad University, Tehran, Iran.
Faezeh AbajDepartment of Nutrition, Dietetics and Food, School of Clinical Sciences at Monash Health, Monash University, Clayton, VIC, Australia.
Soheila DavaneghiMSC, School of Nutrition and Food Sciences, Tabriz University of Medical Sciences, Tabriz, Iran.
Yasaman AaliDepartment of Nutrition, Science and Research Branch, Islamic Azad University, Tehran, Iran.
Khadijeh MirzaeiDepartment of Nutrition, Science and Research Branch, Islamic Azad University, Tehran, Iran.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Cardiovascular disease (CVD), which is an important global health challenge, is expanding. One of the main factors in the occurrence of CVD is a high genetic risk. The interaction between genetic risk in CVD and nutrition is debatable. Polyphenols are one of the important dietary components that may have a protective role in people who have a high genetic risk score (GRS) for cardiometabolic risk factors. This study, conducted in overweight and obese women, examines the interaction between polyphenol intake and specific genes (MC4r, Cav-1, and Cry1) related to maintaining body balance and their interaction with cardiometabolic risk factors. Methods: This cross-sectional study included 391 women who were overweight or obese, aged 18 to 48 years, with a body mass index (BMI) between 25 and 40 kg/m Results: The mean ± standard deviation (SD) age and BMI of women were 36.67 (9.1) years and 30.98 (3.9) kg/m Conclusion: According to our findings, those with a high GRS may have a protective effect on cardiometabolic risk factors by consuming high amounts of polyphenols. Further studies will be necessary in the future to validate this association.

Indexed as

cardiometabolic risk factorsgenetic risk scorehomeostasisobesitypolyphenols

Identifiers

PMID39104759
PMCPMC11299215

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