Evidence map›Paper›PMID 39104652›Full record

ArticleSkin health and disease2024

Re-engagement, quality of life, and burden of treatment in adults on dupilumab for severe atopic dermatitis-A mixed methods study.

Emma Porter, Cathal O'Connor, Michelle Murphy

Abstract read
In one paragraph

Article in Skin health and disease, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Emma PorterDermatology South Infirmary Victoria University Hospital Cork Ireland.ORCID https://orcid.org/0000-0002-5532-5799
Cathal O'ConnorDermatology South Infirmary Victoria University Hospital Cork Ireland.ORCID https://orcid.org/0000-0001-7084-5293
Michelle MurphyDermatology South Infirmary Victoria University Hospital Cork Ireland.ORCID https://orcid.org/0000-0003-2431-076X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Targeted biologic therapies have revolutionised the treatment of severe atopic dermatitis (AD). Objectives: To assess effects of dupilumab on patient re-engagement, quality of life (QOL), and burden of treatment (BOT) in severe AD. Methods: Adults on dupilumab for AD completed questionnaires on QOL, BOT, and provided qualitative reflections, with a subset interviewed to explore experience of leaving and re-engaging with dermatology. Prior treatments, adverse events, and clinical severity scoring were evaluated. Statements and interviews were qualitatively reviewed. Results: Of 41 patients; median age was 34 years, 68% were male; and 93% ( Conclusions: The emergence of novel effective treatments for AD has significant implications for dermatology workforce and financial planning.

Identifiers

PMID39104652
PMCPMC11297430

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.